Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Diethyl aspartate

Diethyl aspartate is an aspartic acid derivative[1].

  • CAS Number: 43101-48-0
  • MF: C8H15NO4
  • MW: 189.20900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sennoside D

Sennoside D is an anthraquinone glycoside, found in leaves and pods of Senna (Cassia angustifolia)[1].

  • CAS Number: 37271-17-3
  • MF: C42H40O19
  • MW: 848.756
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 1130.3±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 344.4±27.8 °C

Beauveriolide I

Beauveriolide I is the metabolite of Entomopathogenic Fungi Beauveria sp.. Beauveriolide I (1) exhibits moderate insecticidal activities against Spodoptera litura and Callosobruchus chinensis[1].

  • CAS Number: 154491-55-1
  • MF: C27H41N3O5
  • MW: 487.63200
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BDP 581/591 alkyne

BDP 581/591 alkyne is a moderately hydrophobic borondipyrromethene fluorophore.

  • CAS Number: 2006345-34-0
  • MF: C25H22BF2N3O
  • MW: 429.27
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

S07-2001

S07-2001 is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 2.08 μM. S07-2001 enhances the activity of Doxorubicin against cancer cells. S07-2001 has potential as a chemotherapeutic potentiator for cancer drug resistance[1].

  • CAS Number: 1197904-57-6
  • MF: C15H17N3O4S
  • MW: 335.38
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(2R)-Octyl-α-hydroxyglutarate

(2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a modified form of D-isomer 2-Hydroxyglutarate.

  • CAS Number: 1391194-67-4
  • MF: C13H24O5
  • MW: 260.327
  • Catalog: Cancer
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 420.5±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 152.3±19.4 °C

N-(2,4-DINITROPHENYL)-DL-THREONINE

N-(2,4-Dinitrophenyl)-DL-threonine is a threonine derivative[1].

  • CAS Number: 14401-07-1
  • MF: C10H11N3O7
  • MW: 285.21000
  • Catalog: Others
  • Density: 1.629g/cm3
  • Boiling Point: 572ºC at 760 mmHg
  • Melting Point: 154ºC
  • Flash Point: 299.7ºC

1-Chloro-4-methoxybenzene-d4

1-Chloro-4-methoxybenzene-d4 is the deuterium labeled 1-Chloro-4-methoxybenzene[1].

  • CAS Number: 1219804-86-0
  • MF: C7H7ClO
  • MW: 142.583
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 184.4±13.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 78.3±0.0 °C

GF 15

GF 15 is a potent inhibitor of centrosomal clustering in tumor cells.

  • CAS Number: 888042-13-5
  • MF: C23H21ClO6
  • MW: 428.86
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4′,5,7-Triacetoxyflavone

Apigenin triacetate is a metabolite of F. graminearum. Apigenin triacetate can be downregulated in F. graminearum by chitosan treatment. Apigenin triacetate derives from apigenin[1].

  • CAS Number: 3316-46-9
  • MF: C21H16O8
  • MW: 396.35
  • Catalog: Others
  • Density: 1.356g/cm3
  • Boiling Point: 569.5ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 249.6ºC

Difucosyllacto-N-neohexaose

Difucosyllacto-N-neohexaose is an oligosaccharide that can be isolated from human milk[1].

  • CAS Number: 64396-27-6
  • MF: C52H88N2O39
  • MW: 1365.25
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

embramine hydrochloride

Embramine (hydrochloride) is a monoethanolamine used as an antihistamine and anticholinergic[1].

  • CAS Number: 13977-28-1
  • MF: C18H23BrClNO
  • MW: 384.73800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 405.8ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 199.2ºC

2,4,5,6-Tetraaminopyrimidine

2,4,5,6-Tetraaminopyrimidine is a coloring agent extracted from patent US20170258692A1, compound A[1].

  • CAS Number: 1004-74-6
  • MF: C4H8N6
  • MW: 140.14700
  • Catalog: Others
  • Density: 1.648g/cm3
  • Boiling Point: 563.9ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: N/A

Ala-Arg-Arg-Pro-Glu-Gly-Arg-Thr-Trp-Ala-Gln-Pro-Gly-Tyr

Ala-Arg-Arg-Pro-Glu-Gly-Arg-Thr-Trp-Ala-Gln-Pro-Gly-Tyr is a peptide. Ala-Arg-Arg-Pro-Glu-Gly-Arg-Thr-Trp-Ala-Gln-Pro-Gly-Tyr can easily be formed with more than one positive charge[1].

  • CAS Number: 309247-45-8
  • MF: C72H109N25O20
  • MW: 1644.79
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

His-Gly

(S)-2-(2-Amino-3-(1H-imidazol-4-yl)propanamido)acetic acid is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 2578-58-7
  • MF: C8H12N4O3
  • MW: 212.20600
  • Catalog: Others
  • Density: 1.434g/cm3
  • Boiling Point: 687.4ºC at 760mmHg
  • Melting Point: 180-182℃
  • Flash Point: 369.5ºC

Ala-Ala-OMe

Ala-Ala-OMe is adipeptide derivative.

  • CAS Number: 24326-09-8
  • MF: C7H14N2O3
  • MW: 174.20
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N3-L-Cys(Trt)-OH (CHA)

N3-L-Cys(Trt)-OH (CHA) is a click chemistry reagent containing an azide group.

