Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

2-Oxo-2H-pyran-5-carboxylic acid

Coumalic acid is a valuable platform compound which can be prepared from malic acid. Coumalic acid can be used in the flavours, fragrances and cosmetics industries, as polymer components, and as pharmaceutical scaffolds displaying anti-bronchial and -malarial activity[1].

  • CAS Number: 500-05-0
  • MF: C6H4O4
  • MW: 140.094
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 282.4±0.0 °C at 760 mmHg
  • Melting Point: 203-205 °C (dec.)(lit.)
  • Flash Point: 137.3±19.4 °C

β,β-Dimethylacrylalkannin

(Rac)-Arnebin 1 ((Rac)-β,β-Dimethylacrylalkannin) is the racemate of β,β-Dimethylacrylalkannin and/or β,β-Dimethylacrylshikonin. β,β-Dimethylacrylalkannin and β,β-Dimethylacrylshikonin are napthoquinones isolated from Arnebia nobilis. β,β-Dimethylacrylshikonin has anti-tumor activity[1].

  • CAS Number: 5162-01-6
  • MF: C21H22O6
  • MW: 370.39600
  • Catalog: Others
  • Density: 1.269g/cm3
  • Boiling Point: 587.345 °C
  • Melting Point: N/A
  • Flash Point: 206.409 °C

cyanidin

Cyanidin, an antioxidant, has protective effect on DNA cleavage, free radical scavenging activity and significant inhibition of XO activity[1].

  • CAS Number: 13306-05-3
  • MF: C15H11O6
  • MW: 287.244
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Netupitant N-Oxide

Netupitant N-oxide is the metabolite of Netupitant, which is a highly selective NK1 receptor antagonist.

  • CAS Number: 910808-11-6
  • MF: C30H32F6N4O2
  • MW: 594.59100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Beauveriolide III

Beauveriolide III is an inhibitor of lipid droplet formation in mouse macrophages[1].

  • CAS Number: 221111-70-2
  • MF: C27H41N3O5
  • MW: 487.632
  • Catalog: Metabolic Disease
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 777.3±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 423.9±32.9 °C

Mebendazole-d3

Mebendazole-d3 is the deuterium labeled L-Methionine-34S[1].

  • CAS Number: 1173021-87-8
  • MF: C16H10D3N3O3
  • MW: 298.31
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-Hydroxycytosine-13C,15N2

5-Hydroxycytosine-13C,15N2 is the 13C and 15N labeled 5-Hydroxycytosine[1].

  • CAS Number: 181516-92-7
  • MF: C313CH5N15N2O2
  • MW: 130.08
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Exendin-3 trifluoroacetate salt

Exendin-3 is a biologically active peptides isolated from venoms of the Gila monster lizards, Heloderma horridurn .

  • CAS Number: 130357-25-4
  • MF: C184H282N50O61S
  • MW: 4202.57
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,1'-Diethyl-2,2'-carbocyanine iodide

Pinacyanol iodide is a fluorescent cyanine dye. Pinacyanol iodide exhibits ultrafast excited state isomerization[1].

  • CAS Number: 605-91-4
  • MF: C25H25IN2
  • MW: 480.384
  • Catalog: Others
  • Density: 1.151g/cm3
  • Boiling Point: 527.7ºC at 760 mmHg
  • Melting Point: 295 °C (dec.)(lit.)
  • Flash Point: 240.2ºC

2,3-Dihydroxy-3-(4-hydroxyphenyl)propanoic acid

3-Hydroxy-3-(4-hydroxyphenyl)-lactic acid is a key metabolite in the P. roqueforti fermentation approach, with quantitative data of 10.2 ± 1.1 µM in Tyr1 (presence of L-tyrosine) of [1].

  • CAS Number: 100201-57-8
  • MF: C9H10O5
  • MW: 198.17
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 489.8±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 264.1±25.2 °C

Trx-red

Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm)[1].

  • CAS Number: 2368978-96-3
  • MF: C29H32ClN3O12S2
  • MW: 714.16
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

MPG peptides, Pβ

MPG peptides, Pβ is a primary amphiphilic peptide consisting of three domains[1].

  • CAS Number: 791642-10-9
  • MF: C129H208N36O32S
  • MW: 2807.32
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Gatralimab

Gatralimab (GZ-402668) is an IgG1 anti-CD52 monoclonal antibody[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-Glu-OtBu

Boc-Glu-OtBu is a glutamic acid derivative[1].

  • CAS Number: 24277-39-2
  • MF: C14H25NO6
  • MW: 303.351
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 449.8±40.0 °C at 760 mmHg
  • Melting Point: 113 °C
  • Flash Point: 225.8±27.3 °C

Aplodan

Aplodan is an antiischemic and antiarrhythmic agent. Aplodan has a protective action on cell membrane. Aplodan has the potential for the research of ischemic heart or ischemic heart disease with persistent ventricular premature beats (VPB) [1][2].

  • CAS Number: 6903-79-3
  • MF: C4H12N3O4P
  • MW: 197.130
  • Catalog: Cardiovascular Disease
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 384.1±52.0 °C at 760 mmHg
  • Melting Point: 244 °C(dec.)
  • Flash Point: 186.1±30.7 °C

Boc-O-benzyl-D-threonine

Boc-D-Thr(Bzl)-OH is a threonine derivative[1].

