Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Galactinol (hydrate)

Galactinol dihydrate is a marker for seed longevity. Galactinol dihydrate can scavenge hydroxyl radicals and protect plant cells from oxidative damage caused by MV treatment, salinity, or chilling[1].

  • CAS Number: 1217474-91-3
  • MF: C12H26O13
  • MW: 378.327
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

6-Chloro-7-hydroxy-4-methylcoumarin

6-Chloro-7-hydroxy-4-methylcoumarin (compound 3) an intermediate of pharmaceutical synthesis[1].

  • CAS Number: 19492-02-5
  • MF: C10H7ClO3
  • MW: 210.61400
  • Catalog: Others
  • Density: 1.447g/cm3
  • Boiling Point: 388.7ºC at 760mmHg
  • Melting Point: 278ºC
  • Flash Point: 188.9ºC

Fmoc-Glu-Oall

Fmoc-Glu-OAll is a glutamic acid derivative[1].

  • CAS Number: 144120-54-7
  • MF: C23H23NO6
  • MW: 409.43200
  • Catalog: Others
  • Density: 1.264g/cm3
  • Boiling Point: 652.3ºC at 760 mmHg
  • Melting Point: 118-122ºC
  • Flash Point: 348.3ºC

Orobanchyl acetate

Orobanchyl acetate, a natural strigolactone, is a germination stimulant for root parasitic plants[1].

  • CAS Number: 1413843-71-6
  • MF: C21H24O7
  • MW: 388.411
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

12β-Acetoxyganoderic Acid θ

12β-Acetoxyganoderic Acid θ is a triterpenoid that can be isolated from G. lucidum[1].

  • CAS Number: 2374206-90-1
  • MF: C32H44O9
  • MW: 572.69
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Delta (Phospho) Sleep Inducing Peptide

Delta (Phospho) Sleep Inducing Peptide (DSIP-P) is a long-lasting sleep-promoting peptide. Delta (Phospho) Sleep Inducing Peptide induces changes in the circadian locomotor behavior in rats[1][2][3].

  • CAS Number: 70754-23-3
  • MF: C35H49N10O18P
  • MW: 928.794
  • Catalog: Neurological Disease
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Goniopypyrone

Goniopypyrone (compound 6) is a styryl-lactone that can be found in Goniothalamus tapis Miq[1].

  • CAS Number: 129578-07-0
  • MF: C13H14O5
  • MW: 250.25
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 547.4±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 216.8±23.6 °C

4-HYDROXY-4-METHYLCYCLOHEXANONE

4-Hydroxy-4-methylcyclohexanone is a useful synthetic reagent extracted from patent JP2009022162A. 4-Hydroxy-4-methylcyclohexanone can be used to synthesize trans-4-amino-1-methylcyclohexanol which is intermediate of pharmaceutical synthesis[1].

  • CAS Number: 17429-02-6
  • MF: C7H12O2
  • MW: 128.16900
  • Catalog: Others
  • Density: 1.082g/cm3
  • Boiling Point: 222.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 89.3ºC

CMP-Sialic acid sodium salt

CMP-Sialic acid sodium salt (CMP-Neu5Ac sodium salt) is an allosteric inhibitor of UDP-GlcNAc 2-epimerase, the enzyme that initiates sialic acid synthesis. CMP-Sialic acid sodium salt provides a substrate for Golgi sialyltransferases[1].

  • CAS Number: 1007117-62-5
  • MF: C20H30N4NaO16P
  • MW: 636.433
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Hydroxy(2H4)benzonitrile

4-Cyanophenol-d4 is the deuterium labeled 4-Cyanophenol[1].

  • CAS Number: 1025089-21-7
  • MF: C7HD4NO
  • MW: 123.145
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 281.2±23.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 123.9±22.6 °C

2-Isobutyl-3-methoxypyrazine

2-Isobutyl-3-methoxypyrazine is an aroma constituent in grapes andwines, green pepper and asparagus[1].

