Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Sulfabenzamide

Sulfabenzamide is a intermediate in the synthesis of organic and pharmaceutical.

  • CAS Number: 127-71-9
  • MF: C13H12N2O3S
  • MW: 276.311
  • Catalog: Autophagy
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 180-184 °C
  • Flash Point: N/A

Connexin mimetic peptide 40,37GAP26

Connexin mimetic peptide 40,37GAP26 is a biological active peptide. (This peptide corresponds to the GAP26 domain of the extracellular loop of the major vascular connexins (Cx37, Cx40), designated as 37, 40Gap 26 according to Cx homology. It was used to investigate the role of gap junctions in the spread of endothelial hyperpolarizations evoked by cyclopiazonic acid (CPA) through the wall of the rodent iliac artery. The gap junction plaques constructed from Cx37 and Cx40 were abundant in the endothelium. This peptide provides inhibitory effects against subintimal hyperpolarization.)

  • CAS Number: 514787-21-4
  • MF: C70H105N19O19S
  • MW: 1548.76
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Methyltetrazine-amido-N-bis(PEG4-acid)

Methyltetrazine-amido-N-bis(PEG4-acid) is a click chemistry reagent containing an azide group. Methyltetrazine-amido-N-bis(PEG4-acid) is a PEG derivative that contains a methyltetrazine group and two acid groups. This reagent can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. PEG linker increases the water solubility of the compound. Reagent grade, for research use only[1].

  • CAS Number: 2639395-39-2
  • MF: C33H51N5O13
  • MW: 725.8
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Bromobutanoic acid-d6

2-Bromobutanoic acid-d6 is the deuterium labeled 2-Bromobutanoic acid[1].

  • CAS Number: 1219799-08-2
  • MF: C4HD6BrO2
  • MW: 173.04
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Integrin Binding Peptide

Integrin Binding Peptide is derived by fibronectin. Integrin Binding Peptide can be used for PEG hydrogel preparation[1][2].

  • CAS Number: 278792-07-7
  • MF: C42H63N15O16S
  • MW: 1066.105
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-BENZOTHIAZOLESULFENAMIDE, N-CYCLOHEXYL

Thiohexam is a rubber cure accelerator. Thiohexam is also a known allergen and dermatological sensitizer[1].

  • CAS Number: 95-33-0
  • MF: C13H16N2S2
  • MW: 264.409
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 410.4±28.0 °C at 760 mmHg
  • Melting Point: 93-100°C
  • Flash Point: 202.0±24.0 °C

Delta-Gluconolactone

D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activity.

  • CAS Number: 90-80-2
  • MF: C6H10O6
  • MW: 178.140
  • Catalog: PROTAC Linker
  • Density: 0.6
  • Boiling Point: 230.35°C
  • Melting Point: 151-155 ºC
  • Flash Point: 192.3±20.3 °C

Berninamycin D

Berninamycin D is a cyclic peptide fungal metabolite isolated from ermentation of Streptomyces bernensis[1].

  • CAS Number: 161263-50-9
  • MF: C45H45N13O13S
  • MW: 1007.983
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Chlorobenzaldehyde-2,3,5,6-d4

4-Chlorobenzaldehyde-2,3,5,6-d4 is the deuterium labeled 4-Chlorobenzaldehyde[1].

  • CAS Number: 62285-59-0
  • MF: C7HClD4O
  • MW: 144.59200
  • Catalog: Others
  • Density: 1.278g/cm3
  • Boiling Point: 213-214ºC(lit.)
  • Melting Point: 45-50ºC(lit.)
  • Flash Point: 87.8ºC

(Arg6)-Amyloid β-Protein (1-40) trifluoroacetate salt

[Arg6]-β-Amyloid (1-40), england mutation is a biological active peptide. (Several mutations in the beta amyloid precursor gene cause autosomal dominant Alzheimer's Disease in a number of kindreds. Among them, the English mutation, with His at position 6 replaced with Arg, was reported to accelerate the kinetics of oligomers formation which act as fibril seeds and are more toxic to cultured neuronal cells.)

