Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

5-Tricosyl-1,3-benzenediol

5-n-Tricosylresorcinolthe is the first cyst lipid. 5-n-Tricosylresorcinolthe has metahydroxyl group which allows it to self-associate forming a staggered-chain conformation in which the polar head groups have heaxagonal symmetry[1].

  • CAS Number: 70110-60-0
  • MF: C29H52O2
  • MW: 432.722
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 550.0±20.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 220.3±16.4 °C

(4,5,6,7-2H4)-1H-Benzotriazole

1H-Benzotriazole-4,5,6,7-d4 is the deuterium labeled 1H-Benzo[d][1,2,3]triazole[1].

  • CAS Number: 1185072-03-0
  • MF: C6HD4N3
  • MW: 123.149
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 359.2±11.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 185.7±12.2 °C

Disialo-Asn

Disialo-Asn is a N-Glycan and sialate glycopeptide. Disialo-Asn can be used for modify nucleic acids[1].

  • CAS Number: 68141-38-8
  • MF: C88H144N8O64
  • MW: 2338.11
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 889.4±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 491.7±34.3 °C

Alpha-L-Rhamnopyranose

α-L-Rhamnose is a terminal residue of steviol glycosides Dulcoside A and Dulcoside B. α-L-Rhamnose recognizing lectin site of human dermal fibroblasts functions as a signal transducer: modulation of Ca2+ fluxes and gene expression[1][2].

  • CAS Number: 6014-42-2
  • MF: C6H14O6
  • MW: 182.17200
  • Catalog: Others
  • Density: 1.556±0.06 g/cm3(Predicted)
  • Boiling Point: 323.9±42.0 °C(Predicted)
  • Melting Point: 91-93ºC
  • Flash Point: N/A

H-DL-Glu(OMe)-OH

H-DL-Glu(Ome)-OH is a glutamic acid derivative[1].

  • CAS Number: 14487-45-7
  • MF: C6H11NO4
  • MW: 161.15600
  • Catalog: Others
  • Density: 1.242g/cm3
  • Boiling Point: 316.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 145ºC

Xenin 25 acetate salt

Xenin is a 25-amino acid peptide initially isolated from human gastric mucosa. Xenin is a gut hormone that can reduce food intake.

  • CAS Number: 144092-28-4
  • MF: C139H224N38O32S
  • MW: 2971.57000
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Lenzilumab

Lenzilumab (KB 003) is a humanized monoclonal antibody targeting CSF2/GM-CSF for COVID-19, chronic myelomonocytic leukemia (CMML) and juvenile myelomonocytic leukemia (JMML) studies[1][2].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Victoxinine

Victoxinine is a metabolite of Bipolaris sp. Victoxinine has minor phytotoxic[1].

  • CAS Number: 39965-06-5
  • MF: C17H29NO
  • MW: 263.41800
  • Catalog: Others
  • Density: 1.03g/cm3
  • Boiling Point: 361.9ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 151.7ºC

LEI110(LEI-110

LEI110 (LEI-110) is a potent Phospholipase A2 group XVI (PLA2G16) inhibitor with Ki of 20 nM, also has activity on HRASLS2, RARRES3 and iNAT (pIC50=6.8-7.6); reduces cellular arachidonic acid levels and oleic acid-induced lipolysis in human HepG2 cells; LEI110 is a selective pan-inhibitor of the HRASLS-family of thiol hydrolases (i.e. PLA2G16, HRASLS2, RARRES3 and iNAT).

  • CAS Number: 2313525-90-3
  • MF: C25H23F3N2O3
  • MW: 456.465
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Oleoyl coenzyme A lithium salt

Oleoyl coenzyme A (Oleoyl-CoA) lithium is a thioester of oleic acid and coenzyme A. Oleoyl coenzyme A lithium has a role as an Escherichia coli metabolite and a mouse metabolite[1][2].