  • CAS Number: 24683-00-9
  • MF: C9H14N2O
  • MW: 166.220
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 210.8±35.0 °C at 760 mmHg
  • Melting Point: 107ºC
  • Flash Point: 80.0±0.0 °C

4-Chloro-D-Phe-OMe·HCl

H-D-Phe(4-Cl)OMe.HCl is a phenylalanine derivative[1].

  • CAS Number: 33965-47-8
  • MF: C10H13Cl2NO2
  • MW: 250.122
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 330ºC at 760 mmHg
  • Melting Point: 195-197°C
  • Flash Point: 153.4ºC

Butachlore

Butachlor is an herbicide of the acetanilide class. Butachlor is used as a selective pre-emergent herbicide[1].

  • CAS Number: 23184-66-9
  • MF: C17H26ClNO2
  • MW: 311.847
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 442.0±45.0 °C at 760 mmHg
  • Melting Point: <-5ºC
  • Flash Point: 221.1±28.7 °C

1-(2-nitro-4,5-dimethoxyphenyl)-N,N,N',N'-tetrakis((oxycarbonyl)methyl)-1,2-ethanediamine

DM-Nitrophen is a Ca2+ cage. DM-Nitrophen releases Ca2+ when cleaved upon illumination with near-ultraviolet light[1].

  • CAS Number: 117367-86-9
  • MF: C18H23N3O12
  • MW: 473.38800
  • Catalog: Others
  • Density: 1.537g/cm3
  • Boiling Point: 806.7ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 441.7ºC

Theaflavin-3-gallate

Theaflavin-3-gallate, a black tea theaflavin monomer, is regarded as the biologically important active component of black tea and provides health benefits. Theaflavin-3-gallate acts as prooxidants and induces oxidative stress in the carcinoma cells. Theaflavin-3-gallate reacts directly with reduced glutathione (GSH) in a time- and concentration-dependent manner[1].

  • CAS Number: 30462-34-1
  • MF: C36H28O16
  • MW: 716.598
  • Catalog: Cancer
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 1202.8±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 382.0±27.8 °C

EPI-589

EPI-589, a quinone derivative, is a safe and well tolerated oxidoreductase enzyme inhibitor. EPI-589 has the potential for the treatment of amyotrophic lateral sclerosis (ALS)[1].

  • CAS Number: 1147883-03-1
  • MF: C14H19NO4
  • MW: 265.30
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,7-Dimethoxy-6-(1-acetoxyethyl)juglone

2,7-Dimethoxy-6-(1-acetoxyethyl)juglone is a naphthoquinone derivative found in the fungus Kirschsteiniothelia species[1].

  • CAS Number: 68594-15-0
  • MF: C16H16O7
  • MW: 320.29400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(3β)-(25,26,26,27,27,27-2H6)Cholest-5-ene-3,26-diol

27-Hydroxy cholesterol-d6 is deuterium labeled 27-Hydroxy cholesterol.

  • CAS Number: 1246302-95-3
  • MF: C27H40D6O2
  • MW: 408.690
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 517.1±23.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 215.6±17.2 °C

Rubiadin

Rubiadin is a dihydroxy anthraquinone isolated from Rubia cordifolia. Rubiadin has a potent antixidant activity[1].

  • CAS Number: 117-02-2
  • MF: C15H10O4
  • MW: 254.238
  • Catalog: Inflammation/Immunology
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 527.1±30.0 °C at 760 mmHg
  • Melting Point: 290ºC
  • Flash Point: 286.6±21.1 °C

Dymanthine

Dymanthine is an anthelminthic. Dymanthine has the potential for the research of multiple intestinal helmintic infestations[1][2].

  • CAS Number: 124-28-7
  • MF: C20H43N
  • MW: 297.562
  • Catalog: Others
  • Density: 0.8±0.1 g/cm3
  • Boiling Point: 348.5±5.0 °C at 760 mmHg
  • Melting Point: 23 °C
  • Flash Point: 153.8±5.2 °C

Fmoc-N-Me-Thr-OH

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N-methyl-L-threonine is a threonine derivative[1].

