TAT-amide is a cell penetrating peptide. Cell-penetrating peptides (CPPs) are short amino acid sequences able to enter different cells[1][2].
Trofinetide, a synthetic analogue of the endogenous N-terminus tripeptide, Glycine-Proline-Glutamate (GPE), has been shown to be neuroprotective in animal models of brain injury.
INH6 is a potent Nek2/Hec1 inhibitor; inhibits the growth of HeLa cells with an IC50 of 2.4 μM.
Boc-Glu(OBzl)-OSu can be used for the solid-phase peptide synthesis containing glutamate benzyl ester residues.
1-Bromooctane-1,1-d2 is the deuterium labeled 1-Bromooctane[1].
10-(3-Sulfopropyl)acridinium Betaine is a fluorescent dye with high durability (>3 months)[1].
Protoescigenin is the main aglycone of horse chestnut saponin mixture known as escin. Protoescigenin is selected as substrate for exploratory chemistry towards selective protection, followed by propargyl ether formation and subsequent condensation with azido-monosaccharides, to obtain novel triazole linked conjugates of the triterpene[1].
4'-Demethyldehydropodophyllotoxin is an aryltetralin lignan that can be isolated from leaves of Podophyllum hexandrum. 4'-Demethyldehydropodophyllotoxin exhibits some cytotoxic and antitumour activity[1].
Fmoc-Lys-OAll.HCl is a lysine derivative[1].
(S)-N-Methyl-N-methoxy-2-(tert-butoxycarbonylamino)-4-methylpentanamide is a leucine derivative[1].
Ds-HAPP is an anthrancenyl and dansyl fluorophore ligand.
Fentiazac, alkanoic acid derivative, is an orally active non-steroidal anti-inflammatory agent, with analgesic, antipyretic and platelet anti-aggregation activity. Fentiazac can be used to research inflammatory diseases such as rheumatoid arthritis, osteoarthritis and tendinitis[1][2][3].
GDC-0927 (SRN-927, RG-6047) is a potent, orally bioavailable, selective estrogen receptor degrader (SERD) for treatment of metastatic hormone receptor-positive/HER2-negative breast cancer.
9-Nitroanthracene-d9 is the deuterium labeled 9-Nitroanthracene[1].
Denatonium is the most bitter chemical compound known,used as aversive agents (bitterants) to prevent inappropriate ingestion. Denatonium is used in denatured alcohol, antifreeze, nail biting preventions, respirator mask fit-testing, animal repellents, liquid soaps, and shampoos.
Glycine tert-butyl ester dibenzenesulfonimide salt is a Glycine (HY-Y0966) derivative[1].
8,8''-Bibaicalein is a natural product that can be found in baicalensis[1].
7beta-Hydroxylathyrol is a natural product.
Antiproliferative agent-41 (compound 14) is a antiproliferative agent indanorine[1].
HPA-12 is an intracellular ceramide transport protein inhibitor[1].
Exherin trifluoroacetate is an N-cadherin antagonist, which inhibits N-cadherin mediated cell adhesion.
Glimepiride-d4(phenylethyl-α,α,β,β-d4)(cis/trans) is the deuterium labeled [1].
PolQi2 inhibits the helicase activity of Polθ. PolQi2 improves the precision of gene editing at various loci and in different cell lines[1].
Dodecanal is composition of essential oil that can be found in Coriandrum sativum L.[1]
CP 154526, a non peptidic corticotropin releasing factor receptor antagonist attenuates fever and exhibits anxiolytic-like activity[1].
Estradiol dipropionate is a combined estrogen-progesterone, acts as an estrogen and progesterone agonist[1].
Pipebuzone (LD 4644) is an anti-inflammatory, antipyretic and analgesic agent. Pipebuzone plays an important raol in rheumatic diseases[1].
Clinopodiside A, a triterpenoid saponin, is isolated from Clinopodium polycephalum which is a popular Chinese traditional medicinal herb[1][2].
Pterodondiol is a gandular trichome metabolite on the leaves of Laggera pterodonta[1].
APJ receptor agonist 5 (compound 3) is a potent and orally active agonist of apelin receptor (APJ) with an EC50 of 0.4 nM. APJ receptor agonist 5 displays excellent pharmacokinetic profiles in the rodent heart failure (HF) model. APJ receptor agonist 5 also shows an acceptable safety profile in preclinical toxicology studies. APJ receptor agonist 5 leads to improved cardiac function and can be used for researching the HF disease[1].