Butyl oleate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Ammonium sulphate-d8 is the deuterium labeled Ammonium sulphate,≥99.0%,AR[1]. Ammonium sulphate,≥99.0%,AR is an inorganic sulfate salt used for molecular biology[2].
9-Methoxyaristolactam I is a natural product that can be isolated from the roots of Asarum sieboldii Miq. var. Seoulense Nakai[1].
Agarose,for biochemistry is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
MeOSuc-Ala-Ala-Pro-Val-4-MNA is a elastase fluorogenic substrate that can be detected at 425 nm (with excitation at 340 nm)[1].
Phenylbenzothiazole-PEG4-OH (compound 1) can treat spinal cord injury and promote spine formation[1].
N-[(Benzyloxy)carbonyl]-L-alanine is an alanine derivative[1].
1-Hexadecylpyridin-1-ium bromide-d5 is the deuterium labeled 1-Hexadecylpyridin-1-ium bromide[1].
EE epitope is a biological active peptide. (This peptide is a 314 to 319 amino acids fragment of the middle T antigen of mouse polymavirus. Glu-Glu epitope peptide is widely used as an epitope tag.Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)
5-O-(3'-O-Glucosylcaffeoyl)quinic acid (compound 19) is a phenolic compound found in the leaves of Ilex glabra L. Gray (Aquifoliaceae)[1].
Omadacycline-d9 is a deuterated aminomethylcycline omadacycline (HY-14865). Omadacycline is an orally active antibacterial agent and tetracycline antibiotic. Omadacycline binds to the 30S ribosomal subunit to inhibit bacterial protein synthesis. Omadacycline tosylate is indicated for the study of acute bacterial skin and skin structure infections, infectious pneumonia and urinary tract infections.
Benfluralin is a kind of herbicide and an agrochemical which can be used as a pre-emergence herbicide used for the control of grass and other weeds in a range of food and non-food crops.
8-Hydroxy-3,5,6,7,3',4'-hexamethoxyflavone is a polymethoxyflavone (PMF) isolated from pericarpium citri reticulatae.
4-Hydroxymethylpyrazole is the primary metabolite of Fomepizole (HY-B0876). Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase[1].
Febuxostat dicarboxylic acid impurity is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM[1].
tert-Butyl (1-hydroxypropan-2-yl)carbamate-d6 is the deuterium labeled tert-Butyl (1-hydroxypropan-2-yl)carbamate[1].
2-Amino-3-(naphthalen-1-yl)propanoic acid is an alanine derivative[1].
Vanillyl alcohol (Vanillic alcohol), derived from vanillin, is a phenolic alcohol and is used as a flavoring agent in foods and beverages[1].
KALA is an amphiphilic peptide that forms an α-helical structure at physiological pH. KALA modifies a plasmid DNA-encapsulating liposomal membrane and is used as a fusogenic peptide in order to achieve effective liver targeting and transfection of DNA via galactose receptors[1].
Kaempferol-3-O-(6'''-trans-p-coumaroyl-2''-glucosyl)rhamnoside is a natural antioxidant from herbal medicines[1].
((3-Chlorophenyl)sulfonyl)proline is a proline derivative containing amino and carboxyl groups.
8-Allyloxyguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Keracyanin chloride (Cyanidin 3-rutinoside chloride), an anthocyanin, has antioxidant activity. Keracyanin chloride inhibits malonaldehyde formation in oxidized calf thymus DNA[1][2].
Gynosaponin I (compound 1) is a natural product that can be found in Gynostemma pentaphyllum[1].
2,3-O-Isopropylidene-D-erythronolactone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
N-(2-Cyanoethyl)glycine is a Glycine (HY-Y0966) derivative[1].
SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.IC50 value: 0.1 nM(Ki) [1]Target: 15-PGDHin vitro: SW033291 inhibition of 15-PGDH was noncompetitive versus PGE2 over concentrations up to 40 μM PGE2. SW033291 also demonstrated selective high-affinity interaction with 15-PGDH in thermal denaturation assays. Treatment of A549 cells with SW033291 increased PGE2 levels by 3.5-fold at 500 nM, with 50% of maximal stimulation (EC50) at ~75 nM [1].in vivo: mice injected with SW033291 closely phenocopied 15-PGDH knockout mice, with 10 mg per kg of weight (mg/kg) SW033291 inducing a twofold increase in PGE2 levels in bone marrow, colon, lung, and liver. Mice injected with SW033291 at 20 mg/kg daily for 7 days showed equivalent daily weights and activity as mice injected with vehicle-control and showed no adverse changes in blood counts or serum chemistry [1].
Nurr1 agonist 8 (compound 111) is a Nurr1 agonist with an EC50 value of 0.09 μM[1].
Hemoglobin is a iron-containing protein in red blood cells with oxygen binding properties. Hemoglobin consits of heme, which binds to oxygen. Hemoglobin also transports other gases, such as carbon dioxide, nitric oxide, hydrogen sulfide and sulfide. Hemoglobin absorbs unneeded oxygen in tissues, as an antioxidant[1].
Caulophylline B is a fluorenone alkaloid isolated from the roots of Caulophyllum robustum Maxim, affords a low scavenging effect against DPPH radical[1].