Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

1-Palmitoyl-sn-glycerol 3-phosphate

1-Palmitoyl-sn-glycerol 3-phosphate (1-P-GPA) is an endogenous metabolite. 1-Palmitoyl-sn-glycerol 3-phosphate can be used for the research of non‐alcoholic fatty liver disease[1].

  • CAS Number: 7220-34-0
  • MF: C19H39O7P
  • MW: 410.48
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

INT

INT(Iodonitrotetrazolium chloride) is used in various dehydrogenase colorimetric analysis of the electron acceptor.

  • CAS Number: 146-68-9
  • MF: C19H13ClIN5O2
  • MW: 505.696
  • Catalog: Biochemical Assay Reagents
  • Density: N/A
  • Boiling Point: 567.5ºC at 760 mmHg
  • Melting Point: 240 °C (dec.)(lit.)
  • Flash Point: 297ºC

Rosthornin A

Rosthornin A is a ent-kaurene diterpenoid compound, isolated from the ether extract of the dried leaves of Rabdosia rosthornii[1].

  • CAS Number: 125164-55-8
  • MF: C22H32O5
  • MW: 376.487
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 513.3±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 173.8±23.6 °C

Chlorpropham-d7

Chlorpropham-d7 is the deuterium labeled Chlorpropham[1]. Chlorpropham is a carbamate herbicide and plant growth regulator. Chlorpropham inhibits mitosis and cell division by interfering with the organisation of the spindle microtubules[2][3].

  • CAS Number: 2140327-49-5
  • MF: C10H5D7ClNO2
  • MW: 220.70
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Terrestrosin K

Terrestrosin K, a steroidal saponin from Tribulus terrestris L., has potential to treat cardiovascular and cerebrovascular diseases[1].

  • CAS Number: 193605-07-1
  • MF: C51H82O24
  • MW: 1079.182
  • Catalog: Cardiovascular Disease
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(R)-CE3F4

(R)-CE3F4 is a potent and selective inhibitor of exchange protein directly activated by cAMP isoform 1 (Epac1), with an IC50 of 4.2 μM, with 10-fold selectivity for Epac1 over Epac2 (IC50, 44 μM). (R)-CE3F4 is more potent than racemic CE3F4 and (S)-CE3F4[1].

  • CAS Number: 1593478-56-8
  • MF: C11H10Br2FNO
  • MW: 351.01
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(E)-2,3-Dibromo-2-butenedioic acid

(E)-2,3-Dibromo-2-butenedioic acid is one of brominated haloacids, which are the drinking water disinfection byproducts (DBPs)[1].

  • CAS Number: 608-38-8
  • MF: C4H2Br2O4
  • MW: 273.86400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isomangiferin

Isomangiferin, a natural product, is reported to have antiviral activity.

  • CAS Number: 24699-16-9
  • MF: C19H18O11
  • MW: 422.340
  • Catalog: Infection
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 798.8±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 288.2±26.4 °C

Brevianamide R

Brevianamide R (compound 4) is an alkaloid isolated from Aspergillus versicolor on fermented rice[1].

  • CAS Number: 1259316-09-0
  • MF: C22H25N3O3
  • MW: 379.45
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Dobupride

Dobupride is a novel gastroprokinetic drug.

  • CAS Number: 106707-51-1
  • MF: C20H30ClN3O4
  • MW: 411.92300
  • Catalog: Others
  • Density: 1.26g/cm3
  • Boiling Point: 544.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 283.1ºC

Ethane,2,2-dichloro-1,1-difluoro-1-methoxy-

Methoxyflurane is a halogenated volatile anaesthetic agent with potent analgesic effects at sub-anaesthetic doses. Methoxyflurane widely used as an open-circuit anaesthetic in small laboratory animals for several decades. Methoxyflurane has the risk of nephrotoxicity[1][2].

  • CAS Number: 76-38-0
  • MF: C3H4Cl2F2O
  • MW: 164.96600
  • Catalog: Others
  • Density: 1.4262
  • Boiling Point: 103 °C
  • Melting Point: -36°C
  • Flash Point: 37°C

Taxifolin 7-O-rhamnoside

Taxifolin 7-O-rhamnoside (Taxifolin 7-O-α-L-rhamnoside) is a flavonoid isolated from Hypericum japonicum.

  • CAS Number: 137592-12-2
  • MF: C21H22O11
  • MW: 450.393
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 832.5±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 293.9±27.8 °C

2-(1-naphthyl)-5-phenyloxazole

2-(Naphthalen-1-yl)-5-phenyloxazole (α-NPO) is an organic fluorescent dye. 2-(Naphthalen-1-yl)-5-phenyloxazole has a nitrogen atom in its structure that can interfere with the nitrogen content from the amination step[1].

  • CAS Number: 846-63-9
  • MF: C19H13NO
  • MW: 271.31300
  • Catalog: Others
  • Density: 1.178g/cm3
  • Boiling Point: 451ºC at 760 mmHg
  • Melting Point: 104-106 °C
  • Flash Point: 192.6ºC

H-3-DL-Ala(2-thienyl)-OH

3-(2-Thienyl)-DL-alanine is an alanine derivative[1].

  • CAS Number: 2021-58-1
  • MF: C7H9NO2S
  • MW: 171.217
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 311.3±32.0 °C at 760 mmHg
  • Melting Point: 275-277 °C (dec.)(lit.)
  • Flash Point: 142.1±25.1 °C

Tritoqualine

Tritoqualine is used as a histidine decarboxylase inhibitor.

