ARD-69

Modify Date: 2025-08-26 22:15:32

ARD-69 Structure
ARD-69 structure
Common Name ARD-69
CAS Number 2316837-10-0 Molecular Weight 1129.82
Density N/A Boiling Point N/A
Molecular Formula C62H74ClFN8O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ARD-69


ARD-69 (compound 34) is a potent PROTAC androgen receptor degrader. ARD-69 induces degradation of androgen receptor (AR) protein in AR-positive prostate cancer cell lines. ARD-69 suppresses AR-regulated gene expression[1].

 Names

Name ARD-69

 ARD-69 Biological Activity

Description ARD-69 (compound 34) is a potent PROTAC androgen receptor degrader. ARD-69 induces degradation of androgen receptor (AR) protein in AR-positive prostate cancer cell lines. ARD-69 suppresses AR-regulated gene expression[1].
Related Catalog
Target

Androgen receptor (AR)[1] PROTAC[1]

References

[1]. Han X, et al. Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer. J Med Chem. 2019 Jan 10.

 Chemical & Physical Properties

Molecular Formula C62H74ClFN8O7S
Molecular Weight 1129.82
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