Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

TMPD dihydrochloride

TMPD dihydrochloride, a readily oxidizable compound, is an enzymatically convert redox active substrate molecule. TMPD dihydrochloride is also an electron donor and serves as a reducing cosubstrate for heme peroxidases[1][2]. TMPD dihydrochloride is also a complex IV substrate[3].

  • CAS Number: 637-01-4
  • MF: C10H18Cl2N2
  • MW: 237.169
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: 260.6ºC at 760 mmHg
  • Melting Point: 222-224 °C(lit.)
  • Flash Point: 104.9ºC

Guignardone J

Guignardone J is the secondary metabolite isolated from endophytic fungus Phyllosticta capitalensis[1].

  • CAS Number: 1825374-57-9
  • MF: C17H24O5
  • MW: 308.37
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

10BenrichedL-4-boronophenylalanine,GMPBPA

Borofalan can be used for Boron neutron capture therapy (BNCT). Borofalan can be used for the research of recurrent or locally advanced head and neck cancer[1].

  • CAS Number: 80994-59-8
  • MF: C9H1210BNO4
  • MW: 208.209
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Pancreastatin (33-49), porcine

Pancreastatin (33-49), porcine is a pancreastatin fragment. Pancreastatin is a peptide isolated from porcine pancreas which has insulin-suppressive actions in vitro. Pancreastatin (33-49), porcine enhances the priming effect of glucose[1][2].

  • CAS Number: 106507-61-3
  • MF: C77H119N23O30
  • MW: 1846.90000
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Phaseolin

Phaseollin is an isoflavonoid phytoalexin that can be isolated from Phaseolus vulgaris . Phaseollin is toxic to bean hypocotyl and endocarp cells, and causes a complete lysis of sheep erythrocytes[1].

  • CAS Number: 13401-40-6
  • MF: C20H18O4
  • MW: 322.354
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 467.5±45.0 °C at 760 mmHg
  • Melting Point: 177-178°
  • Flash Point: 236.5±28.7 °C

Fmoc-Asp(OtBu)-OSu

Fmoc-Asp(OtBu)-Osu is an aspartic acid derivative[1].

  • CAS Number: 78553-23-8
  • MF: C27H28N2O8
  • MW: 508.52000
  • Catalog: Others
  • Density: 1.36±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 128-132ºC
  • Flash Point: N/A

H-Pro-Phe-Thr-Arg-Asn-Tyr-Tyr-Val-Arg-Ala-Val-Leu-His-Leu-OH

H-Pro-Phe-Thr-Arg-Asn-Tyr-Tyr-Val-Arg-Ala-Val-Leu-His-Leu-OH is an peptide. H-Pro-Phe-Thr-Arg-Asn-Tyr-Tyr-Val-Arg-Ala-Val-Leu-His-Leu-OH can be used for the research of various biochemical studies[1].

  • CAS Number: 158879-51-7
  • MF: C83H125N23O19
  • MW: 1749.02
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Itch-Targeting Compound 1

Itch-Targeting Compound 1 is an anti-itching agent.

  • CAS Number: 793674-76-7
  • MF: C25H36ClN3O3
  • MW: 462.02
  • Catalog: Infection
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TAT-JIP

TAT-JIP inhibits the phosphorylation of endogenous c-jun activated by PHA–PMA[1].

  • CAS Number: 1623722-15-5
  • MF: C125H220N52O27
  • MW: 2883.42
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Calceolarioside B

Calceolarioside B is a natural product isolated from Stauntonia hexaphylla leaves. Calceolarioside B exhibits significant inhibitory activity against rat lens aldose reductase (RLAR) with an IC50 of 23.99 μM. Calceolarioside B displays inhibitory effect on DPPH radical scavenging activity with an IC50 of 94.60 μM [1].

  • CAS Number: 105471-98-5
  • MF: C23H26O11
  • MW: 478.446
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 799.8±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 275.2±26.4 °C

2,2'-[[6,6,12,12-tetrakis(4-hexylphenyl)-s-indacenodithieno[3,2-b]thiophene]methylidyne(3-oxo-1H-indene-2,1(3H)-diylidene)]]bis(propanedinitrile)

ITIC, non-fullerene acceptor, is an indacenodithienothiophene-based postfullerene electron acceptor, crystallizes in a profoundly different way as compared to fullerenes.ITIC has a superior thermal stability and undergoes a glass-crystal transition considerably below its high Tg of 180 °C.

  • CAS Number: 1664293-06-4
  • MF: C94H82N4O2S4
  • MW: 1427.94000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Ala-Ser-OH

Ala-Ser is a biologically active peptide.

  • CAS Number: 3303-41-1
  • MF: C6H12N2O4
  • MW: 176.17000
  • Catalog: Others
  • Density: 1.354g/cm3
  • Boiling Point: 486.7ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 248.2ºC

3-O-Acetyl-alpha-boswellic acid

3-O-Acetyl-α-boswellic acid suppresses T cell function[1].

  • CAS Number: 89913-60-0
  • MF: C32H50O4
  • MW: 498.737
  • Catalog: Inflammation/Immunology
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 563.6±50.0 °C at 760 mmHg
  • Melting Point: 230-232℃
  • Flash Point: 170.1±23.6 °C

AMARA peptide TFA

AMARA peptide is a substrate for SIK and AMPK.

