Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Homoeriodictyol 7-O-glucoside

Homoeriodictyol 7-O-β-D-glucoside is a natural platelet-activating factor (PAF) antagonist. Homoeriodictyol 7-O-β-D-glucoside inhibits human and rabbit platelet aggregation induced by PAF, with an IC50 of 0.8 μM[1].

  • CAS Number: 14982-11-7
  • MF: C22H24O11
  • MW: 464.41900
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

MANNOTRIOSE-DI-(N-ACETYL-D-GLUCOSAMINE)

Paucimannose is a common mannosidic N-glycoepitope that exists in invertebrates and plants. paucimannosidic glycans are expressed in cancers[1].

  • CAS Number: 70858-45-6
  • MF: C34H58N2O26
  • MW: 910.82200
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ethyl 2-bromopropionate-d3

Ethyl 2-bromopropionate-d3 is the deuterium labeled Ethyl 2-bromopropionate[1].

  • CAS Number: 1398066-14-2
  • MF: C5H6D3BrO2
  • MW: 184.05
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

E-982

E-982 is extracted from the reference, compound 12.

  • CAS Number: 858102-78-0
  • MF: C25H31NO6S
  • MW: 473.582
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 666.7±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 357.0±34.3 °C

YMRF-NH2

YMRF-NH2 is a neuropeptide. YMRF-NH2 binds to FMRFa-R with an EC50 value of 31 nM[1][2].

  • CAS Number: 83903-32-6
  • MF: C29H42N8O5S
  • MW: 614.76
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Gentiournoside D

Gentiournoside D is a natural compound that can be found in G. asclepiadea extracts[1].

  • CAS Number: 157722-21-9
  • MF: C23H28O13
  • MW: 512.46
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 769.7±60.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-DON-Boc

Fmoc-DON-Boc (Compound 8b) is an Fmoc-protected compound that can be used for the synthesis of proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357). DON is a glutamine antagonist[1].

  • CAS Number: 1998724-98-3
  • MF: C24H25N3O5
  • MW: 435.47
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

EDANS

EDANS (1,5-EDANS) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET)[1].

  • CAS Number: 50402-56-7
  • MF: C12H14N2O3S
  • MW: 266.31600
  • Catalog: Others
  • Density: 1.432 g/cm3
  • Boiling Point: N/A
  • Melting Point: >350°C
  • Flash Point: N/A

Boc-D-glutamic acid α-benzylester

Boc-D-Glu-OBzl is a glutamic acid derivative[1].

  • CAS Number: 34404-30-3
  • MF: C17H23NO6
  • MW: 337.368
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 522.6±50.0 °C at 760 mmHg
  • Melting Point: 98 °C
  • Flash Point: 269.9±30.1 °C

N-Benzoyl-(2R,3S)-3-phenylisoserine

N-Benzoyl-(2R,3S)-3-phenylisoserine is a Taxol C-13 Side Chain and crucial for the strong antitumor activity of Taxol[1].

  • CAS Number: 132201-33-3
  • MF: C16H15NO4
  • MW: 285.29500
  • Catalog: Others
  • Density: 1.316g/cm3
  • Boiling Point: 580.7ºC at 760 mmHg
  • Melting Point: 169-172 °C(lit.)
  • Flash Point: 305ºC

γ-Tocotrienol-d6

γ-Tocotrienol-d6 is the deuterium labeled Fmoc-Met-OH[1].

  • CAS Number: 1174643-68-5
  • MF: C28H36D6O2
  • MW: 416.67
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cartilostatin 1

Cartilostatin 1 is an anti-angiogenic peptide. Cartilostatin 1 can be used for the research of anti-angiogenic[1].

  • CAS Number: 929555-05-5
  • MF: C86H142N30O29S2
  • MW: 2124.36
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tris(benzyltriazolylmethyl)amine

Tris(benzyltriazolylmethyl)amine (TBTA) is a ligand that acts as a biochemical tool for the tagging of proteins and enzymes[1].

  • CAS Number: 510758-28-8
  • MF: C30H30N10
  • MW: 530.626
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 762.4±70.0 °C at 760 mmHg
  • Melting Point: 132-143℃
  • Flash Point: 414.9±35.7 °C

Dodecyltrimethylammonium-d34(bromide)

Dodecyltrimethylammonium-d34 (bromide) is the deuterium labeled Dodecyltrimethylammonium (bromide)[1]. Dodecyltrimethylammonium bromide (DTAB) is a surfactant. Dodecyltrimethylammonium bromide interacts with DNA and changes the mechanical properties of DNA on binding and the specific binding parameters of the interaction[2].

  • CAS Number: 2259752-12-8
  • MF: C15D34BrN
  • MW: 342.55
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Nitrobenzonitrile-d4

4-Nitrobenzonitrile-d4 is the deuterium labeled NSC 88911[1].

  • CAS Number: 1219798-46-5
  • MF: C7D4N2O2
  • MW: 152.14
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 307.7±25.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 139.9±23.2 °C

neocaesalpin AH

2-Acetoxy-3-deacetoxycaesaldekarin e (compound 11) is a furanoditerpene that can be found in Caesalpinia crista[1].