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

S-Adenosyl-L-Methtonine

S-Adenosyl-DL-methionine is a derivative of Ademetionine (HY-B0617). Ademetionine is an intermediate metabolite of methionine[1].

  • CAS Number: 17176-17-9
  • MF: C15H22N6O5S
  • MW: 570.639
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-D-Phg(4-Cl)-OH

H-D-Phg(4-Cl)-OH is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 43189-37-3
  • MF: C8H8ClNO2
  • MW: 185.608
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 328.8±32.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 152.7±25.1 °C

X-glucuronide CHA salt

X-Gluc cyclohexanamine is a dye reagent for the detection of β-glucuronidase (GUS), an enzyme produced by E. coli. X-Gluc cyclohexanamine can be used to detect E. coli contamination in food, water and the urinary tract (GUS as a specific detection indicator). X-Gluc cyclohexanamine is also widely used in molecular biology experiments to label and detect the expression of target genes (reacts with the GUS gene, appears blue)[1].

  • CAS Number: 114162-64-0
  • MF: C20H26BrClN2O7
  • MW: 521.787
  • Catalog: Others
  • Density: 1.4241 (rough estimate)
  • Boiling Point: 732.2ºC at 760 mmHg
  • Melting Point: 228-230ºC
  • Flash Point: 396.6ºC

L-Cystine-d4

L-Cystine-d4 is the deuterium labeled L-Cystine. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes.

  • CAS Number: 1192736-38-1
  • MF: C6H8D4N2O4S2
  • MW: 244.33
  • Catalog: Ferroptosis
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Lys(Dnp)-OH

Fmoc-Lys(Dnp)-OH is a lysine derivative[1].

  • CAS Number: 148083-64-1
  • MF: C27H26N4O8
  • MW: 534.517
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 805.3±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 440.8±34.3 °C

Lauryl glucoside

Dodecyl β-D-glucopyranoside is a non-ionic detergent and surfactant commonly used to solubilize and purify membrane proteins in biochemical research. Dodecyl β-D-glucopyranoside also interacts with bovine serum albumin (BSA) to quench its intrinsic fluorescence. The critical micelle concentration (CMC) of Dodecyl β-D-glucopyranoside (DG) and DG/BSA complex is 2.0 mM and 2.34 mM, respectively. Micelles can be formed in aqueous solutions above this concentration[1].

  • CAS Number: 59122-55-3
  • MF: C18H36O6
  • MW: 348.475
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 499.1±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 255.6±28.7 °C

6-CARBOXY-X-RHODAMINE SUCCINIMIDYL ESTE

ROX NHS ester, 6-isomer is a highly fluorescent, and photostable rhodamine dye for various applications. ROX labeled oligonucleotide probes are often used in qPCR, and qPCR instruments have ROX channel. This is reactive dye for the labeling of amino-groups in peptides, proteins, and amino-oligonucleotides. Pure single isomer.

  • CAS Number: 117491-83-5
  • MF: C37H33N3O7
  • MW: 631.67
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cyanine3 carboxylic acid

Cyanine3 carboxylic acid chloride is a non-toxic red fluorescent dye with good solubility in organic solvents. Cyanine3 carboxylic acid chloride can be used as a non-reactive fluorophore for experimental control and calibration. Cyanine3 carboxylic acid chloride can also be synthesized with targeted drugs as fluorescent probes for rapid detection of drug reactions[1].

  • CAS Number: 1032678-01-5
  • MF: C30H37ClN2O2
  • MW: 493.080
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Hyp(tBu)-OH

Fmoc-Hyp(tBu)-OH is a proline derivative[1].

