17α-Hydroxyprogesterone acetate possesses progestational activity. 17α-Hydroxyprogesterone acetate has antiinflammatory effects at the murine maternal-fetal interface[1][2].
Antioxidant agent-7 (SD-7) is a benzodiazepine derivative with antioxidant activity with an IC50 value of 470 nM to scavenge DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical[1].
Calcium Green 1AM is a cell-permeant fluorescent calcium indicator (Excitation 506 nm; Emission 531 nm). Calcium Green 1AM is converted to the fluorescent calcium indicator by intracellular esterases[1].
Hulupinic acid is a prominent oxidation product of hop acids[1].
Fmoc-Glu-O-2-PhiPr is a glutamic acid derivative[1].
6PPD-quinone-d5 is the deuterium labeled 6PPD-quinone[1].
(S)-IDO1-IN-5 is the S-isomer of IDO1-IN-5. IDO1-IN-5 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[1].
2-Acetamidofluorene is a potent carcinogenan. 2-Acetamidofluorene is can be used fot induction of hepatocellular carcinoma (HCC) and multiple primary tumours[1][2].
GIP (1-39) (Gastric inhibitory peptide (1-39) (porcine)) is an insulinotropic peptide that stimulats insulin secretion from rat pancreatic islets. GIP (1-39) at 100 nM was able to significantly increase intracellular Ca2+ concentration ([Ca2+]i), and capable of enhancing exocytosis[1].
Allitol is a rare natural polyol that can be used as a sweetener. Allitol is an important intermediate for the preparation of the agents which against diabetes, cancer, and viral infections, including AIDS[1].
DL-Goitrin, also called (R, S)- report by the spring, consists of the epigoitrin (reported by the R- Spring) and the spring (-S- reported by spring), and the two mutually isomers, and the mixture is the ingredient of Radix[1].
Yibeinoside A is an alkaloid isolated from the bulb of Fritillaria pallidiflora Schreb [1].
Mulberrin is a strong inhibitor of organic anion-transporting polypeptide 2B1 (OATP2B1)-mediated estrone-3-sulfate (E3S) uptake with an IC50 value being 1.8 ±1.5 μM.
L-Isoserine is a serine derivative[1].
Anticancer agent 149 (compound 3) is an anticancer agent isolated from the rhizome of Dioscorea dioscorea (DM). Anticancer agent 149 exhibits selective cytotoxic activity against MCF-7 cells (IC50=31.41 μM)[1].
Clothianidin-2-S-propanoic acid is a clothianidin hapten. Clothianidin-2-S-propanoic can be used for the research of insecticide[1].
5,5'-Dinitro BAPTA AM is a membrane-permeant, high-affinity calcium chelator, it can be used for investigation of the role of cytosolic Ca2+. 5,5'-Dinitro BAPTA AM can be loaded by incubation into live cells, and is cleaved by cytosolic esterases to liberate the active tetra-carboxylate ligand[1].
6''-O-trans-Feruloylcatalpol is a natural iridoid glycoside compound[1].
1,2,3,5-Tetramethylbenzene-d14 is the deuterium labeled 1,2,3,5-Tetramethylbenzene[1].
Prohexadione (BX-112 free acid) is a plant growth regulator. Prohexadione inhibits gibberellin biosynthesis of plants[1][2].
Hydrazine-d6 (sulfate) is the deuterium labeled Hydrazine sulfate[1].
Dehydroeburicoic acid monoacetate (Compound 18) is a lanostane triterpenoid isolated from Wolfiporia cocos[1].
Tetra-N-acetylchitotetraose elicits plant defense systems. Tetra-N-acetylchitotetraose is a component of the hpo-chitoo gosacchaπdes (LCOs) secreted from Rhizobia. Tetra-N-acetylchitotetraose is also a substrate for the Rhizobium leguminosarum nodulation protein NodB, a CO deacetylase[1].
Imexon is an iminopyrrolidone aziridine with anti-cancer activity.
2'-O-MOE-U is an oligonucleotide, can be used for oligonucleotide synthesis[1].
Iriflophenone, isolated from Aquilaria sinensis, stimulates MCF-7 and T-47D human breast cancer cells proliferation[1][2].
Glyoxalase I inhibitor 7 (Compound 6) is a glyoxalase I (Glo-I) inhibitor with an IC50 of 3.65 μM. Glyoxalase I inhibitor 7 can be used as anticancer agent[1].
Calpain inhibitors are lipophilic and show moderate to good antiproliferative activity in vitro compared with melanoma cell lines (a-375 and b-16f1) and PC-3 prostate cancer cells. In addition, a member of this group (compound 3) expressed 2 μ M concentration inhibited the invasion of DU-145 cells by 80%.
Isodemethylwedelolactone is a kind of procoagulant and haemolytic constituent isolated from Eclipta alba[1].
Valpromide is an amide derivative of valproic acid and inhibits human epoxide hydrolase.