Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

7-Acetyl-5-oxo-5H-(1)benzopyra

Y 9000 is an orally active anti-allergic agent [1].

  • CAS Number: 53944-40-4
  • MF: C14H9NO3
  • MW: 239.22600
  • Catalog: Inflammation/Immunology
  • Density: 1.341g/cm3
  • Boiling Point: 446.8ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 224ºC

h-val-pna

L-Valine p-nitroanilide is a biologically active peptide.

  • CAS Number: 52084-13-6
  • MF: C11H15N3O3
  • MW: 237.25500
  • Catalog: Others
  • Density: 1.259g/cm3
  • Boiling Point: 446.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 223.8ºC

Sodium lauryl polyoxyethylene ether sulfate

Sodium lauryl polyoxyethylene ether sulfate is an anionic surfactant, with excellent decontamination, emulsification, dispersion, wetting, solubilizing performance and foaming property.Target:Good solvency, thickening effect, wide compatibility, anti-hard water and high biodegradable ability. Low irritation to skin and eyes. Widely used in liquid detergent such as dishwashing detergent, shampoo, bubble bath liquid, hand washing etc. In washing powder and detergent for heavy dirty, using it to partially replace LABSA, phosphate can be saved or reduced, and general dosage of active matter is reduced. In textile, printing and dyeing industry, petroleum and leather industry, it can be used as lubricant, dyeing agent, cleanser, foaming agent and degreasing agent.

  • CAS Number: 9004-82-4
  • MF: (C2H4O)nC12H26O4S.Na
  • MW: 332.432
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Zinc Sulfate Heptahydrate

Zinc sulfate heptahydrate is a hydrate that is the heptahydrate form of zinc sulfate.

  • CAS Number: 7446-20-0
  • MF: H14O11SZn
  • MW: 287.579
  • Catalog: Others
  • Density: 1.957
  • Boiling Point: 330ºC at 760 mmHg
  • Melting Point: 100 °C
  • Flash Point: N/A

Gamitrinib TPP

Gamitrinib TPP is a GA mitochondrial matrix inhibitor. Gamitrinib TPP is offered as the hexafluorophosphate salt (Cat# HY-102007A).

  • CAS Number: 1131626-46-4
  • MF: C52H65N3O8P
  • MW: 891.059999999999
  • Catalog: HSP
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Foralumab

Foralumab (NI-0401) is a potent, orally active humanized monoclonal antibody targeting the CD3. Foralumab modulates immune responses by human cells in NSG mice that were reconstituted with human hematopoietic stem cells[1].

  • CAS Number: 946415-64-1
  • MF:
  • MW:
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-His-ome

Boc-His-OMe is a histidine derivative[1].

  • CAS Number: 2488-14-4
  • MF: C12H19N3O4
  • MW: 269.29700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Z-Met-OH

Z-Met-OH is a Methionine (HY-13694) derivative[1].

  • CAS Number: 1152-62-1
  • MF: C13H17NO4S
  • MW: 283.343
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 504.7±50.0 °C at 760 mmHg
  • Melting Point: 67-69 °C
  • Flash Point: 259.0±30.1 °C

N-Cbz-L-Serine

Z-Ser-OH is a serine derivative[1].

  • CAS Number: 1145-80-8
  • MF: C11H13NO5
  • MW: 239.225
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 487.5±45.0 °C at 760 mmHg
  • Melting Point: 116-119 °C(lit.)
  • Flash Point: 248.6±28.7 °C

4-bromo(H)benzonitrile

4-Bromobenzonitrile-d4 is the deuterium labeled 4-Bromobenzonitrile[1].

  • CAS Number: 771534-56-6
  • MF: C7BrD4N
  • MW: 186.04200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Dodecyl-N,N-dimethyldodecan-1-aminium-d5 bromide

N-Dodecyl-N,N-dimethyldodecan-1-aminium-d5 (bromide) is the deuterium labeled N-Dodecyl-N,N-dimethyldodecan-1-aminium bromide[1].