  • CAS Number: 122996-47-8
  • MF: C24H27NO5
  • MW: 409.475
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 578.6±50.0 °C at 760 mmHg
  • Melting Point: -63ºC
  • Flash Point: 303.7±30.1 °C

Pyrrhocoricin

Pyrrhocoricin is a biological active peptide. (Antimicrobial activity against Gram-negative bacteria)

  • CAS Number: 224569-84-0
  • MF: C119H190N34O38
  • MW: 2704.99
  • Catalog: Bacterial
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Excoecafolin C

5-Dexyexcoecafolin B is a tigliane-type diterpenoid isolated from the EtOAc extract of Excoecaria acerifolia Didr. 5-Dexyexcoecafolin B has anti-HIV-1 activity with a EC50 value of 0.036 μM[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-Aminofluorescein

5-Aminofluorescein (5-AF) is a new fluorescence marker, covalently bound to human serum albumin (AFL-HSA) [1]5-aminofluorescein is a pH-sensitive biomaterial, is the targeted prodrug for synthesis of FA-FITC-Arg-PTX and FA-5AF- Glu-PTX..

  • CAS Number: 3326-34-9
  • MF: C20H13NO5
  • MW: 347.321
  • Catalog: Dye Reagents
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 695.3±55.0 °C at 760 mmHg
  • Melting Point: 223ºC
  • Flash Point: 374.3±31.5 °C

Dehydronuciferine

Dehydronuciferine is isolated from the leaves of Nelumbo nucifera Gaertn, a acetylcholinesterase (AChE) inhibitor with an IC50 of 25 μg/mL[1].

  • CAS Number: 7630-74-2
  • MF: C19H19NO2
  • MW: 293.360
  • Catalog: AChE
  • Density: 1.193±0.06 g/cm3
  • Boiling Point: 493.0±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 190.9±17.3 °C

Ac-Asp(OtBu)-OH

AC-Asp(OtBU)-OH is an aspartic acid derivative[1].

  • CAS Number: 117833-18-8
  • MF: C10H17NO5
  • MW: 231.246
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 449.6±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 225.7±27.3 °C

(Bromomethyl)cyclohexane-d11

(Bromomethyl)cyclohexane-d11 is the deuterium labeled (Bromomethyl)cyclohexane[1].

  • CAS Number: 1219794-79-2
  • MF: C7H13Br
  • MW: 177.082
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 175.6±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 57.2±0.0 °C

Quercetin 3-O-beta-D-xylopyranoside

Reynoutrin (Quercetin-3-D-xyloside) is a flavonoid from Psidium cattleianum, with antioxidant and radical-scavenging activity[1].

  • CAS Number: 549-32-6
  • MF: C20H18O11
  • MW: 434.35
  • Catalog: Others
  • Density: 1.9±0.1 g/cm3
  • Boiling Point: 828.1±65.0 °C at 760 mmHg
  • Melting Point: 201-203℃
  • Flash Point: 296.3±27.8 °C

Baliforsen

Baliforsen is an antisense oligonucleotide (16 nucleotides) designed to target myotonic dystrophy protein kinase (DMPK) mRNA and treat myotonic dystrophy.

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Dihydroisocucurbitacin B

Dihydroisocucurbitacin B is an active compound. Dihydroisocucurbitacin B can be extracted from the roots of Wilbrandia ebracteata[1].

  • CAS Number: 68354-21-2
  • MF: C32H48O8
  • MW: 560.719
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 695.3±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 216.5±25.0 °C

Fmoc-N-Me-Leu-OH

Fmoc-N-Me-Leu-OH, an N-Fmoc-N-methyl amino acid, is available for the peptide-coupling reaction.

  • CAS Number: 103478-62-2
  • MF: C22H25NO4
  • MW: 367.438
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 537.3±29.0 °C at 760 mmHg
  • Melting Point: 113-116ºC
  • Flash Point: 278.7±24.3 °C

Naloxone-d5

Naloxone D5 is deuterium labeled Naloxone. Naloxone is a a potent opioid receptor antagonist.

  • CAS Number: 1261079-38-2
  • MF: C19H16D5NO4
  • MW: 332.41
  • Catalog: Opioid Receptor
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: >155°C (分解)
  • Flash Point: N/A