Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

(Ser(tBu)6,AzaGly10)-LHRH

(Ser(tBu)6,Azagly10)-LHRH is a potent aza-GLY analog[1].

  • CAS Number: 184686-52-0
  • MF: C59H84N18O14
  • MW: 1269.411
  • Catalog: Endocrinology
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

primulic acid 2

Primulic acid II is a saponin isolated from root extract of Primula sp[1].

  • CAS Number: 208599-88-6
  • MF: C59H96O27
  • MW: 1237.38000
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isoxazole

Isoxazole is a drug scaffold that can be used to develop new drugs with various biological activities (e.g. anti-microbial, anti-viral, anti-cancer, anti-inflammatory, immunomodulatory, anti-convulsant or anti-diabetic properties)[1][2].

  • CAS Number: 288-14-2
  • MF: C3H3NO
  • MW: 69.062
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 95.5±9.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 8.9±0.0 °C

Rhodiolin

Rhodiolin is a flavonoid isolated from Rhodiola fastigita[1].

  • CAS Number: 86831-53-0
  • MF: C25H20O10
  • MW: 480.42000
  • Catalog: Others
  • Density: 1.5746g/ml
  • Boiling Point: N/A
  • Melting Point: 235-237℃
  • Flash Point: N/A

Verpasep caltespen

Verpasep caltespen (HspE7) is a recombinant fusion protein derived from Mycobacterium bovis Calmette-Guérin heat shock protein 65 (Hsp65), the C-terminal end of which is covalently linked to the E7 protein of HPV16. Verpasep caltespen can be used in the study of precancerous and cancerous lesions caused by human papillomavirus (HPV) [1][2].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cicloxilic acid

Cicloxilic acid is a biologically active agent.

  • CAS Number: 57808-63-6
  • MF: C13H16O3
  • MW: 220.26400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Decursidate

Decursidate is an active compound. Decursidate can prolong thrombin time[1].

  • CAS Number: 272122-56-2
  • MF: C18H18O6
  • MW: 330.332
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 587.1±50.0 °C at 760 mmHg
  • Melting Point: 70-71℃
  • Flash Point: 214.9±23.6 °C

Tristin

Tristin is a bibenzyl derivatives. Tristin is a nature product isolated from Dendrobii Herba (stems of Dendrobium spp.). Tristin has antioxidative activity[1].

  • CAS Number: 139101-67-0
  • MF: C15H16O4
  • MW: 260.29
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 452.9±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 227.7±25.9 °C

boc-(r)-3-thienylglycine

Boc-(R)-3-thienylglycine is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 33130-97-1
  • MF: C11H15NO4S
  • MW: 257.30600
  • Catalog: Others
  • Density: 1.273g/cm3
  • Boiling Point: 425.2ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 210.9ºC

Sodium hexadecyl sulfate-d33

Sodium hexadecyl sulfate-d33 is the deuterium labeled Sodium hexadecyl sulfate[1].

  • CAS Number: 2708287-31-2
  • MF: C16HD33NaO4S
  • MW: 378.70
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

prop-2-enyl N-[9-chloro-7-(prop-2-enoxycarbonylamino)acridin-2-yl]carbamate

2,7-Bis(alloxycarbonylamino)-9-chloroacridine can be used as a fluorescent label.

  • CAS Number: 887353-21-1
  • MF: C21H18ClN3O4
  • MW: 411.83800
  • Catalog: Others
  • Density: 1.382g/cm3
  • Boiling Point: 530ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 274.3ºC

Boc-D-Trp(For)-OH

Boc-D-Trp(For)-OH, containing the amino acid tryptophan, is synthesized by the ammonolysis of Boc-protected D-alanine, followed by cyclization to form a dipeptide with ninhydrin. Boc-D-Trp(For)-OH has pharmacological properties, including inhibition of growth hormone release, induction of sleep and antiinflammatory[1][2].

  • CAS Number: 64905-10-8
  • MF: C17H20N2O5
  • MW: 332.35100
  • Catalog: Inflammation/Immunology
  • Density: 1.26g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

meso-CF3-BODIPY 2

meso-CF3-BODIPY 2 (CF3-substituted Tetramethyl BODIPY) is a fluorescent dye with the absorption wavelength (λabs) of 553 nm and emission wavelength (λem) of 622 nm. meso-CF3-BODIPY 2 can be used in labeling reagents and photodynamic therapy[1][2].

  • CAS Number: 1642327-22-7
  • MF: C14H14BF5N2
  • MW: 316.08
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Anticancer agent 103

Anticancer agent 103 (Compound 2k) is a potent anticancer agent[1].

  • CAS Number: 2914922-78-2
  • MF: C18H20BrN3O
  • MW: 374.27
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Disodium edetate dihydrate

Ethylenediaminetetraacetic acid (EDTA) disodium dihydrate is a chelating agent used as a protease inhibitor and metal ion scavenger. Ethylenediaminetetraacetic acid disodium dihydrate is used extensively during protein purification. Ethylenediaminetetraacetic acid disodium dihydrate has been shown to be a noneffective molecule on cellulase activity. Ethylenediaminetetraacetic acid disodium dihydrate binds to metals including calcium and facilitates their excretion[1][2].

