inosine 5'-(trihydrogen diphosphate)

Modify Date: 2024-01-03 18:37:21

inosine 5'-(trihydrogen diphosphate) structure	Common Name	inosine 5'-(trihydrogen diphosphate)
	CAS Number	86-04-4	Molecular Weight	522.14900
	Density	2.49g/cm3	Boiling Point	925.2ºC at 760 mmHg
	Molecular Formula	C₁₀H₁₃N₄O₁₅P₃--	Melting Point	N/A
	MSDS	N/A	Flash Point	513.3ºC

Use of inosine 5'-(trihydrogen diphosphate)

Riboxin (IDP), an orally active purine derivative-hypoxanthine rlboside, has antihypoxic and antihyperthermic activity. Riboxin also has an antiarrhythmic action in cats, rabbits, and mice with cardiac rhythm disorders induced by Ouabain. Riboxin protects animals against the noxious effects of γ-irradiation[1][2].

Name	idp
Synonym	More Synonyms

Description	Riboxin (IDP), an orally active purine derivative-hypoxanthine rlboside, has antihypoxic and antihyperthermic activity. Riboxin also has an antiarrhythmic action in cats, rabbits, and mice with cardiac rhythm disorders induced by Ouabain. Riboxin protects animals against the noxious effects of γ-irradiation[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vivo	Riboxin (250 mg/kg; 口服; 单剂量) 可增加小鼠的游泳时间，但对力量耐力无显著影响。在相同条件下，Riboxin 提高了热室实验中动物的存活率[1]。 Riboxin (50 mg/kg; 口服; 每天1次，持续6天) 增加小鼠游走的时间，而对游泳和跑步的时间无显著影响[1]。 Riboxin (250 mg/kg; 口服; 实验前 1 小时) 对小鼠有明显的 γ 辐照保护作用[1]。
References	[1]. Sokolov I K, et al. Adaptogenic effect of riboxin[J]. Pharmaceutical Chemistry Journal, 1980, 14(1): 34-39. [2]. Veveris M, et al. Experimental study of the antiarrhythmic effect of riboxin. Farmakol. Neirotropnykh Sredstv (1978), 119-24.

Density	2.49g/cm3
Boiling Point	925.2ºC at 760 mmHg
Molecular Formula	C₁₀H₁₃N₄O₁₅P₃--
Molecular Weight	522.14900
Flash Point	513.3ºC
Exact Mass	521.95900
PSA	328.66000
Index of Refraction	1.883

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NM7515000

CHEMICAL NAME :: Inosine 5'-(trihydrogen pyrophosphate)

CAS REGISTRY NUMBER :: 86-04-4

LAST UPDATED :: 199707

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H14-N4-O11-P2

MOLECULAR WEIGHT :: 428.22

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3790 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 51,100,1988

O5'-trihydroxydiphosphoryl-inosine

riboxine

Inosindiphosphat

Inosine 5'-pyrophosphate

Inosin-5'-diphosphat

[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)oxolan-2-yl]methyl phosphono hydrogen phosphate

Inosine diphosphate

Inosine 5'-diphosphate

5'-inosine diphosphate

Riboxin

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China
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China
Product Name: inosine 5'-(trihydrogen diphosphate)
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Purity: 98.0%
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Use of inosine 5'-(trihydrogen diphosphate)

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