  • CAS Number: 18326-06-2
  • MF: C24H30O6
  • MW: 414.49
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 498.7±45.0 °C at 760 mmHg
  • Melting Point: 191-192℃
  • Flash Point: 255.4±28.7 °C

2'-Hydroxylisoagarotetrol

2'-Hydroxylisoagarotetrol is a natural product[1].

  • CAS Number: 104926-77-4
  • MF: C17H18O7
  • MW: 334.32
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

insulin lispro (5.97 mg)

Insulin lispro is a recombinant human insulin analogue and is one of three rapid-acting insulin analogues available. Insulin lispro can be used for the research of hyperglycaemia in diabetes mellitus[1].

  • CAS Number: 133107-64-9
  • MF: C257H389N65O77S6
  • MW: 5807.57022
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

WAY-604439

WAY-604439 is an active molecule.

  • CAS Number: 521281-98-1
  • MF: C20H14ClFN4S
  • MW: 396.87
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

β-Phenyl-L-phenylalanin

(S)-2-Amino-3,3-diphenylpropanoic acid is an alanine derivative[1].

  • CAS Number: 149597-92-2
  • MF: C15H15NO2
  • MW: 241.285
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 389.2±30.0 °C at 760 mmHg
  • Melting Point: 210-213ºC
  • Flash Point: 189.2±24.6 °C

MGH-CP1

MGH-CP1 is a potent and orally active TEAD2 and TEAD4 auto-palmitoylation inhibitor with IC50s of 710 nM and 672 nM, respectively. MGH-CP1 can decrease the palmitoylation levels of endogenous or ectopically expressed TEAD proteins in cells. MGH-CP1 can suppress Myc expression, inhibit epithelial over-proliferation, and induce apoptosis when together with Lats1/2 deletion[1].

  • CAS Number: 896657-58-2
  • MF: C20H24N4OS
  • MW: 368.50
  • Catalog: Apoptosis
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Isometronidazole-d4 hydrochloride

Isometronidazole-d4 hydrochloride is the deuterium labeled Isometronidazole[1].

  • CAS Number: 2748356-10-5
  • MF: C6H6D4ClN3O3
  • MW: 211.64
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Palmitoyl Hexapeptide-14

Palmitoyl hexapeptide-14(Palmitoyl hexapeptide-6)isa bioactive peptide withanti-inflammatoryeffect and has been reported used as a cosmetic ingredient[1].

  • CAS Number: 891498-01-4
  • MF: C52H92N8O7
  • MW: 941.336
  • Catalog: Metabolic Disease
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 1148.7±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 648.5±34.3 °C

L-4-Nitrophenylalanine methyl ester hydrochloride

4-Nitro-L-phenylalanine methyl ester hydrochloride is a phenylalanine derivative[1].

  • CAS Number: 17193-40-7
  • MF: C10H13ClN2O4
  • MW: 260.674
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 360ºC at 760 mmHg
  • Melting Point: 210-214 °C
  • Flash Point: 171.5ºC

Alpha-Terpineol

(-)-α-Terpineol ((S)-α-Terpineol), a monoterpene compound, is one of important aroma compounds in white wines[1].

  • CAS Number: 10482-56-1
  • MF: C10H18O
  • MW: 154.249
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 217.5±0.0 °C at 760 mmHg
  • Melting Point: 31-35ºC
  • Flash Point: 89.4±0.0 °C

Idactamab

Idactamab (INT-001) is an IgG1-κ antibody with in vivo activity across a spectrum of hematological malignancies. Idactamab can be used for prepare MEDI7247, a potent and specific ADC, targeting ASCT2 (SLC1A5)[1][2].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-azidophlorhizin

4-Azidophlorizin is a high affinity probe and photoaffinity label for the glucose transporter in brush border membranes[1].

  • CAS Number: 79541-46-1
  • MF: C21H23N3O9
  • MW: 461.42202
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 168-170°C dec.
  • Flash Point: N/A

N-Methylcoclaurine

(-)-N-methylcoclaurine possesses melanogenesis inhibitory activity[1].

  • CAS Number: 5096-70-8
  • MF: C18H21NO3
  • MW: 299.364
  • Catalog: Metabolic Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 480.9±45.0 °C at 760 mmHg
  • Melting Point: 184-185℃
  • Flash Point: 244.6±28.7 °C

Benzenesulfonamide, 5-[[5-fluoro-4-[[4-(2-propyn-1-yloxy)phenyl]amino]-2-pyrimidinyl]amino]-2-methyl-

Benzenesulfonamide is a useful composition for treating and/or preventing dry eye disorders.

  • CAS Number: 916741-98-5
  • MF: C20H18FN5O3S
  • MW: 427.45
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SPL-410

SPL-410 is an orally active, highly potent and selective hydroxyethylamine based SPPL2a (Signal Peptide Peptidase Like 2a) inhibitor, with an IC50 of 9 nM[1].

  • CAS Number: 2351886-00-3
  • MF: C24H31F3N2O4S
  • MW: 500.57
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A