Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

L,L-Dityrosine

L,L-Dityrosine is a constituent of acid hydrolysates of a number of biological materials, including the insect cuticular resilin[1].

  • CAS Number: 63442-81-9
  • MF: C18H20N2O6
  • MW: 360.361
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 622.9±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 330.5±31.5 °C

Hexasodium phytate

Hexasodium phytate (Phytic acid hexasodium) is a phosphorus storage compound of seeds and cereal grains. Hexasodium phytate has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Hexasodium phytate inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects.

  • CAS Number: 34367-89-0
  • MF: C6H12Na6O24P6
  • MW: 791.93
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4′-Bromoflavone

4′-Bromoflavone, a cancer chemopreventive agent, is a potent phase II detoxification enzymes inducer[1].

  • CAS Number: 20525-20-6
  • MF: C15H9BrO2
  • MW: 301.13
  • Catalog: Cancer
  • Density: 1.54g/cm3
  • Boiling Point: 406.6ºC at 760 mmHg
  • Melting Point: 174-176ºC
  • Flash Point: 199.7ºC

N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium

N7-Methyl-guanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium is a dinucleotide cap analog that can be used for in vitro RNA transcription[1].

  • CAS Number: 75252-10-7
  • MF: C21H35N12O17P3
  • MW: 820.49
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2: PN: US20040072744 SEQID: 2 claimed protein

2: PN: US20040072744 SEQID: 2 claimed protein is a synthetic peptide, used for the research of Down's syndrome and schizophrenia.

  • CAS Number: 389572-87-6
  • MF: C43H67N13O17S
  • MW: 1070.13
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sulfo-Cy5-tetrazine

Cy5 Tetrazine is a water-soluble, pH-insensitive from pH 4 to pH 10, far-red-fluorescent probe with excitation ideally suited for the 633 nm or 647 nm laser lines. Its absorption and emission spactra are almost identical to those of Alexa Fluor 647, CF 647 Dye, or any other Cyanine5 based fluorescent dyes.

  • CAS Number: 1801695-57-7
  • MF: C43H49N7O10S3
  • MW: 920.09
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

tert-Butyl D-leucinate hydrochloride (1:1)

tert-Butyl D-leucinate hydrochloride is a leucine derivative[1].

  • CAS Number: 13081-32-8
  • MF: C10H22ClNO2
  • MW: 223.740
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Diethyl aminoethyl hexanoate citrate

Diethyl aminoethyl hexanoate citrate is a compound that is widely used as a plant growth regulator.

  • CAS Number: 220439-24-7
  • MF: C18H33NO9
  • MW: 407.45600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Methylcaprylic acid

4-Methyloctanoic acid is a natural compound mainly responsible for the characteristic goaty sheepy flavour of sheep and goat milk[1].

  • CAS Number: 54947-74-9
  • MF: C9H18O2
  • MW: 158.238
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 253.4±8.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 129.7±6.9 °C

Glucagon (19-29) (human, rat, porcine) trifluoroacetate salt

Glucagon (19-29), human is a potent and efficient inhibitor of insulin secretion.

  • CAS Number: 64790-15-4
  • MF: C61H89N15O18S
  • MW: 1352.51000
  • Catalog: Peptides
  • Density: 1.339 g/cm3
  • Boiling Point: 1828.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 1059.6ºC

Dornase alfa

Dornase alfa (rhDNase) is a recombinant human deoxyribonuclease I (rhDNase), an enzyme which selectively cleaves DNA. Dornase alfa hydrolyzes the DNA present in sputum/mucus and reduces viscosity in the lungs, promoting improved clearance of secretions. Dornase alfa plays an important role in cystic fibrosis[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,3-Dioleoyl-2-palmitoylglycerol

1,3-Dioleoyl-2-palmitoylglycerol is an important triacylglycerol in infant formulas[1].

  • CAS Number: 1716-07-0
  • MF: C55H102O6
  • MW: 859.39500
  • Catalog: Others
  • Density: 0.919g/cm3
  • Boiling Point: 802.2ºC at 760 mmHg
  • Melting Point: 19°C (lit.)
  • Flash Point: 298.4ºC

BODIPY TR methyl ester

BODIPY TR methyl ester is a lipophilic GFP Counterstain. BODIPY TR methyl ester dye readily permeates cell membranes and localizes in endomembranous organelles but not localize strongly in plasma membranes. BODIPY TR methyl ester is an excellent red fluorescent vital dye (Ex=568 nm, Em=625 nm), can be used to reveal the location and shapes of cell nuclei, the shapes of cells within embryonic tissues, as well as the bound aries of organ-forming tissues within the whole embryo[1].

  • CAS Number: 150152-63-9
  • MF: C22H17BF2N2O3S
  • MW: 438.255
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Luvangetin

Luvangetin is a coumarin that can be isolated from Zanthoxylum avicennae[1].

  • CAS Number: 483-92-1
  • MF: C15H14O4
  • MW: 258.27
  • Catalog: Others
  • Density: 1.225g/cm3
  • Boiling Point: 431.8ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 193.9ºC

Suxibuzone

Suxibuzone is a drug used for joint and muscular pain, is a prodrug of the non steroidal anti inflammatory drug Phenylbutazone.

