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637-01-4

637-01-4 structure
637-01-4 structure
Name N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride
Synonyms 1-N,1-N,4-N,4-N-tetramethylbenzene-1,4-diamine,dihydrochloride
MFCD00012482
N,N,N',N'-Tetramethylbenzol-1,4-diamindihydrochlorid
1,4-Benzenediamine, N,N,N,N-tetramethyl-, hydrochloride (1:2)
Wurster's reagent dihydrochloride
N,N,N',N'-Tetramethyl-P-phenylenediaminedihydrochloride
1,4-Benzenediamine, N,N,N',N'-tetramethyl-, dihydrochloride
N,N,N',N'-Tetramethylbenzene-1,4-diamine dihydrochloride
N,N,N',N'-Tetramethyl-1,4-benzenediamine dihydrochloride
EINECS 211-274-8
Description TMPD dihydrochloride, a readily oxidizable compound, is an enzymatically convert redox active substrate molecule. TMPD dihydrochloride is also an electron donor and serves as a reducing cosubstrate for heme peroxidases[1][2]. TMPD dihydrochloride is also a complex IV substrate[3].
Related Catalog
In Vitro TMPD (N,N,N′,N′-tetramethyl-para-phenylene-diamine) is used in cell culture and microbiology to differentiate organisms that exhibit cytochrome c oxidase activity and to distinguish between Gram-negative and Gram-positive pathogenic and non-pathogenic bacteria. The concept of TMPD oxidation by microorganisms is widely used and is known as a successful colorimetric indicator for bacterial oxidases, as the radical cation TMPD+˙, formed by oxidation, shows a characteristic deep blue colour. The electrochemical recognition of the TMPD oxidation by bacterial oxidases can be applied to a variety of pathogens[1].
References

[1]. S Kuss, et al. Electrochemical recognition and quantification of cytochrome c expression in Bacillus subtilis and aerobe/anaerobe Escherichia coli using N, N, N', N'-tetramethyl- para-phenylene-diamine (TMPD). Chem Sci. 2017 Nov 1;8(11):7682-7688.

[2]. Nenad Petrovic, et al. Using N,N,N',N'-tetramethyl-p-phenylenediamine (TMPD) to assay cyclooxygenase activity in vitro. Methods Mol Biol. 2010;594:129-40.

[3]. Franco A Rossato, et al. Fatty acid synthase inhibitors induce apoptosis in non-tumorigenic melan-a cells associated with inhibition of mitochondrial respiration. PLoS One. 2014 Jun 25;9(6):e101060.
Boiling Point 260.6ºC at 760 mmHg
Melting Point 222-224 °C(lit.)
Molecular Formula C10H18Cl2N2
Molecular Weight 237.169
Flash Point 104.9ºC
Exact Mass 236.084702
PSA 6.48000
LogP 3.42260
Storage condition Store at RT.
Stability Stable. Incompatible with strong oxidizing agents, strong bases.
Water Solubility SOLUBLE
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R20/21/22
Safety Phrases S26-S36-S36/37
RIDADR 2811
WGK Germany 3
Packaging Group II
Hazard Class 6.1(a)
HS Code 29215190
100-22-1 structure

100-22-1

~%

637-01-4 structure

637-01-4

Literature: Journal of Physical Chemistry, , vol. 95, # 16 p. 6218 - 6227
HS Code 2921519090
Summary 2921519090. o-, m-, p-phenylenediamine, diaminotoluenes, and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:17.0%. . MFN tariff:6.5%. General tariff:30.0%
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title: CAS No. 637-01-4 | Chemsrc address: https://www.chemsrc.com/en/baike/1095967.html

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