ARD-69

Modify Date: 2023-04-21 13:02:23

ARD-69 structure	Common Name	ARD-69
	CAS Number	2316837-10-0	Molecular Weight	1129.82
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆₂H₇₄ClFN₈O₇S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ARD-69

ARD-69 (compound 34) is a potent PROTAC androgen receptor degrader. ARD-69 induces degradation of androgen receptor (AR) protein in AR-positive prostate cancer cell lines. ARD-69 suppresses AR-regulated gene expression[1].

Name	ARD-69

Description	ARD-69 (compound 34) is a potent PROTAC androgen receptor degrader. ARD-69 induces degradation of androgen receptor (AR) protein in AR-positive prostate cancer cell lines. ARD-69 suppresses AR-regulated gene expression[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Signaling Pathways >> Others >> Androgen Receptor
Target	Androgen receptor (AR)[1] PROTAC[1]
References	[1]. Han X, et al. Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer. J Med Chem. 2019 Jan 10.

Molecular Formula	C₆₂H₇₄ClFN₈O₇S
Molecular Weight	1129.82

ARD-69

Use of ARD-69

Names

ARD-69 Biological Activity

Chemical & Physical Properties