Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Hsp70-derived octapeptide

Hsp70-derived octapeptide is a conserved octapeptide of the C-terminal end of Hsp70, which physically interacts with tetratricopeptide repeat (TPR) motifs[1][2].

  • CAS Number: 736171-62-3
  • MF: C36H58N8O16
  • MW: 858.89
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Plumbagin

Plumbagin (2-Methyljuglone) is a naphthoquinone isolated from Plumbago zeylanica L, exhibits anticancer and antiproliferative activities[1].

  • CAS Number: 481-42-5
  • MF: C11H8O3
  • MW: 188.17900
  • Catalog: Cancer
  • Density: 1.354g/cm3
  • Boiling Point: 383.9ºC at 760 mmHg
  • Melting Point: 76-78ºC(lit.)
  • Flash Point: 200.2ºC

alpha-d-mannopyranosylphenyl isothiocyanate

4-Isothiocyanatophenyl α-D-Mannopyranoside, an organic isothiocyanate, is a building block and reagent which is used for preparing neoglycoproteins[1].

  • CAS Number: 96345-79-8
  • MF: C13H15NO6S
  • MW: 313.32600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 180-181ºC
  • Flash Point: N/A

Hexa-L-Tyrosine

Tyr-Tyr-Tyr-Tyr-Tyr-Tyr is a tyrosine derivative[1].

  • CAS Number: 6934-38-9
  • MF: C54H56N6O13
  • MW: 997.05500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

IQB-782

IQB-782 is a cysteine derivative. IQB-782 has inhibition for thrombin activatable fibrinolysis inhibitor (TAFI), with an Ki(app) of 0.14 μM. IQB-782 shows a potent mucolytic-expectorant activity[1][2].

  • CAS Number: 40454-21-5
  • MF: C4H9N3O2S
  • MW: 163.19800
  • Catalog: Cardiovascular Disease
  • Density: 1.66g/cm3
  • Boiling Point: 348.5ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 164.5ºC

diSulfo-Cy3 alkyne

diSulfo-Cy3 alkyne is a water-soluble dye and a Click Chemistry reagent containing an azide group. Absorbance and emission of the dye are identical to Cy3 fluorophore. diSulfo-Cy3 alkyne can be used for the labeling of proteins, and even intact biological objects in water phase[1].

  • CAS Number: 2055138-88-8
  • MF: C33H38N3NaO7S2
  • MW: 675.79
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Kemptide (amide)

Kemptide (amide) is a heptapeptide with properties of a cytophilic substrate. Kemptide is a molecule preserving cell membrane intactness, is phosphorylated by PKI, the inhibitory protein specific for cAMP-dependent protein kinase (PK)[1].

  • CAS Number: 70691-36-0
  • MF: C32H62N14O8
  • MW: 770.92400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Nicotredole

Nicotredole (Tryptamide) is an orally active anti-inflammatory and analgesic agent. Nicotredole exhibits evident antiinflammatory effects of potency comparable with Phenylbutazone. Nicotredole has only weak ulcerogenic activity[1][2][3].

  • CAS Number: 29876-14-0
  • MF: C16H15N3O
  • MW: 265.310
  • Catalog: Inflammation/Immunology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 588.4±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 309.7±25.9 °C

Monomethyl auristatin E intermediate-11

Monomethyl auristatin E intermediate-11 is an intermediate reactant in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].

  • CAS Number: 870640-62-3
  • MF: C14H23NO
  • MW: 221.33852
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BCIP

BCIP(BCIP p-toluidine salt; X-phosphate p-toluidine salt) is an artificial chromogenic substrate used for the sensitive colorimetric detection of alkaline phosphatase activity.

  • CAS Number: 6578-06-9
  • MF: C15H15BrClN2O4P
  • MW: 433.621
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: 580.2ºC at 760 mmHg
  • Melting Point: 194-195ºC
  • Flash Point: 304.7ºC

Adipate-13C6 sodium

Adipate-13C6 (sodium) is the 13C labeled Sodium adipate[1].

  • CAS Number: 2483735-36-8
  • MF: 13C6H8Na2O4
  • MW: 196.06
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Gly-Arg-OH

H-Gly-Arg-OH is adipeptide.

  • CAS Number: 18635-55-7
  • MF: C8H17N5O3
  • MW: 231.25
  • Catalog: Others
  • Density: 1.51g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Dihydroseselin

Dihydroseselin is a 7-hydroxycoumarin (HY-N0573) derivative. 7-hydroxycoumarin is a natural product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent[1]

  • CAS Number: 2221-66-1
  • MF: C14H14O3
  • MW: 230.25900
  • Catalog: Others
  • Density: 1.190±0.06 g/cm3(Predicted)
  • Boiling Point: 387.3±42.0 °C(Predicted)
  • Melting Point: 104-105 °C
  • Flash Point: N/A

Mildronate

Mildronate (Meldonium) functions as a cardioprotective drug by cpmpetetively inhibiting BBOX1 and OCTN2. Mildronate (Meldonium) exhibits IC50 values of 34-62 μM for human recombinant BBOX and an EC50 of 21 μM for human OCTN2. Mildronate (Meldonium) treatment-induced redirection of long-chain FA metabolism from mitochondria to peroxisomes[1].