  • CAS Number: 14504-73-5
  • MF: C26H32N2O8
  • MW: 500.54100
  • Catalog: Inflammation/Immunology
  • Density: 1.296g/cm3
  • Boiling Point: 647.2ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 345.2ºC

KWAR 23

KWAR23 is an anti-human SIRPα antibody. KWAR23 binds human SIRPα with high affinity and disrupts its binding to CD47. KWAR23 shows antitumor activity in combination with tumor-opsonizing antibodies and can be used in cancer immunotherapy research[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-D-Asp(OcHex)-OH

Boc-D-Asp(OcHex)-OH is an aspartic acid derivative[1].

  • CAS Number: 112898-18-7
  • MF: C15H25NO6
  • MW: 315.36200
  • Catalog: Others
  • Density: 1.18g/cm3
  • Boiling Point: 487.2ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 248.4ºC

NHS-NH-(diethylamino)ethyl benzoate

NHS-NH-(diethylamino)ethyl benzoate is a compound that can be used for N-glycan labeling[1].

  • CAS Number: 2050902-45-7
  • MF: C18H23N3O6
  • MW: 377.39
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

D-threo-PPMP hydrochloride

D-threo-PPMP hydrochloride is a potent inhibitor of glucosylceramide (GlcCer) synthase. D-threo-PPMP hydrochloride can block karyokinesis and reduce cyst production[1][2].

  • CAS Number: 139889-65-9
  • MF: C29H51ClN2O3
  • MW: 511.180
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

MDNI-caged-L-glutamate

MDNI-caged-L-glutamate (MDNI-glu) rapidly and efficiently releases glutamate when photolysed (350-365 nm excitation). MDNI-caged-L-glutamate is inactive at neuronal glutamate receptors (up to 200 μM) and stable at neutral pH. MDNI-caged-L-glutamate is activated by laser to evoke a rapid increase in intracellular ca2+ concentration in astrocytes.

  • CAS Number: 864085-92-7
  • MF: C14H16N4O8
  • MW: 368.30
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1b-Benzoyl-8a-cinnamoyl-4a,5a-dihydroxydihydroagarofuran

1b-Benzoyl-8a-cinnamoyl-4a,5a-dihydroxydihydroagarofuran is a sesquiterpenoid isolated from the root bark of Tripterygium hypoglaucum containing a benzoyl and a cinnamoyl group[1].

  • CAS Number: 268541-27-1
  • MF: C31H36O7
  • MW: 520.61
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Aristolone

Aristolone is a sesquiterpene isolated from Aristolochia debilis[1].

  • CAS Number: 25274-27-5
  • MF: C15H22O
  • MW: 218.335
  • Catalog: Cancer
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 308.7±9.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 136.5±9.6 °C

Acetyl tetrapeptide-3

Acetyl tetrapeptide-3 combined with Biochanin A (HY-14595) and Acetyl tetrapeptide-3, can stimulate dermal papilla extracellular matrix (ECM) proteins by increasing hydroxyproline, Collagen Type 3, and laminin, yielding a significant improvement in hair follicle size and hair anchoring[1].

  • CAS Number: 827306-88-7
  • MF: C22H39N9O5
  • MW: 509.602
  • Catalog: Metabolic Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 1075.4±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 604.2±34.3 °C

Isobavachin

Isobavachin, an antioxidant isaolated from Psoralea morisiana with a prenyl group at position 8 of ring A, promotes neuronal differentiation and the potential role of its protein prenylation[1][2].

  • CAS Number: 31524-62-6
  • MF: C20H20O4
  • MW: 324.370
  • Catalog: Neurological Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 558.3±50.0 °C at 760 mmHg
  • Melting Point: 187-188℃
  • Flash Point: 202.1±23.6 °C

3,4-Dichlorophenylalanine

H-Phe(3,4-DiCl)-OH is a phenylalanine derivative[1].

  • CAS Number: 52794-99-7
  • MF: C9H9Cl2NO2
  • MW: 234.079
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 370.6±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 177.9±27.9 °C

Cyanine5 amine hydrochloride

Cyanine5 amine hydrochloride is a potent fluorescent dye. Cyanine5 amine hydrochloride can be reacted with terminal alkynes via a copper-catalyzed click reaction (CuAAC). (λex=646 nm, λem=662 nm)[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Secretin

Secretin (swine), a neuroendocrine hormone, is the first hormone to be identifie and is secreted by S cells that are localized primarily in the mucosa of the duodenum. Secretin also is a 27-amino acid peptide, which acts on secretin receptors. Secretin is expressed by cells in all mature enteroendocrine cell subsets and can be prompted by fatty acids. Secretin stimulates the secretion of pancreatic water and bicarbonate. Secretin exerts various effects in organs, can be used for the research of digestive system, central nervous system and energy metabolism[1][2].

  • CAS Number: 17034-35-4
  • MF: C130H220N44O41
  • MW: 3055.41000
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ikarugamycin

Ikarugamycin is an antibiotic and a inhibitor of clathrin-mediated endocytosis (CME)[1].

  • CAS Number: 36531-78-9
  • MF: C29H38N2O4
  • MW: 478.62
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 741.9±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 402.5±32.9 °C

1,2,3-Tridocosahexaenoyl Glycerol

Tridocosahexaenoin is a triacylglycerol with anti-autoxidative properties[1].

  • CAS Number: 11094-59-0
  • MF: C69H98O6
  • MW: 1023.51
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-(1,4-Dihydro-2-pyrazinyl)ethanone

Acetylpyrazine (2-Acetylpyrazine) is fused to form many polycyclic compounds, as useful structures in pharmaceuticals and perfumes. Acetylpyrazine is a component of the folates (vitamin B compounds) [1].

  • CAS Number: 22047-25-2
  • MF: C6H6N2O
  • MW: 124.141
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 249.0±40.0 °C at 760 mmHg
  • Melting Point: 75-78 °C
  • Flash Point: 121.9±27.5 °C