Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Bis(2-Chloroethyl)amine hydrochloride-d8

Bis(2-Chloroethyl)amine hydrochloride-d8 is the deuterium labeled Bis(2-Chloroethyl)amine hydrochloride[1].

  • CAS Number: 102092-04-6
  • MF: C4Cl3D10N
  • MW: 188.55000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sulfo-Cy3 DBCO

DBCO-Cy3 (DBCO-Sulfo-Cy3) is the derivative of Cyanine3 fluorophore, a pH insensitive from pH (4-10) orange fluorescent dye with excitation maximum 555 nm and emission maximum of 580 nm. DBCO-Cy3 has fast reaction kinetics and good stability, and is productive to use in many standard fluorescent instrumentations.

  • CAS Number: 1782950-79-1
  • MF: C50H54N4O11S3
  • MW: 983.18
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hydroxylapatite

Hydroxylapatite (Hydroxyapatite) is a naturally occurring calcium phosphate which is a major mineral component of bone and teeth bones. Nano-scale Hydroxylapatite particles are increasingly being used as carriers for controlled and targeted delivery of bioactive agents like drugs, proteins, and nucleic acids due to their high porosity, negative charge, and biodegradability [1].

  • CAS Number: 1306-06-5
  • MF: Ca2HO5P
  • MW: 502.311
  • Catalog: Others
  • Density: 3.140 g/cm3
  • Boiling Point: 158ºC at 760 mmHg
  • Melting Point: 1100 °C(lit.)
  • Flash Point: N/A

Biotinyl-Amylin (human) trifluoroacetate salt

Biotinyl-Amylin (human) is abiotinylated Amylin, amide, human (HY-P1070).

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A
  • CAS Number: 7132-64-1
  • MF: C16H32O2
  • MW: 256.42400
  • Catalog: Others
  • Density: 0.865 g/mL at 20 °C
  • Boiling Point: 141-142 °C3 mm Hg(lit.)
  • Melting Point: 18-19 °C(lit.)
  • Flash Point: >230 °F

Bis(2H4)ammonium sulfate

Ammonium sulphate-d8 is the deuterium labeled Ammonium sulphate,≥99.0%,AR[1]. Ammonium sulphate,≥99.0%,AR is an inorganic sulfate salt used for molecular biology[2].

  • CAS Number: 13814-01-2
  • MF: D8N2O4S
  • MW: 140.189
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: >280ºC (dec.)(lit.)
  • Flash Point: N/A

9-Methoxyaristolactam I

9-Methoxyaristolactam I is a natural product that can be isolated from the roots of Asarum sieboldii Miq. var. Seoulense Nakai[1].

  • CAS Number: 133462-30-3
  • MF: C18H13NO5
  • MW: 323.30
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Phenylbenzothiazole-PEG4-OH

Phenylbenzothiazole-PEG4-OH (compound 1) can treat spinal cord injury and promote spine formation[1].

  • CAS Number: 2274723-90-7
  • MF: C21H25NO5S
  • MW: 403.49
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Carbobenzyloxy-L-alanine

N-[(Benzyloxy)carbonyl]-L-alanine is an alanine derivative[1].

  • CAS Number: 1142-20-7
  • MF: C11H13NO4
  • MW: 223.225
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 422.1±38.0 °C at 760 mmHg
  • Melting Point: 82-84ºC
  • Flash Point: 209.1±26.8 °C

Traxillaside

Traxillaside is a plant-derived lignan[1] with neuroprotective properties[2].

  • CAS Number: 149415-62-3
  • MF: C28H36O12
  • MW: 564.578
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Des-[Gly77,His78] Myelin Basic Protein (68-84), bovine

Des-[Gly77,His78] Myelin Basic Protein (68-84) is a 68-84 sequence fragment of guinea pig myelin basic protein (GPMBP). Des-[Gly77,His78] Myelin Basic Protein (68-84) regulates functionally diverse encephalitogenic and proliferative activities of experimental autoimmune encephalomyelitis (EAE)-associated T cells[1].

  • CAS Number: 98474-60-3
  • MF: C73H115N23O26
  • MW: 1730.833
  • Catalog: Neurological Disease
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Hexadecylpyridin-1-ium bromide-d5

1-Hexadecylpyridin-1-ium bromide-d5 is the deuterium labeled 1-Hexadecylpyridin-1-ium bromide[1].

  • CAS Number: 143715-91-7
  • MF: C21H33BrD5N
  • MW: 389.46800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

EE epitope

EE epitope is a biological active peptide. (This peptide is a 314 to 319 amino acids fragment of the middle T antigen of mouse polymavirus. Glu-Glu epitope peptide is widely used as an epitope tag.Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)

  • CAS Number: 221216-83-7
  • MF: C34H50N6O12S2
  • MW: 798.92
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-[[(2E)-3-[4-(D-glucopyranosyloxy)-3-hydroxyphenyl]-1-oxo-2-propen-1-yl]oxy]-1,4,5-trihydroxy-(1S,3R,4R,5R)-Cyclohexanecarboxylic acid

5-O-(3'-O-Glucosylcaffeoyl)quinic acid (compound 19) is a phenolic compound found in the leaves of Ilex glabra L. Gray (Aquifoliaceae)[1].

  • CAS Number: 1629852-63-6
  • MF: C22H28O14
  • MW: 516.44932
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

benfluralin

Benfluralin is a kind of herbicide and an agrochemical which can be used as a pre-emergence herbicide used for the control of grass and other weeds in a range of food and non-food crops.

