Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Hyocholic Acid

Hyocholic Acid is a bile acid found in pig. Hyocholic Acid can also be found in urine samples from patients with cholestasis. Hyocholic Acid promotes GLP-1 secretion via activating TGR5 and inhibiting FXR in enteroendocrine cells. Hyocholic Acid is known for its exceptional resistance to type 2 diabetes [1][2][3].

  • CAS Number: 547-75-1
  • MF: C24H40O5
  • MW: 408.571
  • Catalog: Metabolic Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 565.7±40.0 °C at 760 mmHg
  • Melting Point: 188-189ºC
  • Flash Point: 310.0±23.8 °C

2-(Trifluoromethyl)-D-phenylalanine

(R)-2-Amino-3-(2-(trifluoromethyl)phenyl)propanoic acid is a phenylalanine derivative[1].

  • CAS Number: 130930-49-3
  • MF: C10H10F3NO2
  • MW: 233.187
  • Catalog: Others
  • Density: 1.364 g/cm3
  • Boiling Point: 299.4±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 134.9±27.3 °C

L-Methionine-d3-methyl-d3-sulfonium chloride HCl-d6 hydrochloride

L-Methionine-d3-methyl-d3-sulfonium chloride HCl-d6 (hydrochloride) is the deuterium labeled L-Methionine-methyl-sulfonium chloride HCl hydrochloride[1].

  • CAS Number: 63889-27-0
  • MF: C6H15ClNO2S2
  • MW: 232.77200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Vernolide B

Vernolide-B has cytoxicity (ED50s: 3.78, 5.88, 6.42 μg/mL for KB, NCI-661, and HeLa cells respectively). Vernolide B is sesquiterpene lactone that can be isolated from Vernonia cinerea[1].

  • CAS Number: 618860-58-5
  • MF: C23H30O8
  • MW: 434.48
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 568.4±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 244.6±30.2 °C

Dihydrojasmone

Dihydrojasmone, compound 4, constituent of bergamot oil, is an important perfume ingredient[1].

  • CAS Number: 1128-08-1
  • MF: C11H18O
  • MW: 166.26000
  • Catalog: Others
  • Density: 0.916 g/mL at 25 °C(lit.)
  • Boiling Point: 120-121 °C12 mm Hg(lit.)
  • Melting Point: N/A
  • Flash Point: 230 °F

Lupeol caffeate

Caffeoxylupeol is a natural compound with anticancer activity that can be isolated from the Leaves of Dalbergia velutina[1].

  • CAS Number: 103917-26-6
  • MF: C39H56O4
  • MW: 588.86
  • Catalog: Cancer
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 654.4±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 192.8±22.2 °C

Implitapide

Implitapide (AEGR 427) is a microsomal triglyceride transfer protein (MTP) inhibitor.

  • CAS Number: 177469-96-4
  • MF: C35H37N3O2
  • MW: 531.687
  • Catalog: Cardiovascular Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 739.3±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 400.9±32.9 °C

Bromoiodoacetamide

Bromoiodoacetamide is a kind of iodinated haloacetamides (I-HAcAms), with cytotoxicity. Bromoiodoacetamide induces cytotoxicity by via reactive oxygen species (ROS) accumulation and apoptosis in HepG-2 cells[1].

  • CAS Number: 62872-36-0
  • MF: C2H3BrINO
  • MW: 263.86000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Eupatolin

Eupatolin is a nature product that could be isolated from Rudbeckia hirta[1].

  • CAS Number: 29725-50-6
  • MF: C23H24O12
  • MW: 492.42900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Verzistobart

Verzistobart is an IgG1κ antibody targeting the hepatitis A virus cellular receptor HAVCR2.

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Inosine-15N4

Inosine-15N4 is the 15N labeled Inosine[1].

  • CAS Number: 204634-01-5
  • MF: C10H1215N4O5
  • MW: 272.20
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Pyanchor

Pyribenzoxim (LGC-40863) is a broad-spectrum herbicide. Pyribenzoxim has a higher safety level in bentgrass and a stronger herbicidal activity on grass weeds[1].

  • CAS Number: 168088-61-7
  • MF: C32H27N5O8
  • MW: 609.586
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 810.8±75.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 444.1±37.1 °C

H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride

H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride, a norbornene-derivatized lysine, can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride can be used for the mild and selective modification of proteins in a copper-free click reaction[1].

  • CAS Number: 2560614-20-0
  • MF: C15H25ClN2O4
  • MW: 332.82
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Biotin-XX hydrazide

Biotin-XX hydrazide (Biotin-(AC5)2-hydrazide) is a carbonyl-reactive biotinylation reagent which contains two aminohexanoic acid spacers. Biotin-XX hydrazide has higher efficiency of avidin-binding[1].

  • CAS Number: 211237-33-1
  • MF: C22H40N6O4S
  • MW: 484.656
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 904.8±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 501.0±34.3 °C

Zuclomiphene-d5 citrate

Zuclomiphene-d5 (citrate) is the deuterium labeled Zuclomiphene citrate[1]. Zuclomiphene citrate is a cis isomer of Clomiphene citrate. Zuclomiphene citrate has an antiestrogenic effect and can inhibit the secretion of luteinizing hormone (LH) more than the trans isomer. Zuclomiphene citrate is also an orally active hypocholesterolemic agent[2][3][4][5].

