136040-43-2

136040-43-2 structure

Name: Kadsulactone acid
Chemical Name: schisanlactone E
CAS Number: 136040-43-2
Molecular Formula: C₃₀H₄₄O₄
Molecular Weight: 468.67
Catalog: Research Areas Cancer
Create Date: 2018-09-14 18:18:59
Modify Date: 2025-08-25 18:08:45
Schisanlactone E is a triterpenoids that can be isolated from Kadsura heteroclita. Schisanlactone E exhibits moderate cytotoxic activity against Bel-7402, BGC-823, MCF-7 and HL-60 cell line with IC50s of 68.33, 100, >100, 73.37 μM,respectively[1].

Name	schisanlactone E
Synonyms	3-{6-Isopropenyl-3a,9a-dimethyl-1-[1-(5-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)ethyl]decahydro-1H-cyclopenta[a]cyclopropa[e]naphthalen-6a(7H)-yl}propanoic acid 1H-Cyclopenta[a]cyclopropa[e]naphthalene-6a(7H)-propanoic acid, 1-[(1S)-1-[(2R)-3,6-dihydro-5-methyl-6-oxo-2H-pyran-2-yl]ethyl]decahydro-3a,9a-dimethyl-6-(1-methylethenyl)-, (1R,3aS,3bS,6S,6aR,7aS,9aR)- 3-[(1R,3aS,3bS,6S,6aR,7aS,9aR)-3a,9a-Dimethyl-1-{(1S)-1-[(2R)-5-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]ethyl}-6-(prop-1-en-2-yl)decahydro-1H-cyclopenta[a]cyclopropa[e]naphthalen-6a(7H)-yl]propanoic acid 1H-Cyclopenta[a]cyclopropa[e]naphthalene-6a(7H)-propanoic acid, 1-[1-(3,6-dihydro-5-methyl-6-oxo-2H-pyran-2-yl)ethyl]decahydro-3a,9a-dimethyl-6-(1-methylethenyl)- 3-[(1R,3aS,3bS,6S,6aR,7aS,9aR)-6-Isopropenyl-3a,9a-dimethyl-1-{(1S)-1-[(2R)-5-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]ethyl}decahydro-1H-cyclopenta[a]cyclopropa[e]naphthalen-6a(7H)-yl]propanoic acid 1H-cyclopenta[a]cyclopropa[e]naphthalene-6a(7H)-propanoic acid, 1-[1-[(2R)-3,6-dihydro-5-methyl-6-oxo-2H-pyran-2-yl]ethyl]decahydro-3a,9a-dimethyl-6-(1-methylethenyl)-, (1R,3aS,3bS,6S,6aR,7aS,9aR)-

Description	Schisanlactone E is a triterpenoids that can be isolated from Kadsura heteroclita. Schisanlactone E exhibits moderate cytotoxic activity against Bel-7402, BGC-823, MCF-7 and HL-60 cell line with IC50s of 68.33, 100, >100, 73.37 μM,respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Wang W, et al. New triterpenoids from Kadsura heteroclita and their cytotoxic activity. Planta Med. 2006 Apr;72(5):450-7.