Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

(S)-2-AMINO-5-METHOXY-5-OXOPENTANOIC ACID HYDROCHLORIDE

H-Glu(OMe)-OH hydrochloride is a protonated glutamic acid derivative[1].

  • CAS Number: 3077-51-8
  • MF: C6H12ClNO4
  • MW: 197.61700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 316.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 145ºC

StilbosteMin N

Stilbostemin N can be isolated from ated from the rhizomes of D. japonica[1].

  • CAS Number: 1000676-45-8
  • MF: C16H18O3
  • MW: 258.31
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 742.2±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 402.7±32.9 °C

Anti-inflammatory agent 36

Anti-inflammatory agent 36 is an anti-inflammatory agent. Anti-inflammatory agent 36 inhibits LPS-induced macrophage activation[1].

  • CAS Number: 2293951-01-4
  • MF: C25H27NO7
  • MW: 453.48
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-MethoxyPinocembroside

5-MethoxyPinocembroside is a flavonoid isolated from Penthorumchinense Pursh.

  • CAS Number: 1450878-89-3
  • MF: C22H24O9
  • MW: 432.42
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

nitrilotriacetic acid

Nitrilotriacetic acid is an aminotricarboxylic acid. Nitrilotriacetic acid can be used as a chelating agent, forming coordination compounds with metal ions[1].

  • CAS Number: 139-13-9
  • MF: C6H9NO6
  • MW: 191.139
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 498.2±40.0 °C at 760 mmHg
  • Melting Point: 245 °C (dec.)(lit.)
  • Flash Point: 255.1±27.3 °C

N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium

N7-Methyl-guanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium is a dinucleotide cap analog that can be used for in vitro RNA transcription[1].

  • CAS Number: 75252-10-7
  • MF: C21H35N12O17P3
  • MW: 820.49
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Diethyl aminoethyl hexanoate citrate

Diethyl aminoethyl hexanoate citrate is a compound that is widely used as a plant growth regulator.

  • CAS Number: 220439-24-7
  • MF: C18H33NO9
  • MW: 407.45600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Glucagon (19-29) (human, rat, porcine) trifluoroacetate salt

Glucagon (19-29), human is a potent and efficient inhibitor of insulin secretion.

  • CAS Number: 64790-15-4
  • MF: C61H89N15O18S
  • MW: 1352.51000
  • Catalog: Peptides
  • Density: 1.339 g/cm3
  • Boiling Point: 1828.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 1059.6ºC

Dornase alfa

Dornase alfa (rhDNase) is a recombinant human deoxyribonuclease I (rhDNase), an enzyme which selectively cleaves DNA. Dornase alfa hydrolyzes the DNA present in sputum/mucus and reduces viscosity in the lungs, promoting improved clearance of secretions. Dornase alfa plays an important role in cystic fibrosis[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Luvangetin

Luvangetin is a coumarin that can be isolated from Zanthoxylum avicennae[1].

  • CAS Number: 483-92-1
  • MF: C15H14O4
  • MW: 258.27
  • Catalog: Others
  • Density: 1.225g/cm3
  • Boiling Point: 431.8ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 193.9ºC

LGLLLRHLRHHSNLLANI

LGLLLRHLRHHSNLLANI (B18) is an 18 amino acid peptide. LGLLLRHLRHHSNLLANI derives from the membrane-associated protein binding. LGLLLRHLRHHSNLLANI shows a high affinity for Cu(2+) ions[1].

  • CAS Number: 222557-92-8
  • MF: C94H160N32O22
  • MW: 2090.48
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4,4'-Dihydroxybiphenyl-d8

4,4'-Dihydroxybiphenyl-d8 is the deuterium labeled 4,4'-Dihydroxybiphenyl[1].

  • CAS Number: 612480-60-1
  • MF: C12H2D8O2
  • MW: 194.25600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Aristola-1(10),8-dien-2-one

Aristola-1(10),8-dien-2-one is a sesquiterpene compound that can be isolated from rhizome of Nardostachys chinensis of Valerianaceae[1].

  • CAS Number: 22391-34-0
  • MF: C15H20O
  • MW: 216.32
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isoguaiacin

Isoguaiacin is a natural product[1].

  • CAS Number: 78341-26-1
  • MF: C20H24O4
  • MW: 328.4
  • Catalog: Others
  • Density: 1.151±0.06 g/cm3(Predicted)
  • Boiling Point: 484.5±45.0 °C(Predicted)
  • Melting Point: 198-200 °C
  • Flash Point: N/A

Coumarin

Coumarin is the primary bioactive ingredient in Radix Glehniae, named Beishashen in China, which possesses many pharmacological activities, including anticancer, anti-inflammation and antivirus activities.

  • CAS Number: 91-64-5
  • MF: C9H6O2
  • MW: 146.143
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 298.0±0.0 °C at 760 mmHg
  • Melting Point: 68-73 °C(lit.)
  • Flash Point: 118.3±16.1 °C

Miroestrol

Miroestrol is a highly active phytoestrogen. Miroestrol can produce mammogenic effect. Miroestrol exhibits bone loss prevention and neuroprotective in ovariectomized mice. Miroestrol also can reduce cancer risk[1][2][3][4].

  • CAS Number: 2618-41-9
  • MF: C20H22O6
  • MW: 358.38500
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

NIOCH 14

NIOCH 14 is a antiviral agent and a pro-drug. NIOCH 14 has antiviral activity against orthopoxviruses. NIOCH 14 can significantly lower proportions of infected mice, and virus production levels in the lungs. NIOCH 14 can be used for researching anti-smallpox[1][2].

