Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

(7-Methoxy-2-oxo-2H-chromen-4-yl)acetic acid

MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities[1][2].

  • CAS Number: 62935-72-2
  • MF: C12H10O5
  • MW: 234.205
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 472.9±45.0 °C at 760 mmHg
  • Melting Point: 193 °C (dec.)(lit.)
  • Flash Point: 189.2±22.2 °C

Gibberellin A1

Gibberellin A1 is a kind of plant hormones. Gibberellin A1 is a growth-promoting acids isolated from immature seed of Phaseolus multiflorus[1].

  • CAS Number: 545-97-1
  • MF: C19H24O6
  • MW: 348.390
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 619.7±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 227.0±25.0 °C

alefacept

Alefacept (BG 9273) is a human lymphocyte function-associated antigen 3/immunoglobulin 1 fusion protein. Alefacept can be used for the research of chronic plaque psoriasis[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Activated T Subunit

Activated T Subunit can be used in the synthesis of exon jumping oligomer conjugates. The oligomer conjugates complement selected target sites in the human anti-muscular atrophy protein gene and induce exon 51 jumping. It can be used for research of muscular dystrophy[1].

  • CAS Number: 1155373-34-4
  • MF: C31H34ClN4O5P
  • MW: 609.05
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(±)-Acuminatin

Acuminatin is a new bis-phenylpropide can be isolated from Magnolia acuminata L[1].

  • CAS Number: 72881-08-4
  • MF: C21H24O4
  • MW: 340.41
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5,6,7-Trimethoxycoumarin

5,6,7-Trimethoxycoumarin is a coumarin that can be isolated from Artemisia apiacea[1].

  • CAS Number: 55085-47-7
  • MF: C12H12O5
  • MW: 236.22
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5,7,8,3′,4′,5′-Hexamethoxyflavone

5,7,8,3′,4′,5′-Hexamethoxyflavone is a flavonoid that can be isolated from the fresh ripe fruits of Murraya paniculata[1].

  • CAS Number: 80324-51-2
  • MF: C21H22O8
  • MW: 402.39500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DSPE-succinic acid

DSPE-succinic acid is a phophalipid capped with a carboxylic acid moiety. The carboxylic acid moiety is reactive with amine to from a stable amide linkage. DSPE-succinic acid can be used to prepare nanoparticles or liposomes for drug nanocarrier to deliver therapeutics[1].

  • CAS Number: 248253-94-3
  • MF: C45H86NO11P
  • MW: 848.14
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2’-O-(2-Azidoethyl)adenosine

2’-O-(2-Azidoethyl)adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 2226475-42-7
  • MF: C12H16N8O4
  • MW: 336.31
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Kayexalate

Kayexalate, a cation-exchange resin, is an orally active plasma potassium inhibitor. Kayexalate can be used in the research of hyperkalemia[1][2].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Imidacloprid-urea

Imidacloprid-urea is a metabolite of Imidacloprid. Imidacloprid is an effective and widely used neonicotinoid pesticide to control pests of cereals, vegetables, tea and cotton. Imidacloprid-urea can occupy or block adsorption sites of imidacloprid on soil, potentially affecting the fate, transport, and bioavailability of imidacloprid in the environment[1].

  • CAS Number: 120868-66-8
  • MF: C9H10ClN3O
  • MW: 211.64800
  • Catalog: Others
  • Density: 1.359g/cm3
  • Boiling Point: 478.388ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 243.12ºC

Tanshinoic acid A

Tanshinoic acid A, a oxidic tanshinone diterpenoid, is a 11,12-seco-tanshinone derivative[1].

  • CAS Number: 2569515-88-2
  • MF: C18H14O5
  • MW: 310.30
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

dihydrocubebin

Dihydrocubebin is a compound isolated from Piper cubeba as potent and selective inhibitors against cytochrome P450 3A4 (CYP3A4)[1].

  • CAS Number: 24563-03-9
  • MF: C20H22O6
  • MW: 358.38500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Orotidine

Orotidine is an intermediate in pyrimidine nucleotide biosynthesis in RNA and DNA, and plays a crucial role in contemporary biology.

  • CAS Number: 314-50-1
  • MF: C10H12N2O8
  • MW: 288.211
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 200ºC
  • Flash Point: N/A

(R)-Phenylglycine tert-butyl ester hydrochloride

(R)-Phenylglycine tert-butyl ester hydrochloride is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 256478-95-2
  • MF: C12H18ClNO2
  • MW: 243.730
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(3β,13α)-Pimara-8(14),15-dien-3-ol

Sandaracopimaradien-3β-ol is a natural isopimarane-type diterpenoid[1].

  • CAS Number: 4728-30-7
  • MF: C20H32O
  • MW: 288.47
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 373.7±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 160.8±20.1 °C

16-Epivoacarpine

16-Epivoacarpine is a natural alkaloid isolated from Gelsemium elegans[1].