  • CAS Number: 1219799-21-9
  • MF: C16H34O
  • MW: 242.441
  • Catalog: Others
  • Density: 0.8±0.1 g/cm3
  • Boiling Point: 310.9±5.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 135.0±0.0 °C

BOC-(S)-3-AMINO-3-(3-PYRIDYL)-PROPIONIC ACID

(S)-3-((tert-Butoxycarbonyl)amino)-3-(pyridin-3-yl)propanoic acid is an alanine derivative[1].

  • CAS Number: 297773-45-6
  • MF: C13H18N2O4
  • MW: 266.29300
  • Catalog: Others
  • Density: 1.198g/cm3
  • Boiling Point: 455ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 229ºC

G0 N-glycan-Asn

G0 N-glycan-Asn is a glycopeptide. G0 N-glycan-Asn can be used for various biochemical studies[1].

  • CAS Number: 68418-91-7
  • MF: C54H90N6O38
  • MW: 1431.31
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(S)-4-Phenyl-L-proline

(4S)-4-Phenyl-L-proline is a proline derivative[1].

  • CAS Number: 96314-26-0
  • MF: C11H13NO2
  • MW: 191.226
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 372.8±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 179.3±27.9 °C

Epivitexolide D

Vitexolide E is a diterpenoid compound isolated from the leaves of the Malaysian species Vitex vestita. Vitexolide E shows cytotoxic activities against the HCT-116 cancer cell line and human fetal lung fibroblast MRC5 cell line[1].

  • CAS Number: 958885-86-4
  • MF: C20H30O3
  • MW: 318.45
  • Catalog: Cancer
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 468.0±20.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 187.5±14.5 °C

CSF1R-IN-13

CSF1R-IN-13 is a potent inhibitor of CSF1R. Colony stimulating factor 1 (CSF-1, also known as macrophage colony stimulating factor, M-CSF) is an important growth factor that controls bone marrow progenitor cells, monocytes, macrophages, and giants. CSF1R-IN-13 has the potential for the research of cancer diseases (extracted from patent WO2019134661A1, compound 32)[1].

  • CAS Number: 2361556-61-6
  • MF: C21H20N4O3
  • MW: 376.41
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

alpha-Lapachone

α-Lapachone shows trypanocidal activity[1].

  • CAS Number: 4707-33-9
  • MF: C15H14O3
  • MW: 242.270
  • Catalog: Infection
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 372.9±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 165.5±27.9 °C

fmoc-D-2-cyanophenylalanine

Fmoc-D-Phe(2-CN)-OH is a phenylalanine derivative[1].

  • CAS Number: 401620-74-4
  • MF: C25H20N2O4
  • MW: 412.437
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 666.0±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 356.6±31.5 °C

sodium,3-[[4-(1,1,1,3,3,3-hexafluoro-2-methylpropan-2-yl)oxycarbonylphenyl]methyl]-2-oxochromen-4-olate

Tecarfarin sodium (ATI-5923 sodium) is a novel orally active non-competitive vitamin K epoxide reductase (VKOR) antagonist, impairs the activation of the vitamin K-dependent clotting factors II, VII, IX and X[1]. Tecarfarin sodium has the antithrombotic activity, attenuates venous and arterial thrombus formation in animal models by reducing the levels of the vitamin K-dependent coagulation factors[2].

  • CAS Number: 1004551-83-0
  • MF: C21H13F6NaO5
  • MW: 482.30500
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Beta-D-Glucopyranosyl nitromethane

Beta-D-Glucopyranosyl nitromethane, as a salt of a strongly basic anion exchanger in the OH cycle, is a glycosyl derivative of nitromethane[1].

  • CAS Number: 81846-60-8
  • MF: C7H13NO7
  • MW: 223.18100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

LIPOPHILIC SEPHADEX

Sephadex LH 20 could be used for the isolation of natural compounds and food, such as red wine and pigments[1].

