Thromboxane B2-d4

Modify Date: 2024-01-10 18:09:00

Thromboxane B2-d4 Structure
Thromboxane B2-d4 structure
Common Name Thromboxane B2-d4
CAS Number 1346112-79-5 Molecular Weight 374.50500
Density N/A Boiling Point N/A
Molecular Formula C20H30D4O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thromboxane B2-d4


Thromboxane B2-D4 is the deuterium labeled Thromboxane B2. Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation[1][2].

 Names

Name (5Z,9β,13E,15S)-9,11,15-Trihydroxy(3,3,4,4-2H4)thromboxa-5,13-dien-1-oic acid

 Thromboxane B2-d4 Biological Activity

Description Thromboxane B2-D4 is the deuterium labeled Thromboxane B2. Thromboxane B2 is a prostaglandin derivative that is released during anaphylaxis. Thromboxane B2 induces arterial contraction and platelet aggregation[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Molecular Formula C20H30D4O6
Molecular Weight 374.50500
Exact Mass 374.26100
PSA 107.22000
LogP 2.76940