2914922-78-2
2914922-78-2 structure
- Name: Anticancer agent 103
- Chemical Name: Anticancer agent 103
- CAS Number: 2914922-78-2
- Molecular Formula: C18H20BrN3O
- Molecular Weight: 374.27
- Catalog: Research Areas Cancer
- Create Date: 2023-07-04 17:45:22
- Modify Date: 2024-04-03 20:38:15
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Anticancer agent 103 (Compound 2k) is a potent anticancer agent[1].
| Name | Anticancer agent 103 |
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| Description | Anticancer agent 103 (Compound 2k) is a potent anticancer agent[1]. |
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| Related Catalog | |
| In Vitro | Anticancer agent 103 (Compound 2k; 12.5-400 μM; 24 or 48 h) 抑制 HepG2 细胞活力，但不抑制 Colo-205 细胞活力[1]。 Anticancer agent 103 (25 and 50 μM; 24 h) 增加 HepG2 细胞中 FoXO1、TXNIP 和 p27 蛋白水平[1]。 Cell Viability Assay[1] Cell Line: HepG2 and Colo-205 cells Concentration: 12.5, 25, 50, 100, 200 and 400 μM Incubation Time: 24 or 48 h Result: Demonstrated anticancer activity against cancer cell line HepG2 with IC50s of 30.5 μM and 14.8 μM for 24h and 48 h, respectively. The IC50 for Colo-205 was >400 μM. Western Blot Analysis[1] Cell Line: HepG2 cells Concentration: 25 and 50 μM Incubation Time: 24 h Result: Increased the FoXO1, TXNIP and p27 protein levels. |
| References |
| Molecular Formula | C18H20BrN3O |
|---|---|
| Molecular Weight | 374.27 |