  • CAS Number: 27470-51-5
  • MF: C24H26N2O6
  • MW: 438.47300
  • Catalog: Inflammation/Immunology
  • Density: 1.265g/cm3
  • Boiling Point: 590.1ºC at 760 mmHg
  • Melting Point: 126-127°
  • Flash Point: 310.7ºC

Thromboxane B2-d4

Thromboxane B2-D4 is the deuterium labeled Thromboxane B2. Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation[1][2].

  • CAS Number: 1346112-79-5
  • MF: C20H30D4O6
  • MW: 374.50500
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Leu-Ser-Phe-OH

H-Leu-Ser-Phe-OH is a biologically active peptide.

  • CAS Number: 40290-77-5
  • MF: C18H27N3O5
  • MW: 365.424
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 691.2±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 371.8±31.5 °C

S186

S186 is a kind of sodium salts of calcium-acetylpropylamine phosphonate(APA); a new strontium-specific chelating agent.IC50 value:Target: In a case test for 4 person who took 90Sr in due to an internal contaminated accident, the APAP was adminstrated intramuscularly once a day for 3 days, the increase excretion of 90Sr was obvious and no side effects was observed among them. Recently, S186 has also been approved by Shanghai Municipal Health Bureau for emergency medical use in China.

  • CAS Number: 97759-16-5
  • MF: C5H13CaNNaO7P2
  • MW: 324.17500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

LGLLLRHLRHHSNLLANI

LGLLLRHLRHHSNLLANI (B18) is an 18 amino acid peptide. LGLLLRHLRHHSNLLANI derives from the membrane-associated protein binding. LGLLLRHLRHHSNLLANI shows a high affinity for Cu(2+) ions[1].

  • CAS Number: 222557-92-8
  • MF: C94H160N32O22
  • MW: 2090.48
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Jasmoside

Jasmoside is a secoiridoid glucoside, which can be isolated from leaves of Jasminum mesnyi[1].

  • CAS Number: 97763-17-2
  • MF: C43H60O22
  • MW: 928.92
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4,4'-Dihydroxybiphenyl-d8

4,4'-Dihydroxybiphenyl-d8 is the deuterium labeled 4,4'-Dihydroxybiphenyl[1].

  • CAS Number: 612480-60-1
  • MF: C12H2D8O2
  • MW: 194.25600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Aristola-1(10),8-dien-2-one

Aristola-1(10),8-dien-2-one is a sesquiterpene compound that can be isolated from rhizome of Nardostachys chinensis of Valerianaceae[1].

  • CAS Number: 22391-34-0
  • MF: C15H20O
  • MW: 216.32
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isoguaiacin

Isoguaiacin is a natural product[1].

  • CAS Number: 78341-26-1
  • MF: C20H24O4
  • MW: 328.4
  • Catalog: Others
  • Density: 1.151±0.06 g/cm3(Predicted)
  • Boiling Point: 484.5±45.0 °C(Predicted)
  • Melting Point: 198-200 °C
  • Flash Point: N/A

Theralizumab

Theralizumab (TGN1412) is a superagonist anti-CD28 monoclonal antibody that directly stimulates T cells. Theralizumab can be used for the research of rheumatoid arthritis[1][2].

  • CAS Number: 906068-56-2
  • MF:
  • MW:
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Coumarin

Coumarin is the primary bioactive ingredient in Radix Glehniae, named Beishashen in China, which possesses many pharmacological activities, including anticancer, anti-inflammation and antivirus activities.

  • CAS Number: 91-64-5
  • MF: C9H6O2
  • MW: 146.143
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 298.0±0.0 °C at 760 mmHg
  • Melting Point: 68-73 °C(lit.)
  • Flash Point: 118.3±16.1 °C

BTTAA-OH

BTTAA-OH is a kind of tris(triazolylmethyl)amine compound. BTTAA-OH has the potential for the research of labeling and/or imaging in living system (extracted from patent WO2012021390A1)[1].

  • CAS Number: 1257633-69-4
  • MF: C19H32N10O
  • MW: 416.52400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

HSL-IN-1

HSL-IN-1 (compound 24b) is a potent and orally active hormone sensitive lipase (HSL) inhibitor (IC50=2 nM) with a significantly reduced reactive metabolite liability[1].

  • CAS Number: 2095156-13-9
  • MF: C19H13BClF3N2O4
  • MW: 436.58
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg-OH trifluoroacetate salt

Laminin (925-933) is a peptide derived from residues 925-933 of the Laminin B1 chain that binds to the laminin receptor[1].

  • CAS Number: 110590-60-8
  • MF: C40H62N12O14S
  • MW: 967.06
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BI 6015

BI-6015 is a hepatocyte nuclear factor 4α (HNF4α) antagonist that can inhibit the expression of known HNF4α target genes. BI6015 represses insulin promoter activity through HNF4α antagonism. BI-6015 can be used for the research of cancer and diabetes[1].

  • CAS Number: 93987-29-2
  • MF: C15H13N3O4S
  • MW: 331.35
  • Catalog: Cancer
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 570.6±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 298.9±32.9 °C

Alagebrium chloride

Alagebrium chloride is an advanced glycation end product (AGE) inhibitor.

  • CAS Number: 341028-37-3
  • MF: C13H14ClNOS
  • MW: 267.77400
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A