KALA

Modify Date: 2025-08-25 17:28:13

KALA Structure
KALA structure
Common Name KALA
CAS Number 187987-64-0 Molecular Weight 3131.822
Density 1.2±0.1 g/cm3 Boiling Point 2669.2±65.0 °C at 760 mmHg
Molecular Formula C144H248N40O35S Melting Point N/A
MSDS N/A Flash Point 1568.1±34.3 °C

 Use of KALA


KALA is an amphiphilic peptide that forms an α-helical structure at physiological pH. KALA modifies a plasmid DNA-encapsulating liposomal membrane and is used as a fusogenic peptide in order to achieve effective liver targeting and transfection of DNA via galactose receptors[1].

 Names

Name KALA Amphipathic Peptide
Synonym More Synonyms

 KALA Biological Activity

Description KALA is an amphiphilic peptide that forms an α-helical structure at physiological pH. KALA modifies a plasmid DNA-encapsulating liposomal membrane and is used as a fusogenic peptide in order to achieve effective liver targeting and transfection of DNA via galactose receptors[1].
Related Catalog
In Vitro When a plasmid DNA-encapsulating liposomal membrane is modified with the KALA peptide, transgene expression and immune activation are facilitated in bone marrow-derived dendritic cells (BMDCs)[1].
References

[1]. Naoya Miura, et al. Identification and Evaluation of the Minimum Unit of a KALA Peptide Required for Gene Delivery and Immune Activation. J Pharm Sci. 2017 Oct;106(10):3113-3119.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 2669.2±65.0 °C at 760 mmHg
Molecular Formula C144H248N40O35S
Molecular Weight 3131.822
Flash Point 1568.1±34.3 °C
Exact Mass 3129.857666
LogP -1.26
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.555

 Synonyms

L-Alanine, L-tryptophyl-L-α-glutamyl-L-alanyl-L-lysyl-L-leucyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-histidyl-L-leucyl-L-alanyl-L-lysyl-L-alanyl- L-leucyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-lysyl-L-alanyl-L-cysteinyl-L-α-glutamyl-
L-Tryptophyl-L-α-glutamyl-L-alanyl-L-lysyl-L-leucyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-alanyl-L-lysyl-L-histidyl-L-leucyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L- alanyl-L-lysyl-L-alanyl-L-leucyl-L-lysyl-L-alanyl-L-cysteinyl-L-α-glutamyl-L-alanine
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.