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4-[[4-[(4-aminophenyl)sulphonyl]phenyl]amino]-4-oxobutyric acid

Names

[ CAS No. ]:
5934-14-5

[ Name ]:
4-[[4-[(4-aminophenyl)sulphonyl]phenyl]amino]-4-oxobutyric acid

[Synonym ]:
Succisulfone
Succisulfona
Succinylsulfone
Succisulfon
4-({4-[(4-aminophenyl)sulfonyl]phenyl}amino)-4-oxobutyric acid
N-(4-Sulfanilyl-phenyl)-succinamidsaeure
Succisulfonum
Exosulfonyl
F 1500
EINECS 227-684-5
Succinalic acid,4'-sulfanilyl
N-(4-sulfanilyl-phenyl)-succinamic acid
4'-Sulfanilylsuccinalic acid
N-[4-(4-Amino-phenylsulfon)-phenyl]-succinamidsaeure

Biological Activity

[Description]:

4-((4-((4-Aminophenyl)sulfonyl)phenyl)amino)-4-oxobutanoic acid is a sulfonamide antiinfective agent[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Others >> Others

[References]

[1]. Abdel-Majid Khatib, et al. Utilisation d'inhibiteurs tmprss2 permettant le traitement d'infections virales pulmonaires. WO2021228762A1.

Chemical & Physical Properties

[ Melting Point ]:
157°

[ Molecular Formula ]:
C16H16N2O5S

[ Molecular Weight ]:
348.37400

[ Exact Mass ]:
348.07800

[ PSA ]:
134.94000

[ LogP ]:
3.63990

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WM3406500
CHEMICAL NAME :
Succinalic acid, 4'-sulfanilyl-
CAS REGISTRY NUMBER :
5934-14-5
BEILSTEIN REFERENCE NO. :
3458725
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H16-N2-O5-S
MOLECULAR WEIGHT :
348.40
WISWESSER LINE NOTATION :
ZR DSWR DMV2VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 6,251,1951

Synthetic Route

Precursor & DownStream


Related Compounds

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