  • CAS Number: 69355-99-3
  • MF: C16H23NO5
  • MW: 309.358
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 461.5±45.0 °C at 760 mmHg
  • Melting Point: 110-117ºC
  • Flash Point: 232.9±28.7 °C

Ethyl 2-(2-(2-(4-chlorophenoxy)phenyl)-N-methylacetamido)acetate

Ethyl 2-(2-(2-(4-chlorophenoxy)phenyl)-N-methylacetamido)acetate is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 1035404-17-1
  • MF: C19H20ClNO4
  • MW: 361.81900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ALV2

ALV2 is a potent and selective Helios degrader. ALV2 binds CRBN, with an IC50 of 0.57 μM. Helios is the zinc-finger transcription factor that can maintain a stable Treg cell phenotype in the inflammatory tumor microenvironment[1].

  • CAS Number: 2438124-95-7
  • MF: C26H26ClN5O5
  • MW: 523.97
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fulvestrant 3-β-D-Glucuronide

Fulvestrant 3-β-D-Glucuronide, a metabolite, is glucuronide and sulfate conjugates of Fulvestrant (HY-13636), a pure anti-estrogenic steroid. Fulvestrant 3-β-D-Glucuronide can be used for the research of breast cancer[1].

  • CAS Number: 261506-27-8
  • MF: C38H55F5O9S
  • MW: 782.895
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 863.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 475.8±34.3 °C

Ethidium bromide

Ethidium bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.

  • CAS Number: 1239-45-8
  • MF: C21H20BrN3
  • MW: 394.308
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 260-262 °C (dec.)(lit.)
  • Flash Point: >100°C

Fmoc-D-Phg-OH

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-phenylacetic acid is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 111524-95-9
  • MF: C23H19NO4
  • MW: 373.401
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 606.3±50.0 °C at 760 mmHg
  • Melting Point: 176 °C(dec.)
  • Flash Point: 320.5±30.1 °C

Sodium formate-13C,d1

Sodium formate-13C,d1 is the deuterium and 13C labeled Sodium formate[1].

  • CAS Number: 1215684-17-5
  • MF: 13CHDNaO2
  • MW: 71.01
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

RCB16007

RCB16007 is a Yellow Fever Virus (YFV) Inhibitor. RCB16007 inhibits the West Nile virus (EC50: 7.9 μM, CC50: 17 μM)[1].

  • CAS Number: 2952530-26-4
  • MF: C18H14ClN5O2S
  • MW: 399.85
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ethane-1,2-diamine dihydrochloride-13C2

Ethane-1,2-diamine dihydrochloride-13C2 is the 13C labeled Ethane-1,2-diamine dihydrochloride[1].

  • CAS Number: 77435-60-0
  • MF: C2H10Cl2N2
  • MW: 135.00600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

chloroacetyl-dl-norleucine

N-Chloroacetyl-DL-norleucine is a leucine derivative[1].

  • CAS Number: 67206-26-2
  • MF: C8H14ClNO3
  • MW: 207.65500
  • Catalog: Others
  • Density: 1.2g/cm3
  • Boiling Point: 409.6ºC at 760 mmHg
  • Melting Point: 113ºC
  • Flash Point: 201.5ºC

Rotundatin

Rotundatin is useful in inhibition of the aggregation of platelets induced by arachidonic acid and collagen[1].

  • CAS Number: 144506-16-1
  • MF: C15H14O4
  • MW: 258.27
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

FMOC-D-4-Chlorophe

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-chlorophenyl)propanoic acid is a phenylalanine derivative[1].

  • CAS Number: 142994-19-2
  • MF: C24H20ClNO4
  • MW: 421.873
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 640.9±55.0 °C at 760 mmHg
  • Melting Point: 194ºC
  • Flash Point: 341.4±31.5 °C

Intermedine

(+)-Intermedine, a pyrrolizidine alkaloid (PA), exhibits significant cytotoxicity in neural progenitor cells (NPCs)[1].

  • CAS Number: 10285-06-0
  • MF: C15H25NO5
  • MW: 299.36300
  • Catalog: Neurological Disease
  • Density: 1.26g/cm3
  • Boiling Point: 463.3ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 234ºC

20(R)-Ginsenoside Rg3

20(R)-ginsenoside Rg3 (20(R)-Propanaxadiol), one of the active compounds present in ginseng root, has a potent angiosuppressive and antitumor activities[1][2].

  • CAS Number: 38243-03-7
  • MF: C42H72O13
  • MW: 1079.269
  • Catalog: Cancer
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 1117.1±65.0 °C at 760 mmHg
  • Melting Point: 315-318ºC
  • Flash Point: 629.4±34.3 °C

Wilforol A

Wilforol A ((-)-Wilforol A), plant metabolite, is a pentacyclic triterpenoid. Wilforol A can be used for the research of various biochemical studies[1].

  • CAS Number: 167882-66-8
  • MF: C29H38O5
  • MW: 466.609
  • Catalog: Metabolic Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 655.5±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 364.3±28.0 °C