Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

H-Arg-His-NH2 acetate salt

Arg-His-NH2 is a biologically active peptide.

  • CAS Number: 244765-93-3
  • MF: C12H22N8O2
  • MW: 310.355
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(2R,3R,4aR)-2,3,4,4a-Tetrahydro-2,3,7-trihydroxy-9-Methoxy-4a-Methyl-6H-dibenzo[b,d]pyran-6-one

(-)-Altenuene is a heptaketide isolated from an endolichenic fungal strain Nigrospora sphaerica[1].

  • CAS Number: 889101-41-1
  • MF: C15H16O6
  • MW: 292.284
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 609.4±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 233.5±25.0 °C

NorA-IN-1

NorA-IN-1 (Compound 16) is a NorA inhibitor. NorA-IN-1 inhibits NorA efflux pump in everted membrane vesicles. NorA-IN-1 can be used for research of multidrug resistance[1].

  • CAS Number: 1389310-69-3
  • MF: C18H18O5
  • MW: 314.33
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Coumarin 314

Coumarin 314 is a dye which has an intense absorption in the visible and additionally presents a large solvent dependence[1].

  • CAS Number: 55804-66-5
  • MF: C18H19NO4
  • MW: 313.348
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 542.5±50.0 °C at 760 mmHg
  • Melting Point: 140-144ºC
  • Flash Point: 281.9±30.1 °C

1α-Hydroxytorilin

1 α-hydroxytorilin (compound 3) is a sesquiterpenoid. 1 α-hydroxytorilin can be isolated from Torilis japonica. 1α-hydroxytorilin has cytotoxicity against human A549, SK-OV-3, SK-MEL-2, and HCT15 tumor cells with ED50 values of 20.52, 18.24, 17.48, 42.54 μg/mL, respectively[1].

  • CAS Number: 887147-75-3
  • MF: C22H32O6
  • MW: 392.486
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 502.5±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 165.3±23.6 °C

Stigmasta-5,25-dien-3-ol,(3b,24S)-

(-)-Clerosterol is a natural product that can be isolated from Codium fragile[1].

  • CAS Number: 2364-23-0
  • MF: C29H48O
  • MW: 412.69
  • Catalog: Others
  • Density: 0.98g/cm3
  • Boiling Point: 502.7ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 219.8ºC

6a-Hydroxymedicarpin

6a-Hydroxymedicarpin is a monoterpenoid indole alkaloid that can be isolated from Ochrosia elliptica. 6a-Hydroxymedicarpin has anticancer activity[1].

  • CAS Number: 61135-92-0
  • MF: C16H14O5
  • MW: 286.28
  • Catalog: Cancer
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 487.0±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 248.3±28.7 °C

BLXA-4

BLXA-4 is used potentially to treat gingival diseases.

  • CAS Number: 362516-29-8
  • MF: C23H34O5
  • MW: 390.51
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-3 (1 naphthyl)-L alanine; Fmoc-1-Nal-OH

Fmoc-D-1-Nal-OH is an alanine derivative[1].

  • CAS Number: 138774-93-3
  • MF: C28H23NO4
  • MW: 437.487
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 690.7±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 371.6±30.1 °C

Selina-4(15),7(11)-dien-8-one

Selina-4(14),7(11)-dien-8-one is a sesquiterpene that can be isolated from Atractylodes Macrocephala Rhizoma [1].

  • CAS Number: 54707-47-0
  • MF: C15H22O
  • MW: 218.33
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bz-Tyr-4-Abz-OH

Bentiromide is a peptide that is broken down in the pancreas by chymotrypsin. The bentiromide test is an excellent means of confirming the diagnosis of pancreatic exocrine insufficiency by outpatient test of chymotrypsin function[1].

  • CAS Number: 37106-97-1
  • MF: C23H20N2O5
  • MW: 404.41500
  • Catalog: Others
  • Density: 1.367g/cm3
  • Boiling Point: 797.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 435.9ºC

RhoNox-1

RhoNox-1 is a fluorescent dye. RhoNox-1 shows a high selection of Fe(II) ions that can be used as fluorescent probes for specific label labile ferrous iron [Fe(II)]. RhoNox-1 can be used to identify the level of the intracellular labile iron pool[1][2][3].

  • CAS Number: 1447815-38-4
  • MF: C28H31N2O4+
  • MW: 459.56
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sodium phosphate monobasic monohydrate

Sodium phosphate monobasic monohydrate is a commonly used buffer[1].

  • CAS Number: 10049-21-5
  • MF: H4NaO5P
  • MW: 137.992
  • Catalog: Others
  • Density: 2.04 g/cm3
  • Boiling Point: 158ºC at 760mmHg
  • Melting Point: 60℃
  • Flash Point: N/A

Atrial Natriuretic Peptide (7-28), human, canine

Atrial Natriuretic Peptide (7-28), human, canine is a peptide fragment of atrial natriuretic peptide, can be used as a peptide tag[1].

  • CAS Number: 128746-58-7
  • MF: C100H155N33O30S3
  • MW: 2395.70
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cimicifugoside H1

Cimicifugoside H-1, a cyclolanostanol xyloside, is a major constituent of C. foetida L. extract. Cimicifugoside H-1 inhibits bone resorption and ovariectomy-induced bone loss[1][2][3].

  • CAS Number: 163046-73-9
  • MF: C37H54O11
  • MW: 674.81800
  • Catalog: Metabolic Disease
  • Density: 1.31±0.1 g/cm3 at 760 mmHg
  • Boiling Point: 748.9±60.0 °C at 760 mmHg
  • Melting Point: 260-262 °C
  • Flash Point: N/A

12-Hydroxyganoderic acid D

12-Hydroxyganoderic Acid D is a triterpenoid extracted from Ganoderma lucidum[1].