  • CAS Number: 188824-37-5
  • MF: C39H64Li4N7O17P3S
  • MW: 1055.71000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(Lys(Ac)5.8.12.16)-Histone H4 (1-25)-Gly-Ser-Gly-Ser-Lys(biotinyl) trifluoroacetate salt

(Lys(Ac)5,8,12,16)-Histone H4 (1-25)-Gly-Ser-Gly-Ser-Lys(biotinyl) is a biologically active peptide.

  • CAS Number: 2022956-65-4
  • MF: C141H243N53O43S
  • MW: 3400.88
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

12-Hydroxyisobakuchiol

12-Hydroxyisobakuchiol, meroterpene derivative, is a natural product. 12-Hydroxyisobakuchiol can be isolated from the leaves of Psoralea glandulosa[1].

  • CAS Number: 178765-55-4
  • MF: C18H24O2
  • MW: 272.38200
  • Catalog: Others
  • Density: 1.026±0.06 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Secologansaeure

Secologanate is a natural secoiridoid glucoside found in Lonicerae Japonicae Caulis[1].

  • CAS Number: 22864-93-3
  • MF: C16H22O10
  • MW: 374.34000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ATN-224

ATN-224 is an oral Cu2+/Zn2+-superoxide dismutase 1 (SOD1) inhibitor. ATN-224 inhibits SOD1 activity in endothelial cells, an effect that is dose dependent with an IC50 of 17.5±3.7 nM.

  • CAS Number: 649749-10-0
  • MF: C10H28MoN2O2S4
  • MW: 432.56
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Triperiden

Triperiden is an inhibitor of influenza virus multiplication. Triperiden targets the haemagglutinin of fowl plague virus (FPV) for antiviral activity and acts by inhibiting the conformational change in the haemagglutinin at acid pH. Triperiden is also anticholinergic anti-parkinsonism drug[1].

  • CAS Number: 14617-17-5
  • MF: C21H30ClNO
  • MW: 347.92200
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: 463ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 228.9ºC

4-Fluorobenzonitrile-d2

4-Fluorobenzonitrile-d2 is the deuterium labeled 4-Fluorobenzonitrile[1].

  • CAS Number: 83741-75-7
  • MF: C5H8D2O2
  • MW: 104.14400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

MELPERONE

Melperone, a butyrophenone, is an antipsychotic drug used for sleep induction which is frequently prescribed in psychiatric setting[1]. Melperone has been used for a variety of indications, including the treatment of schizophrenia, but also for agitation in the elderly[2].

  • CAS Number: 3575-80-2
  • MF: C16H22FNO
  • MW: 263.35000
  • Catalog: Neurological Disease
  • Density: 1.046g/cm3
  • Boiling Point: 376.1ºC at 760mmHg
  • Melting Point: 78-82°C
  • Flash Point: 181.3ºC

(2H8)Dibenzo[b,d]thiophene

Dibenzothiophene-d8 is the deuterium labeled Dibenzothiophene[1].

  • CAS Number: 33262-29-2
  • MF: C12D8S
  • MW: 192.306
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 332.5±11.0 °C at 760 mmHg
  • Melting Point: 97-100ºC(lit.)
  • Flash Point: 114.8±5.5 °C

Dodecyltrimethylammonium-d25 bromide

Dodecyltrimethylammonium-d25 (bromide) is the deuterium labeled Dodecyltrimethylammonium (bromide)[1]. Dodecyltrimethylammonium bromide (DTAB) is a surfactant. Dodecyltrimethylammonium bromide interacts with DNA and changes the mechanical properties of DNA on binding and the specific binding parameters of the interaction[2].

  • CAS Number: 2309360-05-0
  • MF: C15H9D25BrN
  • MW: 333.50
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

MMP-2/MMP-9 Fluorogenic Substrate I

DNP-PLGMWSR is a? fluorogenic substrate for MMP-2 and MMP-9[1].

  • CAS Number: 135662-07-6
  • MF: C44H61N13O13S
  • MW: 1012.10000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Trifluoroacetyl Tripeptide-2

Trifluoroacetyl tripeptide-2 is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient[1].