  • CAS Number: 252049-06-2
  • MF: C20H21NO5
  • MW: 355.384
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 566.4±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 296.4±30.1 °C

Delta-hemolysin

Delta-hemolysin is a biological active peptide. (Delta -Lysin is a 26-residue hemolytic peptide secreted by Staphylococcus aureus, it is a delta-toxin. It is produced by most of the strains of S. aureus. This toxin is lytic to many kinds of cells by solubilization of their membranes.)

  • CAS Number: 74838-20-3
  • MF: C137H225N33O40S
  • MW: 3006.51
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-[[4-[(4-aminophenyl)sulphonyl]phenyl]amino]-4-oxobutyric acid

4-((4-((4-Aminophenyl)sulfonyl)phenyl)amino)-4-oxobutanoic acid is a sulfonamide antiinfective agent[1].

  • CAS Number: 5934-14-5
  • MF: C16H16N2O5S
  • MW: 348.37400
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 157°
  • Flash Point: N/A

l-menthone

(-)-Menthone is a monoterpene component of the essential oil of maturing peppermint. (+)-Neomenthyl-β-d-glucoside is a metabolite of (-)-Menthone[1].

  • CAS Number: 14073-97-3
  • MF: C10H18O
  • MW: 154.24900
  • Catalog: Others
  • Density: 0.89
  • Boiling Point: 207-210ºC
  • Melting Point: -6ºC
  • Flash Point: 72ºC

Praeruptorin B

Praeruptorin B is an inhibitor of sterol regulatory element-binding proteins (SREBPs).

  • CAS Number: 73069-28-0
  • MF: C24H26O7
  • MW: 426.459
  • Catalog: Metabolic Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 524.8±50.0 °C at 760 mmHg
  • Melting Point: 175-176ºC
  • Flash Point: 225.5±30.2 °C

N-Acetyl-DL-Alanine

Ac-DL-Ala-OH is an alanine derivative[1].

  • CAS Number: 1115-69-1
  • MF: C5H9NO3
  • MW: 131.130
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 369.7±25.0 °C at 760 mmHg
  • Melting Point: 137-139ºC
  • Flash Point: 177.4±23.2 °C

BiCAPPA

BiCAPPA is the first bivalent antiprion ligand. BiCAPPA can decrease infectious conformational form of prion protein (PrPSc) from scrapie-infected cells, with an EC50 of 0.32 μM[1][2].

  • CAS Number: 119662-55-4
  • MF: C38H40Cl2N6O2
  • MW: 683.66900
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Arg-OEt·2HCl

L-Arginine ethyl ester dihydrochloride is an arginine derivative[1].

  • CAS Number: 36589-29-4
  • MF: C8H20Cl2N4O2
  • MW: 275.176
  • Catalog: Others
  • Density: 1.26g/cm3
  • Boiling Point: 343.3ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 161.4ºC

Benzenamine, N-phenyl-,hydrochloride (1:1)

Diphenylamine hydrochloride, an organic compound isolated from coriander, is used mainly for its antioxidant properties. Diphenylamine is used as an industrial antioxidant, dye mordant and is also applied in agriculture as a fungicide and antihelmintic[1].

  • CAS Number: 537-67-7
  • MF: C12H12ClN
  • MW: 205.68300
  • Catalog: Others
  • Density: 1.088g/cm3
  • Boiling Point: 302ºC at 760 mmHg
  • Melting Point: 180 °C
  • Flash Point: 152.8ºC

Verilopam

Verilopam is a potent analgesic.

  • CAS Number: 68318-20-7
  • MF: C20H26N2O2
  • MW: 326.43300
  • Catalog: Neurological Disease
  • Density: 1.111g/cm3
  • Boiling Point: 494.8ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 253.1ºC