1197904-57-6

1197904-57-6 structure

Name: S07-2001
Chemical Name: S07-2001
CAS Number: 1197904-57-6
Molecular Formula: C₁₅H₁₇N₃O₄S
Molecular Weight: 335.38
Catalog: Research Areas Cancer
Create Date: 2022-08-18 15:37:30
Modify Date: 2024-09-17 14:24:42
S07-2001 is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 2.08 μM. S07-2001 enhances the activity of Doxorubicin against cancer cells. S07-2001 has potential as a chemotherapeutic potentiator for cancer drug resistance[1].

Name	S07-2001

Description	S07-2001 is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 2.08 μM. S07-2001 enhances the activity of Doxorubicin against cancer cells. S07-2001 has potential as a chemotherapeutic potentiator for cancer drug resistance[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	S07-2001 (50 μM) reduces 27% of MCF-7 cell viability administrated with Doxorubicin[1].
References	[1]. Siyu He, et al. Discovery of Novel Aldo-Keto Reductase 1C3 Inhibitors as Chemotherapeutic Potentiators for Cancer Drug Resistance. ACS Med. Chem. Lett. Jun 2022.

Molecular Formula	C₁₅H₁₇N₃O₄S
Molecular Weight	335.38