Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

1-O-Gentiobiosyl-3,7-dimethoxy-8-hydroxyxanthone

1-O-Gentiobiosyl-3,7-dimethoxy-8-hydroxyxanthone (Compound 18) is a natural product that can be isolated from Swertia mussotii[1].

  • CAS Number: 487040-33-5
  • MF: C27H32O16
  • MW: 612.53
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Biotin-TAT (47-57)

Biotin-TAT (47-57), biotin tagged TAT, is a transactivator of transcription. Biotin-TAT (47-57) is one of the most widely used PTDs into different primary cells is ATP- and temperature-dependent, indicating the involvement of endocytosis[1][2].

  • CAS Number: 1231898-25-1
  • MF: C74H132N34O16S
  • MW: 1786.12
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Trimethylolpropane ethoxylate triacrylate

Trimethylolpropane ethoxylate triacrylate (ETPTA) is a plasticizer that can be used synthesize nanocomposites[1].

  • CAS Number: 28961-43-5
  • MF: C21H32O9
  • MW: 428.473
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 498.5±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 212.2±28.8 °C

3-Butylidenephthalide

3-Butylidenephthalide (Butylidenephthalide) is a phthalic anhydride derivative identified in Ligusticum chuanxiong Hort, and has larvicidal activity (LC50 of 1.56 mg/g for Spodoptera litura larvae)[1].

  • CAS Number: 551-08-6
  • MF: C12H12O2
  • MW: 188.223
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 312.0±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 127.9±23.4 °C

Arjunic acid

Arjunic acid (Arjuntriterpenic acid) (compound 13) is a triterpenoid compound isolated from Sanguisorba officinalis L[1].

  • CAS Number: 31298-06-3
  • MF: C30H48O5
  • MW: 488.699
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 602.7±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 332.3±28.0 °C

Odoratisol B

Odoratisol B is a natural product that can be isolated from Machilus odoratissima NEES[1].

  • CAS Number: 891182-94-8
  • MF: C20H24O5
  • MW: 344.40
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

GHRF, mouse

GHRF, mouse, a mouse growth hormone-releasing factor, is a peptide containing 44 amino acids. GHRF, mouse stimulates the release and synthesis of growth hormone[1].

  • CAS Number: 125199-49-7
  • MF: C220H365N69O64S
  • MW: 5032.74
  • Catalog: Endocrinology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fumarate hydratase-IN-1

Fumarate hydratase-IN-1, an enzyme of the TCA cycle. Inhibition of fumarate hydratase-IN-1 can contribute to tumorigenicity in some cells. The use of a photoaffinity labeling strategy identified fumarate hydratase as the principal pharmacological target.[1]In vitro: The activity of this enzyme was measured using a well-established assay that monitored the conversion of fumarate into L-malate and subsequent oxidation of L-malate to oxaloacetate by malate dehydrogenase. Initial controls established that neither the carboxylic acid 3 nor ester 2 inhibited malate dehydrogenase Using this two-enzyme protocol we found that carboxylic acid 3 inhibited fumarate hydratase in a dose-dependent fashion in vitro. Besides, inhibition of fumarate hydratase can contribute to tumorigenicity in some cells.[1]

  • CAS Number: 1644060-37-6
  • MF: C27H30N2O4
  • MW: 446.538
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 693.0±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 372.9±31.5 °C

Fmoc-L-His(Boc)-OH

1-[(1,1-Dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-histidine is a histidine derivative[1].

  • CAS Number: 81379-52-4
  • MF: C26H27N3O6
  • MW: 477.509
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ivangustin

Ivangustin is a sesquiterpene isolated from the flower heads of the medicinal plant Inula britannica[1].

  • CAS Number: 14164-59-1
  • MF: C15H20O3
  • MW: 248.318
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 438.0±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 187.9±21.5 °C

D-Lysine monohydrochloride

D-Lysine monohydrochloride is an Lysine stereoisomer which can be used as a component of surfactants[1].

  • CAS Number: 7274-88-6
  • MF: C6H15ClN2O2
  • MW: 182.648
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 311.5ºC at 760 mmHg
  • Melting Point: 266ºC (dec.)
  • Flash Point: 142.2ºC

(2,4,6-trichloro-3-hydroxy-5-methoxyphenyl)methyl β-D-glucopyranoside

(2,4,6-Trichloro-3-hydroxy-5-methoxyphenyl)methyl β-D-glucopyranoside (Compound 1) is a chlorophenyl glycoside that can be isolated from Lilium regale. Lilium regale is used for research of lung ailments[1].

  • CAS Number: 2839363-14-1
  • MF: C14H17Cl3O8
  • MW: 419.64
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-D-tyrosine

Boc-D-Tyr-OH is a tyrosine derivative[1].

  • CAS Number: 70642-86-3
  • MF: C14H19NO5
  • MW: 281.304
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 484.9±40.0 °C at 760 mmHg
  • Melting Point: 135-140 °C
  • Flash Point: 247.1±27.3 °C

2-(Methyl-d3)phenol

2-(Methyl-d3)phenol is the deuterium labeled 2-(Methyl)phenol[1].

  • CAS Number: 70837-27-3
  • MF: C7H5D3O
  • MW: 111.15600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cyclolinopeptide B

Cyclolinopeptide B is a cyclic nonapeptide with immunosuppressive activity on human peripheral blood lymphocytes[1].

