4-[[4-[(4-aminophenyl)sulphonyl]phenyl]amino]-4-oxobutyric acid

Modify Date: 2025-08-23 19:06:20

4-[[4-[(4-aminophenyl)sulphonyl]phenyl]amino]-4-oxobutyric acid Structure
4-[[4-[(4-aminophenyl)sulphonyl]phenyl]amino]-4-oxobutyric acid structure
Common Name 4-[[4-[(4-aminophenyl)sulphonyl]phenyl]amino]-4-oxobutyric acid
CAS Number 5934-14-5 Molecular Weight 348.37400
Density N/A Boiling Point N/A
Molecular Formula C16H16N2O5S Melting Point 157°
MSDS N/A Flash Point N/A

 Use of 4-[[4-[(4-aminophenyl)sulphonyl]phenyl]amino]-4-oxobutyric acid


4-((4-((4-Aminophenyl)sulfonyl)phenyl)amino)-4-oxobutanoic acid is a sulfonamide antiinfective agent[1].

 Names

Name 4-[4-(4-aminophenyl)sulfonylanilino]-4-oxobutanoic acid
Synonym More Synonyms

  Biological Activity

Description 4-((4-((4-Aminophenyl)sulfonyl)phenyl)amino)-4-oxobutanoic acid is a sulfonamide antiinfective agent[1].
Related Catalog
References

[1]. Abdel-Majid Khatib, et al. Utilisation d'inhibiteurs tmprss2 permettant le traitement d'infections virales pulmonaires. WO2021228762A1.

 Chemical & Physical Properties

Melting Point 157°
Molecular Formula C16H16N2O5S
Molecular Weight 348.37400
Exact Mass 348.07800
PSA 134.94000
LogP 3.63990

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WM3406500
CHEMICAL NAME :
Succinalic acid, 4'-sulfanilyl-
CAS REGISTRY NUMBER :
5934-14-5
BEILSTEIN REFERENCE NO. :
3458725
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H16-N2-O5-S
MOLECULAR WEIGHT :
348.40
WISWESSER LINE NOTATION :
ZR DSWR DMV2VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 6,251,1951

 Synthetic Route

~%

4-[[4-[(4-aminophenyl)sulphonyl]phenyl]amino]-4-oxobutyric acid Structure

4-[[4-[(4-amino...

CAS#:5934-14-5

Literature: Bauer Journal of the American Chemical Society, 1948 , vol. 70, p. 2254

~%

4-[[4-[(4-aminophenyl)sulphonyl]phenyl]amino]-4-oxobutyric acid Structure

4-[[4-[(4-amino...

CAS#:5934-14-5

Literature: Farbenfabr. Bayer Patent: DE895600 , 1941 ;

~%

4-[[4-[(4-aminophenyl)sulphonyl]phenyl]amino]-4-oxobutyric acid Structure

4-[[4-[(4-amino...

CAS#:5934-14-5

Literature: Farbenfabr. Bayer Patent: DE895600 , 1941 ;

~%

4-[[4-[(4-aminophenyl)sulphonyl]phenyl]amino]-4-oxobutyric acid Structure

4-[[4-[(4-amino...

CAS#:5934-14-5

Literature: E.Lilly and Co. Patent: US2268754 , 1940 ;

~%

4-[[4-[(4-aminophenyl)sulphonyl]phenyl]amino]-4-oxobutyric acid Structure

4-[[4-[(4-amino...

CAS#:5934-14-5

Literature: Farbenfabr. Bayer Patent: DE895600 , 1941 ;

 Synonyms

Succisulfone
Succisulfona
Succinylsulfone
Succisulfon
4-({4-[(4-aminophenyl)sulfonyl]phenyl}amino)-4-oxobutyric acid
N-(4-Sulfanilyl-phenyl)-succinamidsaeure
Succisulfonum
Exosulfonyl
F 1500
EINECS 227-684-5
Succinalic acid,4'-sulfanilyl
N-(4-sulfanilyl-phenyl)-succinamic acid
4'-Sulfanilylsuccinalic acid
N-[4-(4-Amino-phenylsulfon)-phenyl]-succinamidsaeure
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