  • CAS Number: 163560-19-8
  • MF: C62H115N27O17S
  • MW: 1542.81
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Evinacumab

Evinacumab (REGN1500) is a humanised anti-ANGPTL3 (angiopoietin-like protein 3) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia[1].

  • CAS Number: 1446419-85-7
  • MF:
  • MW:
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

lutonarin

Lutonarin is a antioxidant agent that can be isolated from green barley leaves. Lutonarin inhibits malonaldehyde formation from all lipids when in combination with Saponarin (HY-N5083)[1].

  • CAS Number: 35450-86-3
  • MF: C27H30O16
  • MW: 610.52
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Val-Arg-OH

H-Val-Arg-OH is a dipeptide consisting of valine and arginine, used in biochemical research[1].

  • CAS Number: 37682-75-0
  • MF: C11H23N5O3
  • MW: 273.33200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

AZD-CO-Ph-PEG4-Ph-CO-AZD

AZD-CO-Ph-PEG4-Ph-CO-AZD is a bis-β-lactam linker can be used for antibody-siRNA conjugate synthesis[1].

  • CAS Number: 2569143-72-0
  • MF: C26H28N2O8
  • MW: 496.51
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Raddeanoside 20

Raddeanoside 20 is a triterpenoid isolated from the rhizome of Anemone raddeana. Raddeanoside 20 can suppresse superoxide generation[1].

  • CAS Number: 335354-79-5
  • MF: C47H76O17
  • MW: 913.096
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 999.7±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 286.0±27.8 °C

ANTIOXIDANT 1024

Antioxidant 1024 (MD 1024) is an antioxidant agent and metal deactivator[1].

  • CAS Number: 32687-78-8
  • MF: C34H52N2O4
  • MW: 552.788
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 652.6±55.0 °C at 760 mmHg
  • Melting Point: 60-67°C
  • Flash Point: 348.5±31.5 °C

(2S)-2-Amino(3,3,3-2H3)propan-1-ol

L-Alaninol-d3 is the deuterium labeled L-Alaninol[1].

  • CAS Number: 352438-84-7
  • MF: C3H6D3NO
  • MW: 78.128
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 174.5±0.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 83.9±0.0 °C

K1 peptide

K1 peptide is a high-affinity peptide ligand for GABAA receptor-associated protein (GABARAP)[1].

  • CAS Number: 2973365-72-7
  • MF: C71H92N16O20
  • MW: 1489.59
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-(4-Nitrophenyl)-L-glutamine

L-γ-Glutamyl-p-nitroanilide Monohydrate is a glutamic acid derivative[1].

  • CAS Number: 7300-59-6
  • MF: C11H13N3O5
  • MW: 267.238
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 590.6±50.0 °C at 760 mmHg
  • Melting Point: 185-188ºC
  • Flash Point: 311.0±30.1 °C

DTSSP Crosslinker disodium is a protein cross-linker containing a disulfide bond. DTSSP Crosslinker disodium can react with sidechains of amino acids that are within close proximity[1][2].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Glu(D-Glu-OH)-OH

Gamma-Glu-D-Glu is a biologically active peptide.

  • CAS Number: 6931-86-8
  • MF: C10H16N2O7
  • MW: 276.243
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 664.1±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 355.4±31.5 °C

GRK2 Inhibitor

GRK2 Inhibitor 1 (methyl 5-[2-(5-nitro-2-furyl)vinyl]-2-furoate) is a GRK2 (β-ARK1) inhibitor[1].

  • CAS Number: 24269-96-3
  • MF: C12H9NO6
  • MW: 263.20
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Potassium 1-naphthylacetate

1-Naphthaleneacetic acid potassium salt is a synthetic auxin, enhances the organic acid exudation in white lupin plants under phosphorus deficient conditions[1].

  • CAS Number: 15165-79-4
  • MF: C12H9KO2
  • MW: 224.297
  • Catalog: Others
  • Density: 1.233g/cm3
  • Boiling Point: 373.2ºC at 760 mmHg
  • Melting Point: 134.5-135.5ºC
  • Flash Point: 270.1ºC

((3-Fluorophenyl)sulfonyl)-L-valine

((3-Fluorophenyl)sulfonyl)-L-valine is a valine derivative[1].

  • CAS Number: 1103303-26-9
  • MF: C11H14FNO4S
  • MW: 275.30
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Maltol

Maltol, a type of aromatic compound, exists in high concentrations in red ginseng. Maltol is a potent antioxidative agent and typically is used to enhance flavor and preserve food[1].

  • CAS Number: 118-71-8
  • MF: C6H6O3
  • MW: 126.110
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 284.7±40.0 °C at 760 mmHg
  • Melting Point: 160-164 °C(lit.)
  • Flash Point: 127.3±20.8 °C

GaTx2

GaTx2 is a seletive and a high affinity inhibitor of ClC-2 channels with a voltage-dependent apparent KD of ∼20 pM. GaTx2 is a peptide toxin inhibitor from Leiurus quinquestriatus hebraeus venom. GaTx2 is useful in determining the role and the membrane localization of ClC-2 in specific cell types[1].

  • CAS Number: 194665-85-5
  • MF: C125H199N39O47S6
  • MW: 3192.54
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A