  • CAS Number: 193139-41-2
  • MF: C56H83N9O9S
  • MW: 1058.38
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Type A Allatostatin II

Allatostatin II is a decapeptid amine. Allatostatins are pleiotropic neuropeptides for inhibition of juvenile hormone synthesis in insects.

  • CAS Number: 123374-34-5
  • MF: C49H74N14O13
  • MW: 1067.20
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Olmesartan ethyl ester

Olmesartan ethyl ester (compound 11) is an Olmesartan impurity. Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist used to in the high blood pressure study[1].

  • CAS Number: 144689-23-6
  • MF: C26H30N6O3
  • MW: 474.55500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Wilfordine

Wilfordine is an alkaloid that isolated from the roots of Tripterygium wilfordii[1].

  • CAS Number: 37239-51-3
  • MF: C43H49NO19
  • MW: 883.844
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 895.5±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 495.4±34.3 °C

5,6-Dichlorovanillin

5,6-Dichlorovanillin is a product upon chlorination to afford 4,5,6-trichloroguaiacol, together with tetrachloroguaiacol and the unreacted starting materials[1].

  • CAS Number: 18268-69-4
  • MF: C8H6Cl2O3
  • MW: 221.037
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 313.9±37.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 143.7±26.5 °C

1-Hydroxyrutaecarpine

1-Hydroxyrutaecarpine (compound 1a) is a hydroxy-derivative of rutaecarpine. 1-Hydroxyrutaecarpine shows cytotoxicities with ED50s of 3.72, 7.44 µg/mL for P-388 and HT-29 cells, respectively. 1-Hydroxyrutaecarpine shows antiplatelet activity[1][2][3].

  • CAS Number: 53600-24-1
  • MF: C18H13N3O2
  • MW: 303.31
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 601.7±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 317.7±34.3 °C

Fluocinolone

Fluocinolone is a corticosteroid that is used to relieve redness, itching, swelling, or other discomfort caused by skin conditions[1].

  • CAS Number: 807-38-5
  • MF: C21H26F2O6
  • MW: 412.42400
  • Catalog: Inflammation/Immunology
  • Density: 1.45g/cm3
  • Boiling Point: 589ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 310ºC

Jionoside A1

Jionoside A1 isolated from Radix Rehmanniae Praeparata displays dose dependent immune-enhancement activity and possesses moderate protective activities on H2O2-treated SH-SY5Y cells[1].

  • CAS Number: 120444-60-2
  • MF: C36H48O20
  • MW: 800.76
  • Catalog: Inflammation/Immunology
  • Density: 1.61±0.1 g/cm3(Predicted)
  • Boiling Point: 1039.4±65.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

EIDD-1931-d2

EIDD-1931-d2 is the deuterium labeled 3,6-Dichloro-2-methoxybenzoic acid[1].

  • CAS Number: 1955549-12-8
  • MF: C9H11D2N3O6
  • MW: 261.23
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N6-[((1S,2R)-1-CARBOXY-2-HYDROXYBUTYLAMINO)CARBONYL]ADENOSINE SODIUM SALT

N6 - Threonylcarbamoyladenosine is a common nucleosides, which can decorate and become tRNA[1].

  • CAS Number: 24719-82-2
  • MF: C15H19N6NaO8
  • MW: 434.33700
  • Catalog: Others
  • Density: 1.96g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BIBR 1087 SE

BIBR 1087 SE is an intermediate metabolite of dabigatran etexilate.

  • CAS Number: 212321-78-3
  • MF: C32H37N7O5
  • MW: 599.680
  • Catalog: Inflammation/Immunology
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 853.4±75.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 469.9±37.1 °C

Ralmitaront

Ralmitaront (RO6889450), a potent and orally active partial agonist of the trace amine-associated receptor 1 (TAAR1), acts as a neuroleptic agent. Ralmitaront can be used for the research of neuro-related diseases, such as schizophrenia (SCZ), schizoaffective disorder, and negative symptoms[1].

  • CAS Number: 2133417-13-5
  • MF: C17H22N4O2
  • MW: 314.382
  • Catalog: Neurological Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 491.5±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 251.0±28.7 °C

DACN(Tos,Suc-NHS)

DACN(Tos,Suc-NHS) is a click chemistry reagent containing an azide group.

  • CAS Number: 2411082-26-1
  • MF: C22H25N3O7S
  • MW: 475.51
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,3,5-Trimethylphenol

2,3,5-Trimethylphenol is a phenolic compound[1].

  • CAS Number: 697-82-5
  • MF: C9H12O
  • MW: 136.19
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 231.1±9.0 °C at 760 mmHg
  • Melting Point: 92-95 °C(lit.)
  • Flash Point: 103.6±8.4 °C

MoTP

MoTP is a specific platelet activating factor receptor antagonist and can induce melanocyte ablation. MoTP can be used for the research of cancer.

  • CAS Number: 57055-82-0
  • MF: C14H21NO2S
  • MW: 267.387
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 424.9±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 210.8±27.3 °C

diisoamylamine

Diisoamylamine (Diisopentylamine) is a small molecule that can be used for wet etching[1].

  • CAS Number: 544-00-3
  • MF: C10H23N
  • MW: 157.29600
  • Catalog: Others
  • Density: 0,767 g/cm3
  • Boiling Point: 187-188°C
  • Melting Point: -44°C
  • Flash Point: 58°C