  • CAS Number: 1286670-90-3
  • MF: C28H32N4O2S
  • MW: 488.64
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

VIP (1-12), human, porcine, rat, ovine

VIP (1-12), human, porcine, rat, ovine is a vasoactive intestinal peptide (VIP) fragment. VIP (1-12), human, porcine, rat, ovine is a ligand for the CD4 (T4)/human immunodeficiency virus receptor[1][2].

  • CAS Number: 120928-03-2
  • MF: C61H88N18O22
  • MW: 1425.46000
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

L-Ornithine L-aspartate salt

L-Ornithine L-aspartate is a stable salt of two natural nonessential L-amino acids: ornithine and aspartic acid. L-Ornithine L-aspartate lowers blood ammonia concentration and to eliminate symptoms of hepatic encephalopathy associated with liver cirrhosis[1].

  • CAS Number: 3230-94-2
  • MF: C9H19N3O6
  • MW: 265.264
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: 308.7ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 140.5ºC

Etigilimab

Etigilimab (OMP-313M32), a humanized IgG1 monoclonal antibody, blocks TIGIT interaction with PVR (CD155; poliovirus receptor) and inhibits downstream signalling with target cell killing[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Methylethanamine-d5

N-Methylethanamine-d5 is the deuterium labeled N-Methylethanamine[1].

  • CAS Number: 1219804-73-5
  • MF: C3H4D5N
  • MW: 64.141
  • Catalog: Others
  • Density: 0.7±0.1 g/cm3
  • Boiling Point: 36.7±3.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: -37.5±8.8 °C

3-Methylpyrazole

3-Methylpyrazole is used as a nitrification inhibitor of nitrification in soil[1].

  • CAS Number: 1453-58-3
  • MF: C4H6N2
  • MW: 82.104
  • Catalog: Metabolic Disease
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 204.0±0.0 °C at 760 mmHg
  • Melting Point: 36 - 37ºC
  • Flash Point: 87.4±11.7 °C

Sincalide ammonium

Sincalide ammonium (Cholecystokinin octapeptide ammonium) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide ammonium is an agent that promotes gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. The hepatobiliary physiologic effect of Sincalide ammonium is to increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum[1][2].

  • CAS Number: 70706-98-8
  • MF: C49H65N11O16S3
  • MW: 1160.30
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

α-Cyanopyridine-d4

α-Cyanopyridine-d4 is the deuterium labeled α-Cyanopyridine[1].

  • CAS Number: 1219795-17-1
  • MF: C6H4N2
  • MW: 104.109
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 225.5±13.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 89.4±0.0 °C

D-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid

(R)-1,2,3,4-Tetrahydro-3-isoquinolinecarboxylic acid is a constrained Phe analogue which can fold into a beta-bend and a helical structure, and to adopt a preferred side-chain disposition in the peptide.IC50 value:Target: Three Tic-containing (Tic = 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid) model peptides were synthesized to assess the tendency of this constrained Phe analogue to fold into a beta-bend and a helical structure, and to adopt a preferred side-chain disposition. The results of the solution conformational analysis, performed by using Fourier transform infrared absorption and 1H nuclear magnetic resonance, indicate that in chloroform the -Aib-D-Tic-Aib-, -(Aib)2-D-Tic-(Aib)2-, and -L-Pro-D-Tic- sequences fold into intramolecularly H-bonded forms to a great extent. An X-ray diffraction analysis on p-BrBz-(Aib)2-DL-Tic-(Aib)2-OMe monohydrate and p-BrBz-L-Pro-D-Tic-NHMe allows us to conclude that, while the pentapeptide methylester forms an incipient (distorted) 3(10)-helix, the dipeptide methylamide adopts a type-II beta-bend conformation. In both cases, the D-Tic side-chain conformation is D, gauche(-). The implications for the use of the Tic residue in designing conformationally restricted analogues of bioactive peptides are briefly discussed.

  • CAS Number: 103733-65-9
  • MF: C10H11NO2
  • MW: 177.200
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 372.0±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 178.8±27.9 °C

Carbaryl-(methyl-d3)

Carbaryl-d3 is the deuterium labeled N6-(carboxymethyl)-L-lysine[1].

  • CAS Number: 1433961-56-8
  • MF: C12H8D3NO2
  • MW: 204.24
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

viquidil

Viquidil (LM 192) is a cerebral vasodilator agent [1].

  • CAS Number: 84-55-9
  • MF: C20H24N2O2
  • MW: 324.41700
  • Catalog: Cardiovascular Disease
  • Density: 1.125g/cm3
  • Boiling Point: 493.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 252ºC

Deoxyflindissone

Deoxyflindissone (Compound 13) is a triterpenoidcompound. Deoxyflindissone is isolated from natural Cornus walteri.Deoxyflindissone has significant cytotoxic activity[1].

  • CAS Number: 107176-31-8
  • MF: C30H46O2
  • MW: 438.68500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

293P-1

293P-1 is a peptide with tissue-specific homing properties. 293P-1 is specific for hepatocytes with sequences of SNNNVRPIHIWP[1].

  • CAS Number: 1465746-23-9
  • MF: C65H99N21O17
  • MW: 1446.61
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BPK-25

BPK-25, an active acrylamide, promotes degradation of nucleosome remodeling and deacetylation (NuRD) complex proteins by a post-translational mechanism involving covalent protein engagement. BPK-25 inhibits TMEM173 activation by the cyclic dinucleotide ligand cGAMP[1].

  • CAS Number: 2305052-86-0
  • MF: C21H17ClN4O2
  • MW: 392.84
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A