  • CAS Number: 1861-40-1
  • MF: C13H16F3N3O4
  • MW: 335.279
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 369.1±42.0 °C at 760 mmHg
  • Melting Point: 65 - 67ºC
  • Flash Point: 177.0±27.9 °C

8-Hydroxy-3,5,6,7,3',4'-hexamethoxyflavone

8-Hydroxy-3,5,6,7,3',4'-hexamethoxyflavone is a polymethoxyflavone (PMF) isolated from pericarpium citri reticulatae.

  • CAS Number: 1000415-56-4
  • MF: C21H22O9
  • MW: 418.40
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Febuxostat dicarboxylic acid impurity

Febuxostat dicarboxylic acid impurity is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM[1].

  • CAS Number: 1239233-87-4
  • MF: C16H17NO5S
  • MW: 335.375
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 568.9±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 297.9±32.9 °C

tert-Butyl (1-hydroxypropan-2-yl)carbamate-d6

tert-Butyl (1-hydroxypropan-2-yl)carbamate-d6 is the deuterium labeled tert-Butyl (1-hydroxypropan-2-yl)carbamate[1].

  • CAS Number: 2243764-35-2
  • MF: C8H11D6NO3
  • MW: 181.26
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

NT1-014B

NT1-014B is a potent NT1-lipidoid encapsulated AmB (amphotericin B). NT1-014B dopes the NT-lipidoids into BBB-impermeable lipid nanoparticles (LNPs) gave the LNPs the ability to cross the BBB. NT1-014B enhances brain delivery through intravenous injection[1].

  • CAS Number: 2739805-64-0
  • MF: C40H68N2O4S4
  • MW: 769.2
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Myelin Oligodendrocyte Glycoprotein (40-54), Rat, Mouse

Myelin Oligodendrocyte Glycoprotein (40-54), Rat, Mouse (MOG (40-54)) is a CD8-related self-antigenic epitope of the myelin oligodendrocyte glycoprotein (MOG) protein and is presented in association with H-2Db[1].

  • CAS Number: 507233-87-6
  • MF: C84H127N27O21
  • MW: 1851.08
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Naphthalenealanine

2-Amino-3-(naphthalen-1-yl)propanoic acid is an alanine derivative[1].

  • CAS Number: 28095-56-9
  • MF: C13H13NO2
  • MW: 215.248
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 412.3±33.0 °C at 760 mmHg
  • Melting Point: 239℃
  • Flash Point: 203.2±25.4 °C

Vanillyl alcohol

Vanillyl alcohol (Vanillic alcohol), derived from vanillin, is a phenolic alcohol and is used as a flavoring agent in foods and beverages[1].

  • CAS Number: 498-00-0
  • MF: C8H10O3
  • MW: 154.163
  • Catalog: TRP Channel
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 313.1±27.0 °C at 760 mmHg
  • Melting Point: 110-117 °C(lit.)
  • Flash Point: 143.2±23.7 °C

KALA

KALA is an amphiphilic peptide that forms an α-helical structure at physiological pH. KALA modifies a plasmid DNA-encapsulating liposomal membrane and is used as a fusogenic peptide in order to achieve effective liver targeting and transfection of DNA via galactose receptors[1].

  • CAS Number: 187987-64-0
  • MF: C144H248N40O35S
  • MW: 3131.822
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 2669.2±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 1568.1±34.3 °C

Ascorbic acid

2-O-β-D-Glucopyranosyl-L-ascorbic acid (AA-2βG), isolated from Lycium Fruit, is a stable vitamin C analog with anti-tumor activity[1].

  • CAS Number: 562043-82-7
  • MF: C12H18O11
  • MW: 338.26472
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Pierreione B

Pierreione B is a pyranoisoflavone, that can be isolated from the leaves and twigs of Antheroporum pierrei. Pierreione B demonstrates solid tumor selectivity with minimal cytotoxicity[1].

  • CAS Number: 1292766-21-2
  • MF: C26H28O7
  • MW: 452.50
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 647.8±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 218.5±25.0 °C

Predef

Isoflupredone acetate is a corticosteroids with anti-inflammatory activity. Isoflupredone acetate can be used for research ketosis, musculoskeletal disorders, hypersensitivity, infections, inflammatory diseases in cows, horse, pigs, et al.[1][2].

  • CAS Number: 338-98-7
  • MF: C23H29FO6
  • MW: 420.471
  • Catalog: Infection
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 576.5±50.0 °C at 760 mmHg
  • Melting Point: 244-246 °C
  • Flash Point: 302.5±30.1 °C

Kaempferol 3-O-beta-(6''-p-coumaroyl)glucopyranosyl(1->2)-alpha-L-rhamnopyranoside

Kaempferol-3-O-(6'''-trans-p-coumaroyl-2''-glucosyl)rhamnoside is a natural antioxidant from herbal medicines[1].

  • CAS Number: 111957-48-3
  • MF: C36H36O17
  • MW: 740.661
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 1056.4±65.0 °C at 760 mmHg
  • Melting Point: 195 ºC
  • Flash Point: 331.7±27.8 °C

((3-Chlorophenyl)sulfonyl)proline

((3-Chlorophenyl)sulfonyl)proline is a proline derivative containing amino and carboxyl groups.

  • CAS Number: 1164136-21-3
  • MF: C11H12ClNO4S
  • MW: 289.74
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cyanidin-3-O-rutinoside chloride

Keracyanin chloride (Cyanidin 3-rutinoside chloride), an anthocyanin, has antioxidant activity. Keracyanin chloride inhibits malonaldehyde formation in oxidized calf thymus DNA[1][2].

  • CAS Number: 18719-76-1
  • MF: C27H31ClO15
  • MW: 630.979
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Peptide YY Fragment 3-36 human

Peptide YY (PYY) (3-36), human is a gut hormone peptide that acts as a Y2 receptor agonist to reduce appetite.

  • CAS Number: 126339-09-1
  • MF: C176H272N52O54
  • MW: 3980.42
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A