Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Valpromide
Price: ￥666.0/50mg ￥806.0/100mg ￥466.0/10mg
Purity: 97.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Valpromide
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

2430-27-5

2430-27-5 structure

2430-27-5 structure

Name: Valpromide
Chemical Name: valpromide
CAS Number: 2430-27-5
Molecular Formula: C₈H₁₇NO
Molecular Weight: 143.22700
Catalog: API Nervous system medication Antiepileptic and anticonvulsant
Create Date: 2018-07-12 20:33:55
Modify Date: 2024-01-05 01:56:50
Valpromide is an amide derivative of valproic acid and inhibits human epoxide hydrolase.

Name	valpromide
Synonyms	Depamide 2-Propylvaleramide Valpromide 2,2-Di-n-propylacetamide Pentanamide,2-propyl EINECS 219-394-2 MFCD00051534 2-Ethylvaleramide 2-propylpentamide 2,2-BIS(TRIFLUOROMETHYL)PROPANOL 2-propylpentanamide Dipropylacetamide Valpramide

Description	Valpromide is an amide derivative of valproic acid and inhibits human epoxide hydrolase.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Infection Research Areas >> Neurological Disease
Target	epoxide hydrolase[1]
References	[1]. Pacifici GM, et al. Valpromide inhibits human epoxide hydrolase. Br J Clin Pharmacol. 1986 Sep;22(3):269-74. [2]. Gorres KL, et al. Valpromide Inhibits Lytic Cycle Reactivation of Epstein-Barr Virus. MBio. 2016 Mar 1;7(2):e00113.

Density	0.885g/cm3
Boiling Point	274.6ºC at 760mmHg
Melting Point	123-125°C
Molecular Formula	C₈H₁₇NO
Molecular Weight	143.22700
Flash Point	119.9ºC
Exact Mass	143.13100
PSA	43.09000
LogP	2.38840
Vapour Pressure	0.00535mmHg at 25°C
Index of Refraction	1.44
Storage condition	room temp

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YV5965500

CHEMICAL NAME :: Valeramide, 2-propyl-

CAS REGISTRY NUMBER :: 2430-27-5

BEILSTEIN REFERENCE NO. :: 1750444

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C8-H17-N-O

MOLECULAR WEIGHT :: 143.26

WISWESSER LINE NOTATION :: ZVY3&3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 890 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GNAW "Pharmacodynamie de l'Acide Dipropylacetique (ou Propyl-2-Pentanoique) et de ses Amides," Carraz, G., Imprimerie Eymond, 1968 Volume(issue)/page/year: -,72,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 950 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GNAW "Pharmacodynamie de l'Acide Dipropylacetique (ou Propyl-2-Pentanoique) et de ses Amides," Carraz, G., Imprimerie Eymond, 1968 Volume(issue)/page/year: -,71,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 438 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1980- Volume(issue)/page/year: 9,37,1988 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 600 mg/kg

SEX/DURATION :: female 8 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetal death

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 6,669,1986

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Hazard Codes	Xn
Risk Phrases	R22
Safety Phrases	S22-S36/37
RIDADR	NONH for all modes of transport
RTECS	YV5965500
HS Code	2924199090

HS Code	2924199090
Summary	2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%