Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Dorlimomab aritox

Dorlimomab aritox (4197X-RA; MDX-RA (ricin A chain) immunotoxin) is a mouse-derived monoclonal antibody conjugated to ricin A[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Arctiol

Arctiol is a natural product that can be found in Podocarpus fleuryi[1].

  • CAS Number: 36061-11-7
  • MF: C15H26O2
  • MW: 238.36600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Quinolactactin A

(S)-Quinolactacine A is a TNF production inhibitor[1].

  • CAS Number: 319917-25-4
  • MF: C16H18N2O2
  • MW: 270.326
  • Catalog: Inflammation/Immunology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 458.0±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 230.8±28.7 °C

Dynorphin (2-17) (porcine)

Dynorphin (2-17) (porcine) is a peptide derived from Prodynorphin, can improve somatic signs of Morphine-dependent withdrawal[1].

  • CAS Number: 83608-80-4
  • MF: C90H146N30O21
  • MW: 1984.31000
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SRT1720 HCl

SRT 1720 Hydrochloride is a selective activator of SIRT1 with an EC1.5 of 0.16 μM, and shows less potent activities on SIRT2 and SIRT3 with EC1.5s of 37 μM and 300 μM, respectively.

  • CAS Number: 1001645-58-4
  • MF: C25H23N7OS.xHCl
  • MW: 506.022
  • Catalog: Autophagy
  • Density: 1.58
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Nicomol

Nicomol is an orally active hypolipidemic agent that can increase the high density lipoprotein cholesterol (HDL-C) level. Nicomol inhibits the rapid rise of plasma free fatty acids[1][2].

  • CAS Number: 27959-26-8
  • MF: C34H32N4O9
  • MW: 640.64
  • Catalog: Cardiovascular Disease
  • Density: 1.316g/cm3
  • Boiling Point: 763.3ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 415.4ºC

Siraitic acid B

Siraitic Acid B is a cucurbitane triterpenoid isolated from the root of S. grosvenori [1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-(3-hydroxyphenyl)-Arachidonoyl amide

N-(3-Hydroxyphenyl)-arachidonoyl amide (Compound 23) is an anandamide transport inhibitor with an IC50 of 21.3 μM[1].

  • CAS Number: 183718-75-4
  • MF: C26H37NO2
  • MW: 395.58
  • Catalog: Neurological Disease
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 579.4±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 304.2±30.1 °C

9,10-Dichlorostearic acid

9,10-Dichlorostearic acid is a chlorinated stearic acid with antimutagenic properties. 9,10-Dichlorostearic acid can cause membrane damage by inducing leakage of adenosine triphosphate (ATP) from mammalian tumour cells in vitro[1].

  • CAS Number: 5829-48-1
  • MF: C18H34Cl2O2
  • MW: 353.367
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 457.2±25.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 230.3±23.2 °C

Tetrahydropalmatrubine

Tetrahydropalmatrubine is an alkaloid that can be isolated from the herb of Corydalis saxicola[1].

  • CAS Number: 7762-76-7
  • MF: C20H23NO4
  • MW: 341.40
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-8-methyl-3,9-dihydro-6H-purin-6-one

2′-O-Methyl-8-methyl guanosine is a Z-form RNA stabilizer. 2′-O-Methyl-8-methyl guanosine can markedly stabilize the Z-RNA at low salt conditions[1].

  • CAS Number: 2306782-64-7
  • MF: C12H17N5O5
  • MW: 311.29
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Amino[3-(trifluoromethyl)phenyl]acetic acid

2-Amino-2-(3-(trifluoromethyl)phenyl)acetic acid is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 242475-26-9
  • MF: C9H8F3NO2
  • MW: 219.161
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 274.0±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 119.5±27.3 °C

Implitapide Racemate

Implitapide Racemate is the racemate of Implitapide. Implitapide is a microsomal triglyceride transfer protein (MTP) inhibitor.

  • CAS Number: 177277-99-5
  • MF: C35H37N3O2
  • MW: 531.69
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4,4'-Sulfonyldiphenol-d8

4,4'-Sulfonyldiphenol-d8 is the deuterium labeled 4,4'-Sulfonyldiphenol[1].

  • CAS Number: 2483831-28-1
  • MF: C12H2D8O4S
  • MW: 258.32
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

6-Acetonyldihydrosanguinarine

6-Acetonyldihydrosanguinarine is a compound isolated from the aerial parts of Chelidonium majus L..[1]

  • CAS Number: 37687-34-6
  • MF: C23H19NO5
  • MW: 389.401
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 597.3±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 315.0±30.1 °C

Endotoxin Substrate acetate salt

Endotoxin Substrate (Boc-LGR-pNA) is a chromogenic substrate can be used in quantitative assays of endotoxin[1].

