S186

Modify Date: 2024-01-19 20:01:28

S186 Structure
S186 structure
Common Name S186
CAS Number 97759-16-5 Molecular Weight 324.17500
Density N/A Boiling Point N/A
Molecular Formula C5H13CaNNaO7P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of S186


S186 is a kind of sodium salts of calcium-acetylpropylamine phosphonate(APA); a new strontium-specific chelating agent.IC50 value:Target: In a case test for 4 person who took 90Sr in due to an internal contaminated accident, the APAP was adminstrated intramuscularly once a day for 3 days, the increase excretion of 90Sr was obvious and no side effects was observed among them. Recently, S186 has also been approved by Shanghai Municipal Health Bureau for emergency medical use in China.

 Names

Name Phosphonic acid, [1-(acetylamino)propylidene]bis-, calcium sodium salt (1:1:1)
Synonym More Synonyms

 S186 Biological Activity

Description S186 is a kind of sodium salts of calcium-acetylpropylamine phosphonate(APA); a new strontium-specific chelating agent.IC50 value:Target: In a case test for 4 person who took 90Sr in due to an internal contaminated accident, the APAP was adminstrated intramuscularly once a day for 3 days, the increase excretion of 90Sr was obvious and no side effects was observed among them. Recently, S186 has also been approved by Shanghai Municipal Health Bureau for emergency medical use in China.
Related Catalog
References

[1]. Weihai Zhuo, et al. A Brief Review of Researches Related to Radiation Emergency Medicine at Fundan University, China. Radiation Emergency Medicine. 2012 Vol.1 No.1-2 7-10.

 Chemical & Physical Properties

Molecular Formula C5H13CaNNaO7P2
Molecular Weight 324.17500
Exact Mass 323.96900
PSA 163.78000

 Synonyms

S186
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