Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Z-MeLeu-OH

(S)-2-(((Benzyloxy)carbonyl)(methyl)amino)-4-methylpentanoic acid is a leucine derivative[1].

  • CAS Number: 33099-08-0
  • MF: C7H15NO2
  • MW: 145.199
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 226.1±23.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 90.6±22.6 °C

(10E)-10-Heptadecenoic acid

trans-10-Heptadecenoic acid is a trans-fatty acid. trans-10-Heptadecenoic acid synthesizes polyhydroxy-chain alkanoates under the action of 2, 4-dienyl-CoA reductase and Delta3, Delta2-enyl-CoA isomerase. In the absence of 2, 4-dienyl-CoA reductase, trans-10-Heptadecenoic acid is degraded by enyl-CoA hydratase II of the multifunctional enzyme (MFE). trans-10-Heptadecenoic acid leads to massive intracellular carbon outflow through reductase dependent and direct MFE dependent pathways[1].

  • CAS Number: 126761-43-1
  • MF: C17H32O2
  • MW: 268.43
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 354.0±11.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 250.9±14.4 °C

7-Ethoxycoumarin

7-Ethoxycoumarin is a substrate for cytochrome P450(CYP450) and has been used in the functional characterization of various CYPs[1].

  • CAS Number: 31005-02-4
  • MF: C11H10O3
  • MW: 190.195
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 345.0±37.0 °C at 760 mmHg
  • Melting Point: 88-90 °C(lit.)
  • Flash Point: 143.1±21.1 °C

Thioredoxin reductase peptide

Thioredoxin reductase peptide corresponds to residues 53–67 in thioredoxin reductase (TrxR), used in thioredoxin reductase research. Thioredoxin reductase acts as a reductant of disulfide-containing proteins and plays crucial role in cellular antioxidant defense[1][2].

  • CAS Number: 950890-23-0
  • MF: C66H106N18O18S2
  • MW: 1503.79
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-Carboxyrhodamine 6G, succinimidyl ester (5-CR 6G, SE)

5-Carboxyrhodamine 6G succinimidyl ester (R6G-SE) is an amine reactive fluorescent dye[1].

  • CAS Number: 209112-21-0
  • MF: C33H34ClN3O7
  • MW: 620.092
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Benzyltrimethylammonium hydroxide

Triton B is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 100-85-6
  • MF: C10H17NO
  • MW: 167.25
  • Catalog: Others
  • Density: 1.059 g/mL at 25 °C
  • Boiling Point: 65°C
  • Melting Point: -98ºC
  • Flash Point: 60 °F

LipidGreen 2

LipidGreen 2 is a second generation small molecule probe for lipid imaging. LipidGreen2 has a better fluorescence signal compared with the previous LipidGreen, and selectively stains neutral lipids in cells and fat deposits in live zebrafish[1].

  • CAS Number: 1382764-52-4
  • MF: C22H29NO4
  • MW: 371.47
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ubiquinone-1

Ubiquinone-1 is an intermediate in the synthesis of Coenzyme Q.

  • CAS Number: 727-81-1
  • MF: C14H18O4
  • MW: 250.29000
  • Catalog: Others
  • Density: 1.1g/cm3
  • Boiling Point: 389.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 172ºC

Hsp70-derived octapeptide

Hsp70-derived octapeptide is a conserved octapeptide of the C-terminal end of Hsp70, which physically interacts with tetratricopeptide repeat (TPR) motifs[1][2].

  • CAS Number: 736171-62-3
  • MF: C36H58N8O16
  • MW: 858.89
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

alpha-d-mannopyranosylphenyl isothiocyanate

4-Isothiocyanatophenyl α-D-Mannopyranoside, an organic isothiocyanate, is a building block and reagent which is used for preparing neoglycoproteins[1].

  • CAS Number: 96345-79-8
  • MF: C13H15NO6S
  • MW: 313.32600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 180-181ºC
  • Flash Point: N/A

WAY-351783

WAY-351783 is an active molecule.

  • CAS Number: 460994-47-2
  • MF: C15H12BrNO5S
  • MW: 398.23
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

OG 488, acid

OG 488, acid, a fluorescent pH indicator, has many applications in biochemistry and neurosciences[1].

  • CAS Number: 195136-52-8
  • MF: C21H10F2O7
  • MW: 412.30
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(2H3)Acetamide

Acetamide-2,2,2-d3 is the deuterium labeled Acetamide-2,2,2-d3[1].

  • CAS Number: 23724-60-9
  • MF: C2H2D3NO
  • MW: 62.086
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 221.1±0.0 °C at 760 mmHg
  • Melting Point: 78-80ºC(lit.)
  • Flash Point: 90.1±18.4 °C

DiOC16(3)

DiOC16(3) (3,3'-Dihexadecyloxacarbocyanine) is a lipophilic carbocyanine dye used primarily for optical recordings of membrane voltage and studies of membrane fluidity.

  • CAS Number: 161433-32-5
  • MF: C49H77ClN2O6
  • MW: 825.60
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Pisatin

(S,S)-Pisatin (compound 8) is a dimeric pterocarpan derivative is isolated from the grains of millettia pachyloba[1][2].

  • CAS Number: 20186-22-5
  • MF: C17H14O6
  • MW: 314.289
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 483.0±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 245.9±28.7 °C

5-Fluoro-2′-deoxy-UTP sodium

5-Fluoro-2′-deoxy-UTP sodium can be used as a substrate for DNA synthesis[1].

