1447815-38-4

1447815-38-4 structure

Name: RhoNox-1
Chemical Name: RhoNox-1
CAS Number: 1447815-38-4
Molecular Formula: C₂₈H₃₁N₂O₄+
Molecular Weight: 459.56
Catalog: Research Areas Others
Create Date: 2022-10-11 11:22:30
Modify Date: 2024-01-31 18:41:59
RhoNox-1 is a fluorescent dye. RhoNox-1 shows a high selection of Fe(II) ions that can be used as fluorescent probes for specific label labile ferrous iron [Fe(II)]. RhoNox-1 can be used to identify the level of the intracellular labile iron pool[1][2][3].

Name	RhoNox-1

Description	RhoNox-1 is a fluorescent dye. RhoNox-1 shows a high selection of Fe(II) ions that can be used as fluorescent probes for specific label labile ferrous iron [Fe(II)]. RhoNox-1 can be used to identify the level of the intracellular labile iron pool[1][2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	RhoNox-1 signal colocalized with the generation of hydroxyl radicals, as detected by hydroxyphenyl fluorescein (HPF)[1]. RhoNox-1 (5 µM; 1h) can be used to strain LIP (labile iron pool) in MMNK1, KKU-213, and KKU-214 cells[2]. RhoNox-1 (10 µM; 1h) can be used to analyze iron metabolism in OVA-induced allergic peritonitis rats cells[3].
References	[1]. Mukaide T, et al. Histological detection of catalytic ferrous iron with the selective turn-on fluorescent probe RhoNox-1 in a Fenton reaction-based rat renal carcinogenesis model. Free Radic Res. 2014 Sep;48(9):990-5. [2]. Jamnongkan W, et al. Upregulation of transferrin receptor-1 induces cholangiocarcinoma progression via induction of labile iron pool. Tumour Biol. 2017 Jul;39(7):1010428317717655. [3]. Ito F, et al. Contrasting intra- and extracellular distribution of catalytic ferrous iron in ovalbumin-induced peritonitis. Biochem Biophys Res Commun. 2016 Aug 5;476(4):600-606.

Molecular Formula	C₂₈H₃₁N₂O₄+
Molecular Weight	459.56