  • CAS Number: 942950-96-1
  • MF: C30H42O8
  • MW: 530.650
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 722.4±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 404.6±29.4 °C

Retronecine

Retronecine ((+)-Retronecine) is a pyrrolizidine alkaloid found in a variety of plants. Retronecine is the most common central core for other pyrrolizidine alkaloids[1].

  • CAS Number: 480-85-3
  • MF: C8H13NO2
  • MW: 155.19400
  • Catalog: Others
  • Density: 1.29g/cm3
  • Boiling Point: 291.3ºC at 760mmHg
  • Melting Point: 119-120°
  • Flash Point: 161.4ºC

Microsomal aminopeptidase

Microsomal aminopeptidase (microsomal aminoptidase) was first reported from C. elegans. The Microsomal aminopeptidase is beneficial for the development of molecular vaccines against parasitic nematodes[1].

  • CAS Number: 9054-63-1
  • MF: C12H24O2
  • MW: 200.31776
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Benzimidazolethiol-d4

2-Benzimidazolethiol-d4 is the deuterium labeled 2-Benzimidazolethiol[1].

  • CAS Number: 931581-17-8
  • MF: C7H2D4N2S
  • MW: 154.22600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Ethylcaprylic acid

4-Ethyloctanoic acid is a natural compound first isolated from Saussurea lappa Clarke, widely used as a safe flavoring compound and acts as food additive[1].

  • CAS Number: 16493-80-4
  • MF: C10H20O2
  • MW: 172.265
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 271.6±8.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 142.3±6.9 °C

Retinyl glucoside

Retinyl-β-D-glucoside is a naturally occurring and biologically active metabolites of vitamin A, which are found in fish and mammals.IC50 Value: Target: in vitro: Retinyl beta-D-glucoside is a substrate for two broad-specificity mammalian beta-glucosidases, namely the cytosolic and membrane-associated beta-glucosidases of guinea pig liver. However, retinyl beta-D-glucoside is not hydrolysed by placental glucocerebrosidase [1].in vivo: Depending on the mode of administration, retinyl beta-glucose, which is soluble in water, showed 67-100% of the growth-promoting activity of retinyl acetate in vitamin A-deficient rats. In metabolic studies on vitamin A-deficient rats, retinyl beta-glucose was rapidly hydrolyzed to retinol [2].

  • CAS Number: 136778-12-6
  • MF: C26H40O6
  • MW: 448.59
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

L-Gulose

L-Gulose, the putative furanose form of L-sorbosone, is an L-hexose sugar and an intermediate in the biosynthesis of L-Ascorbate (vitamin C)[1].

  • CAS Number: 6027-89-0
  • MF: C6H12O6
  • MW: 180.156
  • Catalog: Metabolic Disease
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 410.8±45.0 °C at 760 mmHg
  • Melting Point: 132ºC
  • Flash Point: 202.2±28.7 °C

holo-transferrin

Transferrin, a blood-plasma glycoprotein, is a target ligand for transferrin receptor. Transferrins can bind to and mediate the transport of iron[1][2][3].

  • CAS Number: 11096-37-0
  • MF: C16H22N6O4
  • MW: 362.38368
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-L-Photo-Lysine

Fmoc-L-Photo-Lysine is a lysine derivative[1].

  • CAS Number: 2250437-42-2
  • MF: C26H30N4O6
  • MW: 494.54
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

magnesium aspartate dihydrate

Magnesium L-aspartate dihydrate is an aspartic acid derivative[1].

  • CAS Number: 215533-00-9
  • MF: C8H16MgN2O10
  • MW: 324.525
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Glycine, N-[(3-methoxyphenyl)methyl]- (9CI)

N-(3-Methoxybenzyl)glycine is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 756754-04-8
  • MF: C10H13NO3
  • MW: 195.21500
  • Catalog: Others
  • Density: 1.174g/cm3
  • Boiling Point: 351.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 166.4ºC

boc-asp(oall)-oh

Boc-Asp(OAll)-OH is an aspartic acid derivative[1].

  • CAS Number: 132286-77-2
  • MF: C12H19NO6
  • MW: 273.28200
  • Catalog: Others
  • Density: 1.175g/cm3
  • Boiling Point: 437.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 218.4ºC

11α,12α-Epoxy-3β,23-dihydroxy-30-norolean-20(29)-en-28,13β-olide

11α,12α-Epoxy-3β,23-dihydroxy-30-norolean-20(29)-en-28 is a triterpenoid that isolated from Paeonia Lactiflora[1].

  • CAS Number: 186140-36-3
  • MF: C29H42O5
  • MW: 470.641
  • Catalog: Cardiovascular Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 621.5±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 202.9±25.0 °C

inosine 5'-(trihydrogen diphosphate)

Riboxin (IDP), an orally active purine derivative-hypoxanthine rlboside, has antihypoxic and antihyperthermic activity. Riboxin also has an antiarrhythmic action in cats, rabbits, and mice with cardiac rhythm disorders induced by Ouabain. Riboxin protects animals against the noxious effects of γ-irradiation[1][2].

  • CAS Number: 86-04-4
  • MF: C10H13N4O15P3--
  • MW: 522.14900
  • Catalog: Cardiovascular Disease
  • Density: 2.49g/cm3
  • Boiling Point: 925.2ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 513.3ºC

(4-Nitrophenyl)(phenyl)methanone-d5

(4-Nitrophenyl)(phenyl)methanone-d5 is the deuterium labeled (4-Nitrophenyl)(phenyl)methanone[1].

  • CAS Number: 93496-61-8
  • MF: C13H4D5NO3
  • MW: 232.25
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A