  • CAS Number: 6381-92-6
  • MF: C10H18N2Na2O10
  • MW: 372.237
  • Catalog: Metabolic Disease
  • Density: 1.01 g/mL at 25 °C
  • Boiling Point: >100 °C
  • Melting Point: 250 °C (dec.)(lit.)
  • Flash Point: 325.2ºC

1,3,5,6-Tetrahydroxyxanthone

1,3,5,6-Tetrahydroxyxanthone is a natural xanthone that can be isolated from Garcinia achachairu Rusby (Clusiaceae) branches. 1,3,5,6-Tetrahydroxyxanthone induces diuresis and saluresis in normotensive and hypertensive rats[1].

  • CAS Number: 5084-31-1
  • MF: C13H8O6
  • MW: 260.19900
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,1-Dimethylurea-d6

1,1-Dimethylurea-d6 is the deuterium labeled 1,1-Dimethylurea[1].

  • CAS Number: 1219802-32-0
  • MF: C3H2D6N2O
  • MW: 94.15
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Arzoxifene

Arzoxifene (LY353381) is an orally active selective estrogen receptor modulator with a fixed ring structure similar to raloxifene. Arzoxifene has minimal side effects with powerful antiestrogenic effects on breast cancer and endometrium, with equally strong favorable estrogenic effects on bone and lipid profile[1].

  • CAS Number: 182133-25-1
  • MF: C28H29NO4S
  • MW: 475.59900
  • Catalog: Metabolic Disease
  • Density: 1.234g/cm3
  • Boiling Point: 656.4ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 350.8ºC

3-Methoxy-2-phenyl-4H-chromen-4-one

3-Methoxyflavone is a flavonoid compound isolated from Artemisia incanescens with antiviral activity[1][2].

  • CAS Number: 7245-02-5
  • MF: C16H12O3
  • MW: 252.26
  • Catalog: Infection
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 408.4±45.0 °C at 760 mmHg
  • Melting Point: 114-115ºC (dec.)(lit.)
  • Flash Point: 192.4±15.1 °C

16:0-18:0-16:0 TG-d5

16:0-18:0-16:0 TG-d5 is deuterium labeled 16:0-18:0-16:0 TG.

  • CAS Number: 944709-25-5
  • MF: C53H97D5O6
  • MW: 840.40
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Methyl 2-[(1,1-dioxo-1-thiolan-3-yl)amino]acetate hydrochloride

Methyl N-(1,1-dioxidotetrahydro-3-thienyl)glycinate hydrochloride is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 1177292-41-9
  • MF: C7H14ClNO4S
  • MW: 243.70800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Bromoundecane-d3

1-Bromoundecane-d3 is the deuterium labeled 1-Bromoundecane[1].

  • CAS Number: 1219805-63-6
  • MF: C11H23Br
  • MW: 235.204
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 259.1±3.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 105.0±10.0 °C

Clodronic Acid

Clodronic acid is an orally active bisphosphonate, which is used for researching osteoporosis and diseases associated with excessive bone resorption. Clodronic acid inhibits bone resorption through induction of osteoclast apoptosis. Clodronic acid is effective in the maintenance or improvement of bone mineral density[1].

  • CAS Number: 10596-23-3
  • MF: CH4Cl2O6P2
  • MW: 244.892
  • Catalog: Others
  • Density: 2.3±0.1 g/cm3
  • Boiling Point: 474.7±55.0 °C at 760 mmHg
  • Melting Point: 249-251°
  • Flash Point: 240.9±31.5 °C

(R)-(-)-1,2-Propanediol

(R)-(-)-1,2-Propanediol is a (R)-enantiomer of 1,2-Propanediol that produced from glucose in Escherichia coli expressing NADH-linked glycerol dehydrogenase genes[1].

  • CAS Number: 4254-14-2
  • MF: C3H8O2
  • MW: 76.094
  • Catalog: Metabolic Disease
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 184.8±8.0 °C at 760 mmHg
  • Melting Point: -57ºC
  • Flash Point: 107.2±0.0 °C

FEN1-IN-3

FEN1-IN-3 (Compound 4) is a human flap endonuclease-1 (hFEN1) inhibitor. FEN1-IN-3 stabilizes hFEN1 with an EC50 of 6.8 μM[1].

  • CAS Number: 2109805-87-8
  • MF: C15H12N2O4
  • MW: 284.27
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-((tert-Butoxycarbonyl)amino)-3-(4-chlorophenyl)propanoic acid

2-((tert-Butoxycarbonyl)amino)-3-(4-chlorophenyl)propanoic acid is a phenylalanine derivative[1].

  • CAS Number: 51301-86-1
  • MF: C14H18ClNO4
  • MW: 299.75000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Mca-Pro-Leu-OH

Mca-Pro-Leu is a tripeptide[1].

  • CAS Number: 140430-55-3
  • MF: C23H28N2O7
  • MW: 444.48
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-FAM-LL-37

5-FAM-LL-37 is afluorescent labeled LL-37, human (HY-P1222).

  • CAS Number: 2243219-81-8
  • MF: C226H350N60O59
  • MW: 4851.56
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

NA-184

NA-184 is a selective calpain-2 inhibitor. NA-184 inhibits TBI-induced cell death with an EC50 of 0.13 mg/kg[1].

  • CAS Number: 2688119-39-1
  • MF: C27H35ClN4O5
  • MW: 531.04
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Senecionine

Senecionine is a pyrrolizidine alkaloid isolated from Senecio vulgaris. Senecionine is toxic to animals and humans.

  • CAS Number: 130-01-8
  • MF: C18H25NO5
  • MW: 335.395
  • Catalog: Metabolic Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 563.7±50.0 °C at 760 mmHg
  • Melting Point: 236ºC(lit.)
  • Flash Point: 294.7±30.1 °C