  • CAS Number: 64577-63-5
  • MF: C21H28F3N3O6
  • MW: 475.459
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 755.4±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 410.7±32.9 °C

11-Azidoundecanoic acid

11-Azidoundecanoic acid is a click chemistry reagent containing an azide group. 11-Azidoundecanoic acid acts as a hydrophobic bioconjugation linker that can be further modified at the azido-position using Staudinger ligation or Click-chemistry. 11-Azidoundecanoic acid is substrate of lipoic acid ligase (LpIA) for labeling[1][2].

  • CAS Number: 118162-45-1
  • MF: C11H21N3O2
  • MW: 227.30300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-(2H4)Pyridin(2H)ol

Pyridin-4-ol-d5 is the deuterium labeled Pyridin-4-ol[1].

  • CAS Number: 45503-33-1
  • MF: C5D5NO
  • MW: 100.130
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 380.6±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 182.3±20.4 °C

Trypanothione

Trypanothione is a bis-glutathionyl derivative, found in trypanosomatids. Trypanothione shows the protection against oxidative stress[1][2][3].

  • CAS Number: 96304-42-6
  • MF: C27H47N9O10S2
  • MW: 721.84600
  • Catalog: Others
  • Density: 1.41±0.1 g/cm3 (20 °C, 760 mmHg)
  • Boiling Point: 1284.7±65.0 °C (760 mmHg)
  • Melting Point: N/A
  • Flash Point: N/A

3,3',4,4'-Biphenyltetramine tetrahydrochloride

3,3'-Diaminobenzidine(DAB) is an organic compound that is both chemically and thermodynamically stable; DAB has been used in immunohistochemical staining of nucleic acids and proteins.

  • CAS Number: 7411-49-6
  • MF: C12H18Cl4N4
  • MW: 360.110
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: 481.7ºC at 760 mmHg
  • Melting Point: 300°C
  • Flash Point: 282.7ºC

2H-1-Benzopyran-4-aceticacid, 7-hydroxy-2-oxo-

7-Hydroxycoumarin-4-acetic acid, a pH-indicator dye, is covalently bound to bovine serum albumin (BSA) at the positions of reactive amino groups (λmax=326 nm)[1].

  • CAS Number: 6950-82-9
  • MF: C11H8O5
  • MW: 220.17800
  • Catalog: Others
  • Density: 1.511 g/cm3
  • Boiling Point: 523.5ºC at 760 mmHg
  • Melting Point: 212 °C (dec.)(lit.)
  • Flash Point: 214.5ºC

Prepro-Atrial Natriuretic Factor (26-55) (human)

Prepro-Atrial Natriuretic Factor (26-55) (human) is a polypeptide that increases renal cortical and medullary cyclic GMP levels. Prepro-Atrial Natriuretic Factor (26-55) (human) increases renal guanylate cyclase activity[1].

  • CAS Number: 112160-82-4
  • MF: C152H236N38O51S3
  • MW: 3507.92
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5'-Phosphoguanylyl-(3',5')-guanosine

5'-Phosphoguanylyl-(3',5')-guanosine (pGpG) is an intermediate molecule produced by the pathway for enzymatic cyclic diguanylate (c-di-GMP) degradation. 5'-Phosphoguanylyl-(3',5')-guanosine can be used to detect the metabolism of nucleic acids[1][2].

  • CAS Number: 33008-99-0
  • MF: C20H26N10O15P2
  • MW: 708.42600
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-DL-Met-OH

(tert-Butoxycarbonyl)methionine is a Methionine (HY-13694) derivative[1].

  • CAS Number: 93000-03-4
  • MF: C10H19NO4S
  • MW: 249.327
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 415.5±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 205.1±27.3 °C

N-Pyrazinylcarbonylphenylalanine-d8

N-Pyrazinylcarbonylphenylalanine-d8 is the deuterium labeled Deruxtecan. Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and amaleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.

  • CAS Number: 1331912-47-0
  • MF: C14H5D8N3O3
  • MW: 279.32
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A