  • CAS Number: 114027-38-2
  • MF: C21H24N2O4
  • MW: 368.426
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 548.9±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 285.8±30.1 °C

Decanoic anhydride

Decanoic Anhydride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 2082-76-0
  • MF: C20H38O3
  • MW: 326.51400
  • Catalog: Others
  • Density: 0.886 g/mL at 25 °C(lit.)
  • Boiling Point: 125-140 °C0.05 mm Hg(lit.)
  • Melting Point: 24-25 °C(lit.)
  • Flash Point: >230 °F

N-Boc-N'-nitro-L-arginine

Boc-Arg(NO2)-OH is an arginine derivative[1].

  • CAS Number: 2188-18-3
  • MF: C11H21N5O6
  • MW: 319.314
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 257ºC
  • Flash Point: N/A

C24:1-Ceramide

C24:1-Ceramide is one of the most abundant naturally occurring ceramide. Ceramides regulates many diverse biological activities, such as cell apoptosis, cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain[1][2][3].

  • CAS Number: 54164-50-0
  • MF: C42H81NO3
  • MW: 648.097
  • Catalog: Apoptosis
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 749.6±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 407.1±32.9 °C

Thevetiaflavone

Thevetiaflavone could upregulate the expression of Bcl‑2 and downregulate that of Bax and caspase‑3.

  • CAS Number: 29376-68-9
  • MF: C16H12O5
  • MW: 284.263
  • Catalog: Bcl-2 Family
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 567.9±50.0 °C at 760 mmHg
  • Melting Point: 263℃
  • Flash Point: 218.3±23.6 °C

Benzyl acetate

Benzyl acetate is a constituent of jasmin and of the essential oils of ylang-ylang and neroli. Natural sources of Benzyl acetate include varieties of flowers like jasmine (Jasminum), and fruits like pear, apple[1].

  • CAS Number: 140-11-4
  • MF: C9H10O2
  • MW: 150.174
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 213.5±0.0 °C at 760 mmHg
  • Melting Point: −51 °C(lit.)
  • Flash Point: 102.2±0.0 °C

C-6 NBD-dihydro-Ceramide

C-6 NBD-dihydro-Ceramide is a membrane-permeable ceramides. C-6 NBD-dihydro-Ceramide is a biologically active fluorescent analog of short chain[1][2].

  • CAS Number: 114301-95-0
  • MF: C30H51N5O6
  • MW: 577.75600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hippuryl-Phe-Arg-OH

Hippuryl-Phe-Arg-OH is the active site on the cell surface of Angiotensin I converting enzyme (ACE)[1].

  • CAS Number: 73167-83-6
  • MF: C24H30N6O5
  • MW: 482.53200
  • Catalog: Others
  • Density: 1.33g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Enalaprilat D5

Enalaprilat D5 is the deuterium labeled Enalaprilat(MK-422), which is an angiotensin-converting enzyme (ACE) inhibitor.

  • CAS Number: 349554-00-3
  • MF: C18H19D5N2O5
  • MW: 353.424
  • Catalog: Angiotensin-converting Enzyme (ACE)
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 601.0±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 317.3±31.5 °C

CD 2665

CD2665 is a selective RAR-beta/gamma antagonist, with Ki values of 110 nM, 306 nM for RARγ and RARβ, respectively[1].

  • CAS Number: 170355-78-9
  • MF: C31H34O5
  • MW: 486.59900
  • Catalog: RAR/RXR
  • Density: 1.227g/cm3
  • Boiling Point: 668.6ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 219.3ºC

Z-Ser(Bzl)-OH

Z-Ser(Bzl)-OH is a serine derivative[1].

  • CAS Number: 20806-43-3
  • MF: C18H19NO5
  • MW: 329.347
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 537.1±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 278.6±30.1 °C

H-Lys(Tfa)-OH

H-Lys(Tfa)-OH is a lysine derivative[1].

  • CAS Number: 10009-20-8
  • MF: C8H13F3N2O3
  • MW: 242.196
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 382.5±42.0 °C at 760 mmHg
  • Melting Point: 258ºC
  • Flash Point: 185.1±27.9 °C

3,5-Dichlorobiphenyl-2′,3′,4′,5′,6′-d5

3,5-Dichlorobiphenyl-2′,3′,4′,5′,6′-d5 is the deuterium labeled 3,5-Dichlorobiphenyl[1].

  • CAS Number: 1276197-28-4
  • MF: C12H3D5Cl2
  • MW: 228.13
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

WAY-297848

WAY-297848 is an active molecule for the study of amyloid diseases and synucleinopathies.

  • CAS Number: 404360-27-6
  • MF: C13H13ClN2O2S
  • MW: 296.77
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A