Verpasep caltespen
Modify Date: 2025-08-27 10:00:46
Verpasep caltespen structure
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Common Name | Verpasep caltespen | ||
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| CAS Number | 295371-00-5 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Verpasep caltespenVerpasep caltespen (HspE7) is a recombinant fusion protein derived from Mycobacterium bovis Calmette-Guérin heat shock protein 65 (Hsp65), the C-terminal end of which is covalently linked to the E7 protein of HPV16. Verpasep caltespen can be used in the study of precancerous and cancerous lesions caused by human papillomavirus (HPV) [1][2]. |
| Name | Verpasep caltespen |
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| Description | Verpasep caltespen (HspE7) is a recombinant fusion protein derived from Mycobacterium bovis Calmette-Guérin heat shock protein 65 (Hsp65), the C-terminal end of which is covalently linked to the E7 protein of HPV16. Verpasep caltespen can be used in the study of precancerous and cancerous lesions caused by human papillomavirus (HPV) [1][2]. |
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| Related Catalog | |
| In Vitro | Verpasep caltespen（HspE7）（50μg/mL，48小时）能在 C57BL/6 小鼠的集合脾细胞中免疫诱导 GM-CSF、IFN-γ 和 IL-5 的分泌，表明 HspE7 具有刺激先天免疫细胞分泌促炎性细胞因子和刺激抗原特异性免疫细胞分泌免疫刺激细胞因子的能力[2]。 |
| In Vivo | Verpasep caltespen（HspE7）（s.c.，20-500 μg，一次或两次，间隔 8 周）在 C57BL/6 小鼠中以剂量依赖的方式诱导细胞毒性 T 淋巴细胞（CTL）活性，在20 μg 时引发微弱的 E7 特异性 CTL 活性，在 250 至 500 μg 的剂量给药时观察到约 60% 的峰值裂解活性[2]。 |
| References |
| No Any Chemical & Physical Properties |