  • CAS Number: 1268015-38-8
  • MF: C19H17F3N2O4
  • MW: 394.34
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Furobufen

Furobufen, an anti-inflammatory agent, produces antiarthritic, antipyretic effects. Furobufen has an analgesic effect in inflamed tissue[1].

  • CAS Number: 38873-55-1
  • MF: C16H12O4
  • MW: 268.26400
  • Catalog: Inflammation/Immunology
  • Density: 1.343g/cm3
  • Boiling Point: 509.8ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 262.1ºC

Apovincamine

Apovincamine (cis-Apovincamine) is an indole alkaloid isolated from the Malaysian Alstonia pneumatophora (Apocynaceae). Apovincamine shows anti-melanogenesis activity[1].

  • CAS Number: 4880-92-6
  • MF: C21H24N2O2
  • MW: 336.42700
  • Catalog: Others
  • Density: 1.3g/cm3
  • Boiling Point: 405.7ºC at 760mmHg
  • Melting Point: 160-162℃
  • Flash Point: 199.1ºC

17:0-22:4 PC-d5

17:0-22:4 PC-d5 is deuterium labeled 17:0-22:4 PC.

  • CAS Number: 2342575-43-1
  • MF: C47H81D5NO8P
  • MW: 829.19
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Mycophenolic acid D3

Mycophenolic acid D3 is deuterium labeled Mycophenolic acid, which is an an immunosuppresant drug and has potent anti-proliferative activity.

  • CAS Number: 1185242-90-3
  • MF: C17H17D3O6
  • MW: 323.35600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 132-134°C
  • Flash Point: 2℃

OSMI-3

OSMI-3 (Compound 2b) is a potent, long-lasting, and cell-permeable O-linked N-acetylglucosamine transferase (OGT) inhibitor. Cells contain a large nuclear pool of partially spliced OGT transcript, and OSMI-3 increases detained intron splicing in cells[1].

  • CAS Number: 2260791-13-5
  • MF: C32H35N3O9S2
  • MW: 669.77
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Coelenterazine 400a (hydrochloride)

Coelenteramine 400a (Coelenterazine 400a) hydrochloride, a derivative of Coelenterazine, is a Renilla luciferase (RLuc) substrate. In the presence of Coelenteramine 400a hydrochloride, RLuc can emit blue light at 395 nm[1][2]. Coelenteramine 400a hydrochloride will causes color change in the bioluminescence reaction of Rluc by replacing the sulfur and oxygen heteroatoms of the methylene bridge. Coelenteramine 400a hydrochloride provides higher signal resolution and can be used in the research of bioluminescence resonance energy transfer (BRET)[3].

  • CAS Number: 2320429-05-6
  • MF: C26H22ClN3O
  • MW: 427.925
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

13-Oxopodocarp-8(14)-en-15-oic acid

13-Keto-8(14)-Podocarpen-18-oic acid (compound 16) is a compound isolated from Pinus massoniana Lamb[1].

  • CAS Number: 63976-69-2
  • MF: C17H24O3
  • MW: 276.37
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 444.4±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 236.7±25.2 °C

Azacyclonol

Azacyclonol, also known as γ-pipradol, is a drug used to diminish hallucinations in psychotic individuals.Target: OthersAzacyclonol is a drug which is a so-called ataractive, or agent which diminishes hallucinations in psychotic individuals. The formation of Azacyclonol in human intestinal microsomes is linear with respect to time up to 60 min. The rates of formation of Azacyclonol increases linearly with microsomal protein concentration up to 2 mg/mL. The apparent Km and Vmax values of Azacyclonol are 0.82 μM and 60 pmol/min/mg protein in microsomes from human liver [1]. The formation of Azacyclonol and terfenadine alcohol from terfenadine is confirmed to be catalyzed predominantly by CYP3A(4) isozyme, and the ratio of the rate of terfenadine alcohol formation to that of Azacyclonol is 3:1 [2]. The amount of Azacyclonol eliminated renally increases on average 2-fold after rifampin dosing [3].

  • CAS Number: 115-46-8
  • MF: C18H21NO
  • MW: 267.365
  • Catalog: Neurological Disease
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 445.5±40.0 °C at 760 mmHg
  • Melting Point: 160-163 °C
  • Flash Point: 142.0±18.0 °C

CuATSP

CuATSP, a potent inhibitor of ferroptotic cell death, is almost 20-fold more potent than CuATSM.

  • CAS Number: 68341-12-8
  • MF: C18H18CuN6S2
  • MW: 446.05
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Artemetin

Artemitin is a flavonol found in Laggera pterodonta (DC.) Benth., with antioxidative, anti-inflammatory, and antiviral activity[1].

  • CAS Number: 479-90-3
  • MF: C20H20O8
  • MW: 388.368
  • Catalog: Infection
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 588.8±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 208.9±23.6 °C

(Val²)-Amyloid β-Protein (1-6) trifluoroacetate salt

(Val2)-Amyloid β-Protein (1-6) is a biologically active peptide.

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Lipopolysaccharides, Escherichiacoli (11C)

Lipopolysaccharides, Escherichiacoli (11C) consists of a hydrophobic lipid A, a core oligosaccharide (core OS), and a distal polysaccharide (O-PS). Lipopolysaccharides, Escherichiacoli (11C) can be used to induce inflammation[1].

  • CAS Number: 93572-42-0
  • MF:
  • MW:
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BODIPY 530/550 NHS ester

BODIPY 530/550 NHS ester can be used for the stain of protein. BODIPY 530/550 NHS ester can be used for fluorescence OIM (oblique illumination microscopic) image[1].

  • CAS Number: 216961-93-2
  • MF: C28H22BF2N3O4
  • MW: 513.30
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A