157974-36-2

157974-36-2 structure

Name: Furosine dihydrochloride
Chemical Name: N6-[2-(2-Furyl)-2-oxoethyl]-L-lysine dihydrochloride
CAS Number: 157974-36-2
Molecular Formula: C₁₂H₂₀Cl₂N₂O₄
Molecular Weight: 327.204
Catalog: Research Areas Metabolic Disease
Create Date: 2018-06-23 00:06:02
Modify Date: 2024-01-06 09:39:08
Furosine dihydrochloride, an amino acid derivative, is an important chemical marker of early-stage Maillard reactions. Furosine dihydrochloride is closely related to a variety of diseases such as diabetes[1][2].

Name	N6-[2-(2-Furyl)-2-oxoethyl]-L-lysine dihydrochloride
Synonyms	L-Lysine, N6-[2-(2-furanyl)-2-oxoethyl]-, hydrochloride (1:2) N6-[2-(2-Furyl)-2-oxoethyl]-L-lysine dihydrochloride

Description	Furosine dihydrochloride, an amino acid derivative, is an important chemical marker of early-stage Maillard reactions. Furosine dihydrochloride is closely related to a variety of diseases such as diabetes[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vitro	Furosine could degrade slowly to form many different advanced glycation end products (AGEs). Partial AGEs have been proven to be closely related to a variety of diseases, such as diabetes, and a high amount of AGEs in human bodies is considered harmful[1].
References	[1]. Li Y, et, al. Qualitative and quantitative analysis of furosine in fresh and processed ginsengs. J Ginseng Res. 2018 Jan;42(1):21-26. [2]. Poojary MM, et, al. Liquid chromatography quadrupole-Orbitrap mass spectrometry for the simultaneous analysis of advanced glycation end products and protein-derived cross-links in food and biological matrices. J Chromatogr A. 2020 Mar 29;1615:460767.