126138-81-6

126138-81-6 structure

Name: 8-Allyloxyguanosine
Chemical Name: 8-(Allyloxy)guanosine
CAS Number: 126138-81-6
Molecular Formula: C₁₃H₁₇N₅O₆
Molecular Weight: 339.30
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2016-05-19 23:39:44
Modify Date: 2025-08-24 23:42:06
8-Allyloxyguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	8-(Allyloxy)guanosine
Synonyms	8-(2-Propenyl)oxyguanosine 8-(allyloxy)-2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one

Description	8-Allyloxyguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

4016-63-1

107-18-6

~63%

126138-81-6

Literature: Nucleosides and Nucleotides, , vol. 13, # 1-3 p. 551 - 562

4016-63-1

~19%

557-40-4

126138-81-6

Literature: US5011828 A1, ;

20907-32-8

4016-63-1

~68%

126138-81-6

Literature: Journal of Medicinal Chemistry, , vol. 37, # 21 p. 3561 - 3578