  • CAS Number: 76144-81-5
  • MF: C6H14N2O2
  • MW: 146.188
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 85-90ºC
  • Flash Point: N/A

Fluometuron-d6

Fluometuron-d6 is the deuterium labeled 4-Nitrobenzaldehyde[1].

  • CAS Number: 2030182-29-5
  • MF: C10H5D6F3N2O
  • MW: 238.24
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Insulin-Like Growth Factor I (30-41)

IGF-I (30-41) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions)[1].

  • CAS Number: 82177-09-1
  • MF: C51H83N19O19
  • MW: 1266.34
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sominone

Sominone is a withanolide. Sominone can be isolated from the herbs of Withania somnifera[1].

  • CAS Number: 98569-64-3
  • MF: C28H42O5
  • MW: 458.63000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(Rac)-cis-3-hydroxy glyburide-13C,d3

(Rac)-cis-3-hydroxy glyburide-13C,d3 is a 13C-labeled and deuterium labeled (Rac)-cis-3-hydroxy glyburide[1].

  • CAS Number: 1217848-91-3
  • MF: C2213CH25D3ClN3O6S
  • MW: 514.01
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-Methoxy-2-benzimidazolethiol

5-Methoxy-2-benzimidazolethiol is a benzimidazole. The iodimetric determination of 5-Methoxy-2-benzimidazolethiol in alkaline media is studied[1].

  • CAS Number: 37052-78-1
  • MF: C8H8N2OS
  • MW: 180.227
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 309.4±44.0 °C at 760 mmHg
  • Melting Point: 261-263 °C(lit.)
  • Flash Point: 140.9±28.4 °C

Siraitic acid B

Siraitic Acid B is a cucurbitane triterpenoid isolated from the root of S. grosvenori [1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-(3-hydroxyphenyl)-Arachidonoyl amide

N-(3-Hydroxyphenyl)-arachidonoyl amide (Compound 23) is an anandamide transport inhibitor with an IC50 of 21.3 μM[1].

  • CAS Number: 183718-75-4
  • MF: C26H37NO2
  • MW: 395.58
  • Catalog: Neurological Disease
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 579.4±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 304.2±30.1 °C

4,4'-Sulfonyldiphenol-d8

4,4'-Sulfonyldiphenol-d8 is the deuterium labeled 4,4'-Sulfonyldiphenol[1].

  • CAS Number: 2483831-28-1
  • MF: C12H2D8O4S
  • MW: 258.32
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

6-Acetonyldihydrosanguinarine

6-Acetonyldihydrosanguinarine is a compound isolated from the aerial parts of Chelidonium majus L..[1]

  • CAS Number: 37687-34-6
  • MF: C23H19NO5
  • MW: 389.401
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 597.3±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 315.0±30.1 °C

2-Methyl-5-acetonyl-7-hydroxychromone

Cassiachromone can be isoalted from Cassia siamea[1].

  • CAS Number: 28955-30-8
  • MF: C13H12O4
  • MW: 232.232
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 444.7±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 174.8±22.2 °C

N-(3-NITRO-2-PYRIDINESULFENYL)-L-GLUTAMIC ACID GAMMA-T-BUTYL ESTER

N-(3-Nitro-2-pyridinesulfenyl)-L-glutamic acid γ-t-butyl ester is a glutamic acid derivative[1].

  • CAS Number: 108312-25-0
  • MF: C14H19N3O6S
  • MW: 357.38200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

LysoTracker Red

LysoTracker Red (LysoTracker Red DND-99) is a paraformaldehyde fixable probe that concentrates into acidic compartments of cells and tissues. LysoTracker Red is an indicator of cell death in a manner similar to other standard assays (Annexin, terminal dUTP nick end labeling, Nile blue sulfate, neutral red, and acridine orange)[1]. LysoTracker Red is a marker for late endosomes and lysosomes[2].

  • CAS Number: 231946-72-8
  • MF: C20H24BF2N5O
  • MW: 399.25
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(-)-Haplomyrfolin

(-)-Haplomyrfolin is a natural lignan with anticancer effects[1].

  • CAS Number: 85404-48-4
  • MF: C20H20O6
  • MW: 356.36900
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-D-Allylglycine dicyclohexylamine salt

Boc-D-Gly(allyl)-OH.DCHA is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 221352-64-3
  • MF: C22H40N2O4
  • MW: 396.564
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

10-Hydroxyaloin B

10-Hydroxyaloin B is a bioactive oxanthrone based on the aloin skeleton[1].

  • CAS Number: 134863-92-6
  • MF: C21H22O10
  • MW: 434.39
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cuniloside B

Cuniloside B (Eucalmaidin E) is a non-volatile glucose monoterpene ester. Cuniloside B can be used as a fragrance additive[1].

  • CAS Number: 1187303-40-7
  • MF: C26H40O10
  • MW: 512.590
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 680.4±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 221.3±25.0 °C