  • CAS Number: 68223-96-1
  • MF: C25H40N8O7
  • MW: 564.635
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N,N'-Bis(2,6-dimethylphenyl)-1,4-piperazinediacetamide-d8

N,N'-Bis(2,6-dimethylphenyl)-1,4-piperazinediacetamide-d8 is the deuterium labeled N,N'-Bis(2,6-dimethylphenyl)-1,4-piperazinediacetamide[1].

  • CAS Number: 2751283-52-8
  • MF: C24H24D8N4O2
  • MW: 416.59
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Methyl-5-acetonyl-7-hydroxychromone

Cassiachromone can be isoalted from Cassia siamea[1].

  • CAS Number: 28955-30-8
  • MF: C13H12O4
  • MW: 232.232
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 444.7±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 174.8±22.2 °C

Furosine dihydrochloride

Furosine dihydrochloride, an amino acid derivative, is an important chemical marker of early-stage Maillard reactions. Furosine dihydrochloride is closely related to a variety of diseases such as diabetes[1][2].

  • CAS Number: 157974-36-2
  • MF: C12H20Cl2N2O4
  • MW: 327.204
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Lucidenic acid K

Lucidenic acid K is a ganoderma acid isolated from strain G. lucidum fruiting body (YK-02)[1].

  • CAS Number: 110241-31-1
  • MF: C27H36O7
  • MW: 472.57
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-(3-NITRO-2-PYRIDINESULFENYL)-L-GLUTAMIC ACID GAMMA-T-BUTYL ESTER

N-(3-Nitro-2-pyridinesulfenyl)-L-glutamic acid γ-t-butyl ester is a glutamic acid derivative[1].

  • CAS Number: 108312-25-0
  • MF: C14H19N3O6S
  • MW: 357.38200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

LysoTracker Red

LysoTracker Red (LysoTracker Red DND-99) is a paraformaldehyde fixable probe that concentrates into acidic compartments of cells and tissues. LysoTracker Red is an indicator of cell death in a manner similar to other standard assays (Annexin, terminal dUTP nick end labeling, Nile blue sulfate, neutral red, and acridine orange)[1]. LysoTracker Red is a marker for late endosomes and lysosomes[2].

  • CAS Number: 231946-72-8
  • MF: C20H24BF2N5O
  • MW: 399.25
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(-)-Haplomyrfolin

(-)-Haplomyrfolin is a natural lignan with anticancer effects[1].

  • CAS Number: 85404-48-4
  • MF: C20H20O6
  • MW: 356.36900
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ARD-69

ARD-69 (compound 34) is a potent PROTAC androgen receptor degrader. ARD-69 induces degradation of androgen receptor (AR) protein in AR-positive prostate cancer cell lines. ARD-69 suppresses AR-regulated gene expression[1].

  • CAS Number: 2316837-10-0
  • MF: C62H74ClFN8O7S
  • MW: 1129.82
  • Catalog: PROTAC
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-β-homo-Asp(OtBu)-OH

Fmoc-β-HoAsp(OtBu)-OH is a glutamic acid derivative[1].

  • CAS Number: 209252-17-5
  • MF: C24H27NO6
  • MW: 425.47400
  • Catalog: Others
  • Density: 1.232g/cm3
  • Boiling Point: 637ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 339.1ºC

Boc-D-phe(3-F)-OH

N-BOC-3-Fluoro-D-phenylalanine is a phenylalanine derivative[1].

  • CAS Number: 114873-11-9
  • MF: C14H18FNO4
  • MW: 283.295
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 425.0±40.0 °C at 760 mmHg
  • Melting Point: 70ºC
  • Flash Point: 210.8±27.3 °C

(Leu15)-Gastrin I (human)

[Leu15]-Gastrin I (human) is a peptide. Gastrin exerts its function through G-protein-coupled receptor called the cholecystokinin (CCK) or CCK-B receptor (CCK-BR)[1].

  • CAS Number: 39024-57-2
  • MF: C98H126N20O31
  • MW: 2080.16000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-D-Allylglycine dicyclohexylamine salt

Boc-D-Gly(allyl)-OH.DCHA is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 221352-64-3
  • MF: C22H40N2O4
  • MW: 396.564
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Trachelogenin 4′-O-β-gentiobioside

Trachelogenin 4′-O-β-gentiobioside, a lignan, can be isolated from the leaves and stems of clover[1][2].

  • CAS Number: 106647-13-6
  • MF: C33H44O17
  • MW: 712.7
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

MLS-0315848 hydrochloride

ML095 is a biochemical inhibitor of PLAP. ML095 is useful to elucidate the key biological functions and natural substrates of human PLAP[1].

  • CAS Number: 1135318-57-8
  • MF: C13H15ClN2O3
  • MW: 282.72
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A