  • CAS Number: 1630828-71-5
  • MF: C9H14FN2O14P3.xNa
  • MW:
  • Catalog: DNA/RNA Synthesis
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Arundamine

Arundamine is a nature product. Arundamine can be isolated from roots of Arundo donax L[1].

  • CAS Number: 475977-53-8
  • MF: C23H28N4O
  • MW: 376.49
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hexa-L-Tyrosine

Tyr-Tyr-Tyr-Tyr-Tyr-Tyr is a tyrosine derivative[1].

  • CAS Number: 6934-38-9
  • MF: C54H56N6O13
  • MW: 997.05500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Lucifer Yellow CH dilithium salt

Lucifer Yellow CH dilithium salt is a highly fluorescent dye that is useful in marking nerve cells[1]. Lucifer Yellow CH dilithium salt is assumed to be nontoxic, and it is membrane impermeable and highly dissociated at physiological pH values[2][3].

  • CAS Number: 67769-47-5
  • MF: C13H9Li2N5O9S2
  • MW: 457.25100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Methyl 1,2,3,4-tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetate

Methyl 1,2,3,4-tetrahydro-α-hydroxy-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidineacetate is a pyrimidine nucleoside analog. Pyrimidine nucleoside analogs have a wide range of biochemical and anticancer activities. These include DNA synthesis inhibition, RNA synthesis inhibition, antiviral effects, and immunomodulatory effects[1].

  • CAS Number: 945684-13-9
  • MF: C12H16N2O9
  • MW: 332.26344
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Aristolindiquinone

Aristolindiquinone can be isolated from Aristolwhia indica[1].

  • CAS Number: 86533-36-0
  • MF: C12H10O4
  • MW: 218.20500
  • Catalog: Others
  • Density: 1.452g/cm3
  • Boiling Point: 400.9ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 210.4ºC

Hexylene glycol

Hexylene glycol is a small molecular weight surfactant, widely used as an industrial coating solvent, does not cause adverse health or environmental effects.

  • CAS Number: 107-41-5
  • MF: C6H14O2
  • MW: 118.174
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 197.5±0.0 °C at 760 mmHg
  • Melting Point: −40 °C(lit.)
  • Flash Point: 93.9±0.0 °C

N-LAUROYLSARCOSINE

N-lauroylsarcosine (NLS) is an anionic surfactant, and can be used as a permeation enhancer. The mixture of NLS in 25–50% ethanol acts synergistically to increase skin permeability, which may be useful for transdermal drug delivery research[1].

  • CAS Number: 97-78-9
  • MF: C15H29NO3
  • MW: 271.39600
  • Catalog: Others
  • Density: 0.986g/cm3
  • Boiling Point: 413.2ºC at 760mmHg
  • Melting Point: 45-49 °C
  • Flash Point: N/A

(2α,3β)-2,3,24-Trihydroxyurs-12-en-28-oic acid

2α,3β,24-Trihydroxyurs-12-en-28-oic acid is a natural product that can be isolated from Salvia palaestina[1].

  • CAS Number: 143839-02-5
  • MF: C30H48O5
  • MW: 488.699
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 609.4±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 336.4±28.0 °C

diSulfo-Cy3 alkyne

diSulfo-Cy3 alkyne is a water-soluble dye and a Click Chemistry reagent containing an azide group. Absorbance and emission of the dye are identical to Cy3 fluorophore. diSulfo-Cy3 alkyne can be used for the labeling of proteins, and even intact biological objects in water phase[1].

  • CAS Number: 2055138-88-8
  • MF: C33H38N3NaO7S2
  • MW: 675.79
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fluorogen binding modulator-1

Fluorogen binding modulator-1 (PubChem SID 125240934) is a fluorogen activating protein (FAP)-fluorogen binding modulator with -log EC50s of 6.61 and 6.37 for AM2.2-β2AR and AM2.2-GPR32, respectively[1].

  • CAS Number: 510716-65-1
  • MF: C16H22ClN3O5S
  • MW: 403.88
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Substance P (1-9)

Substance P (1-9) is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder.

  • CAS Number: 57468-17-4
  • MF: C52H77N15O12
  • MW: 1104.26000
  • Catalog: Peptides
  • Density: 1.46 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Kemptide (amide)

Kemptide (amide) is a heptapeptide with properties of a cytophilic substrate. Kemptide is a molecule preserving cell membrane intactness, is phosphorylated by PKI, the inhibitory protein specific for cAMP-dependent protein kinase (PK)[1].

  • CAS Number: 70691-36-0
  • MF: C32H62N14O8
  • MW: 770.92400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Aminoethan-1-ol-13c2 hydrochloride

2-Aminoethan-1-ol-13C2 hydrochloride is the 13C labeled 2-Aminoethan-1-ol hydrochloride[1].

  • CAS Number: 1173019-25-4
  • MF: C2H8ClNO
  • MW: 99.52930
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 84 - 86 °C - lit.
  • Flash Point: N/A

Suc-Phe-Ala-Ala-Phe-pNA

Suc-Phe-Ala-Ala-Phe-pNA (Suc-FAAF-pNA) is a synthetic polypeptide that can serve as a substrate for the protease from Aeribacillus pallidus VP3 (SPVP), the serine alkaline protease from Caldicoprobacter guelmensis (SAPCG) strain D2C22T, the alcalase ultra 2.5 L and the thermolsyin type X[1].

  • CAS Number: 110906-89-3
  • MF: C34H38N6O9
  • MW:
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A