2234276-60-7

2234276-60-7 structure

Name: AP-C6
Chemical Name: AP-C6
CAS Number: 2234276-60-7
Molecular Formula: C₁₅H₁₅N₅O
Molecular Weight: 281.31
Catalog: Research Areas Others
Create Date: 2024-01-09 11:29:03
Modify Date: 2024-01-09 11:29:03
AP-C6 is a potent inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 6.5. AP-C6 concentration-dependently inhibits human cGKII activity in vitro. AP-C6 potentiate cAMP signaling by PDE inhibition[1].

Name	AP-C6

Description	AP-C6 is a potent inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 6.5. AP-C6 concentration-dependently inhibits human cGKII activity in vitro. AP-C6 potentiate cAMP signaling by PDE inhibition[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	pIC50: 6.5 (cGKII)[1]
References	[1]. Marcel J C Bijvelds, et al. Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. J Biol Chem. 2018 May 25;293(21):8173-8181.

Molecular Formula	C₁₅H₁₅N₅O
Molecular Weight	281.31