  • CAS Number: 9041-37-6
  • MF: C9H8N2O3S
  • MW: 224.23642
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Diammonium phosphate

Diammonium phosphate is a neutral and efficient catalyst in 1,8‐Dioxo‐octahydroxanthene derivatives synthesis. Diammonium phosphate can be used as an excipient, such as diuretic, buffer, effervescent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

  • CAS Number: 7783-28-0
  • MF: H9N2O4P
  • MW: 132.06
  • Catalog: Others
  • Density: 1.203 g/mL at 25 °C
  • Boiling Point: 158ºC at 760 mmHg
  • Melting Point: 155 °C (dec.)(lit.)
  • Flash Point: N/A

2-Bromo-1,4-difluorobenzene-d3

2-Bromo-1,4-difluorobenzene-d3 is the deuterium labeled 2-Bromo-1,4-difluorobenzene[1].

  • CAS Number: 1219795-54-6
  • MF: C6H3BrF2
  • MW: 192.989
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 155.4±20.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 65.0±0.0 °C

2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene

2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene, a diterpenoid, has significant effects on DPPH radical scavenging activity with an IC50 value of 20.0 µM. 2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene shows potent antioxidant activity[1].

  • CAS Number: 1608462-12-9
  • MF: C20H28O4
  • MW: 332.43392
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Thiolutin

Thiolutin (Acetopyrrothin) is a disulfide-containing antibiotic and anti-angiogenic compound produced by Streptomyces. Thiolutin inhibits the JAMM metalloproteases Csn5, Associated-molecule-with-the-SH3-Domain-of-STAM (AMSH) and Brcc36[1]. Thiolutin is a potent and selective inhibitor of endothelial cell adhesion accompanied by rapid induction of Heat-shock protein beta-1 (Hsp27) phosphorylation[2].

  • CAS Number: 87-11-6
  • MF: C8H8N2O2S2
  • MW: 228.291
  • Catalog: Stearoyl-CoA Desaturase (SCD)
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 478.6±45.0 °C at 760 mmHg
  • Melting Point: 273-276℃
  • Flash Point: 243.3±28.7 °C

l-4'-tetrahydropyranylglycine

(S)-2-Amino-2-(tetrahydro-2H-pyran-4-yl)ethanoic acid is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 811842-25-8
  • MF: C7H13NO3
  • MW: 159.183
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 316.7±17.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 145.3±20.9 °C

PKC substrate (MBP)

[pGlu4]-Myelin Basic Protein (4-14) is the phosphorylated 4-14 fragment (EKRPSQRSKYL) of myelin basic protein (MBP)[1]. [pGlu4]-Myelin Basic Protein (4-14) surrounds the serine residue in position 8 of the myelin basic protein[2].

  • CAS Number: 136132-68-8
  • MF: C60H100N20O17
  • MW: 1373.56000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Antitumor agent-31

Antitumor agent-31 is a nanosized chelates of anchoring bisazo dye. Antitumor agent-31 can be used for an antioxidant and antitumor agent[1].

  • CAS Number: 2703000-00-2
  • MF: C18H12N8O4S2
  • MW: 468.47
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Isobutylbenzoicacid

4-Isobutylbenzoic acid is an intermediate in the synthesis of compounds[1].

  • CAS Number: 38861-88-0
  • MF: C11H14O2
  • MW: 178.228
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 293.1±19.0 °C at 760 mmHg
  • Melting Point: 144°C
  • Flash Point: 138.8±16.2 °C

WRN inhibitor 5

WRN inhibitor 5 (example 157), a cyclic vinyl sulfone compound, is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor. WRN inhibitor 5 can be used for the research of cancer[1].

  • CAS Number: 2923009-95-2
  • MF: C23H20N2O6S
  • MW: 452.48
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A