  • CAS Number: 1795132-80-7
  • MF: C32H31D5ClNO8
  • MW: 603.11
  • Catalog: Estrogen Receptor/ERR
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

8-(2-AMINOETHYLAMINO)-1-NAPHTHALENESULFONIC ACID

N-(Aminoethyl)-8-naphthylamine-1-sulfonic acid is a fluorescent reagent[1].

  • CAS Number: 50402-57-8
  • MF: C12H14N2O3S
  • MW: 266.31600
  • Catalog: Others
  • Density: 1.432g/cm3
  • Boiling Point: N/A
  • Melting Point: 345-350ºC dec.
  • Flash Point: N/A

H-Leu-Ser-Pro-Phe-Pro-Phe-Asp-Leu-OH trifluoroacetate salt

p2Ca, an 8-mer peptide, is a ligand that is naturally processed and presented to the Ld-alloreactive T cell clone, 2C.

  • CAS Number: 142606-55-1
  • MF: C47H66N8O12
  • MW: 935.07300
  • Catalog: Peptides
  • Density: 1.298g/cm3
  • Boiling Point: 1307.2ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 744.4ºC
  • CAS Number: 352276-62-1
  • MF: C12H24N4O6
  • MW: 320.34200
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Lasiodin

Lasiokaurin is a diterpenoid compound isolated from Isodon lasiocarpus[1].

  • CAS Number: 28957-08-6
  • MF: C22H30O7
  • MW: 406.47
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 588.0±50.0 °C at 760 mmHg
  • Melting Point: 238-239℃
  • Flash Point: 203.8±23.6 °C

BODIPY 665/676

BODIPY 665/676 is a lipophilic radical-sensitive fluorescent probe that can be used to study radical-driven lipid autoxidation[1].

  • CAS Number: 164106-16-5
  • MF: C29H23BF2N2
  • MW: 448.31
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PW0787

PW0787 is a potent, selective, orally active, and brain-penetrant GPR52 agonist (EC50=135 nM). PW0787 suppresses psychostimulant behavior[1].

  • CAS Number: 2624131-45-7
  • MF: C23H20F4N4O2
  • MW: 460.42
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hederagenin-28-beta-D-glucopyranoside

Hederagenin 28-O-beta-D-glucopyranosyl ester, a triterpenoid saponin isolated from Ilex cornuta, exhibits protective effects against H2O2-induced myocardial cell injury[1].

  • CAS Number: 53931-25-2
  • MF: C36H58O9
  • MW: 634.840
  • Catalog: Cardiovascular Disease
  • Density: 1.27±0.1 g/cm3
  • Boiling Point: 729.7±60.0 °C at 760 mmHg
  • Melting Point: 197-202 ºC (methanol )
  • Flash Point: 220.2±26.4 °C

Proinsulin C-Peptide (55-89) human

Proinsulin C-Peptide (55-89), human is a peptide fragment of the cleavage product of proinsulin[1].

  • CAS Number: 11097-48-6
  • MF: C153H259N49O52
  • MW: 3616.99000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sodium 2-oxo-2-phenylacetate

Phenylglyoxylic acid (sodium) is the sodium salt form of Phenylglyoxylic acid. Phenylglyoxylic acid as a biomarker of exposure to ethylbenzene and styrene (EB/S)[1].

  • CAS Number: 43165-51-1
  • MF: C8H5NaO3
  • MW: 172.11
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 258.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 124.4ºC

Isocostic acid

γ-Costic acid (compound 13)is a kind of terpenoid. γ-Costic acid can be obtained by chemical transformation. γ-Costic acid has effective antifeedant and cytotoxic doses with EC50 0.5 μg/ml against L. decemlineata[1].

  • CAS Number: 69978-82-1
  • MF: C15H22O2
  • MW: 234.33
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 374.0±11.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 273.7±10.2 °C

4-[4,7-Bis(2-tert-butoxy-2-oxoethyl)-1,4,7-triazonan-1-yl]-5-tert-butoxy-5-oxopentanoicAcid

NODAGA-tris(t-Bu ester) (NODAG) is a NODAGA derivative. NODAGA-tris(t-Bu ester) can be used to label peptides, antibodies, etc., and subsequently radiolabeled for PET imaging[1].

  • CAS Number: 1190101-34-8
  • MF: C27H49N3O8
  • MW: 543.69
  • Catalog: Cancer
  • Density: 1.095±0.06 g/cm3(Predicted)
  • Boiling Point: 608.1±55.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

Oxyfenamate

Oxyfenamate has anti-anxiety actions for use in anxiety neuroses.

  • CAS Number: 50-19-1
  • MF: C11H15NO3
  • MW: 209.24200
  • Catalog: Neurological Disease
  • Density: 1.18g/cm3
  • Boiling Point: 415.4ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 205.1ºC

DiSBAC2(5)

DiBAC4(3) is a voltage-sensitive fluorescent dye (λex=490 nm, λem=505 nm).

  • CAS Number: 70363-83-6
  • MF: C27H40N4O6
  • MW: 516.63
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DIM-C-pPhCO2Me

DIM-C-pPhCO2Me is a nuclear receptor 4A1 (NR4A1) antagonist[1]. Antineoplastic activity[1].

  • CAS Number: 151358-48-4
  • MF: C25H20N2O2
  • MW: 380.44
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-CPs

3-CPs is a serotype capsular polysaccharide which can interfere with antibody-mediated bacterial killing.

  • CAS Number: 20073-24-9
  • MF: C14H10O5
  • MW: 258.22600
  • Catalog: Infection
  • Density: 1.387g/cm3
  • Boiling Point: 437.3ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 218.3ºC