(R)-CE3F4

Modify Date: 2024-01-10 19:19:57

(R)-CE3F4 Structure
(R)-CE3F4 structure
Common Name (R)-CE3F4
CAS Number 1593478-56-8 Molecular Weight 351.01
Density N/A Boiling Point N/A
Molecular Formula C11H10Br2FNO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (R)-CE3F4


(R)-CE3F4 is a potent and selective inhibitor of exchange protein directly activated by cAMP isoform 1 (Epac1), with an IC50 of 4.2 μM, with 10-fold selectivity for Epac1 over Epac2 (IC50, 44 μM). (R)-CE3F4 is more potent than racemic CE3F4 and (S)-CE3F4[1].

 Names

Name (R)-CE3F4

 (R)-CE3F4 Biological Activity

Description (R)-CE3F4 is a potent and selective inhibitor of exchange protein directly activated by cAMP isoform 1 (Epac1), with an IC50 of 4.2 μM, with 10-fold selectivity for Epac1 over Epac2 (IC50, 44 μM). (R)-CE3F4 is more potent than racemic CE3F4 and (S)-CE3F4[1].
Related Catalog
References

[1]. Courilleau D, et al. The (R)-enantiomer of CE3F4 is a preferential inhibitor of human exchange protein directly activated by cyclic AMP isoform 1 (Epac1). Biochem Biophys Res Commun. 2013 Oct 25;440(3):443-8.

 Chemical & Physical Properties

Molecular Formula C11H10Br2FNO
Molecular Weight 351.01
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