Peroxidase actively involves in oxidizing reactive oxygen species, innate immunity, hormone biosynthesis and pathogenesis of several diseases[1].
α-curcumene (compound 12) is isolated from the essential oil of rhizomes of Curcuma aromatica and can be synthesized artificially[1].
BTA-EG4 is a catalase-amyloid interaction inhibitor, which can significantly enhance the neurotoxicity of amyloid peptides in catalase-overexpressing neuronal cells, and can be used in the study of neurodegenerative diseases[1].
4-Oxododecanedioic acid is a fatty acid derivative[1].
Boc-D-4-Pal-OH is an alanine derivative[1].
A dual inhibitor of TNF-α and TGF-β1 by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation; attenuates the LPS/GaIN-induced hepatic inflammation in the mice, and downregulates TGF-β1-induced fibrotic gene expression; attenuates renal inflammation and fibrosis with the downregulation of inflammatory cytokines and fibrotic gene expressions in renal fibrosis model.
Herbacetin is a natural flavonoid from flaxseed, exerts various pharmacological activities, including antioxidant, anti-inflammatory and anticancer effects[1]. Herbacetin is an Ornithine decarboxylase (ODC) allosteric inhibitor, directly binds to Asp44, Asp243, and Glu384 on ODC. Ornithine decarboxylase (ODC) is a rate-limiting enzyme in the first step of polyamine biosynthesis[2].
Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)-d4 is the deuterium labeled Thymine-α,α,α,6-d4 Glycol (mixture of diastereomers)[1].
1,4-Benzenedimethanol-d4 is the deuterium labeled 1,4-Benzenedimethanol[1].
Picropodophyllin-4-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside (compound 17) is a lignan isolated from the roots and rhizomes of Podophyllum sinensis[1].
XmAb 5592 is a humanized, Fc-engineered anti-HM1.24 antibody with enhanced binding to FcγRIIIa and FcγRIIa receptors, augments HM1.24-specific multiple myeloma (MM) cells lysis in vitro via antibody-dependent cellular cytotoxicity (ADCC) and antibody dependent cellular phagocytosis (ADCP)[1].
Phosphorylcholine is an antigenic cell-surface component found on many commensal and pathogenic bacteria that reside in the upper airway.
2-Hydroxynaringenin is a flavonoid. 2-Hydroxynaringenin can be isolated from Paeoniae Alba[1][2].
Phosphatase Binder-1 (comppund i-196) provides bifunctional compounds that efficiently dephosphorylate certain phospho-activated target proteins. Phosphatase Binder-1 plays an important role in cancer[1].
Cyanidin 3-sophoroside-5-glucoside is the main anthocyanin in purple-fleshed sweet potato and affects the antioxidant activity of purple-fleshed sweet potato[1].
5-Methyl-5,6-dihydrouridine is a minor constituent in the chromosomal RNA of the rat ascites tumor. 5-Methyl-5,6-dihydrouridine can be used for nucleic acid modification[1].
H-Cys(Acm)-OH is a cysteine[1].
Butabindide (UCL-1397) oxalate is a potent, selective tripeptidvl peptidase II (TPP II) inhibitor with Ki values of 7 nM and 10 μM for TPP II and TPP I, respectively. Butabindide oxalate inhibits TPP II to protect CCK-8 against inactivation[1][2].
Indicine (Compound 3) is an alkaloid. Indicine can reduce pyrrolizine alkaloids (PA) [1].
Apyramide is an anti-inflammatory agent.
Ecromeximab (KM 871; KW 2871) is a mouse-derived IgG-κ chimeric antibody targeting ganglioside GD3. Ecromeximab is expressed by YB2/0 rat hybridoma cells[1].
Bacopaside N1 is a diglycosidic saponin[1].
(S)-2-[(tert-Butoxycarbonyl)amino]-3-iodopropionic acid methyl ester is an alanine derivative[1].
1,2-Diphenylethyne-d10 is the deuterium labeled 1,2-Diphenylethyne[1].
Lupulone C (Compound 9) is an inhibitor of NO production[1].
Soyasapogenol D is a methyl-trimethylsilyl derivative of the sapogenin[1].
(4-Hydroxy-1,1-dioxidotetrahydrothiophen-3-yl)glycine is a Glycine (HY-Y0966) derivative[1].
GYY4137 is a slow releasing H2S donor with vasodilator and antihypertensive activity. GYY4137 also exhibits anti-inflammatory and anticancer activity[1][2][3].
(Z)-Aconitic acid (cis-Aconitic acid) is the cis-isomer of Aconitic acid. (Z)-Aconitic acid (cis-Aconitic acid) is an intermediate in the tricarboxylic acid cycle produced by the dehydration of citric acid.
Testololactone is an aromatase inhibitor. Testololactone can be used for research of breast carcinoma[1].