Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Phosphatidylinositol 4,5-bisphosphate

Phosphatidylinositol 4,5-bisphosphate (L-alpha-Phosphatidylinositol-4,5-bisphosphate), a phospholipid component of cell membranes, is a substrate for phospholipase C (PLC) and phosphoinositide 3-kinase (PI3K) and as a primary messenger[1][2][3].

  • CAS Number: 245126-95-8
  • MF: C47H85O19P3
  • MW: 1047.088
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 1034.8±75.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 579.6±37.1 °C

z-d-chg-oh

Z-D-Chg-OH is a glycine derivative that can be used for amino acid synthesis[1].

  • CAS Number: 69901-85-5
  • MF: C8H15NO2
  • MW: 157.210
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 292.8±23.0 °C at 760 mmHg
  • Melting Point: 103℃
  • Flash Point: 130.9±22.6 °C

D-Lys(Z)-Pro-Arg-pNA diacetate

D-Lys(Z)-Pro-Arg-pNA (diacetate) diacetate is a chromogenic substrate. Sequence: D-Lys(Z)-Pro-Arg-pNA.

  • CAS Number: 108963-70-8
  • MF: C35H51N9O11
  • MW: 773.833
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ganglioside GM1

Ganglioside GM1 is a member of the ganglioside family that can be used for neurological disease research. Ganglioside GM1 is a functional tissue receptor for the Cholera Toxin1[1].

  • CAS Number: 37758-47-7
  • MF: C77H139N3O31
  • MW: 1602.93000
  • Catalog: Neurological Disease
  • Density: 1.35 g/cm3
  • Boiling Point: 1527ºC at 760 mmHg
  • Melting Point: 207-230ºC
  • Flash Point: 877.3ºC

(S)-(-)-1-Ethyl-2-pyrrolidinecarboxamide

(S)-(-)-1-Ethyl-2-pyrrolidinecarboxamide is a proline derivative[1].

  • CAS Number: 114812-34-9
  • MF: C7H14N2O
  • MW: 142.19900
  • Catalog: Others
  • Density: 1.047g/cm3
  • Boiling Point: 283.5ºC at 760 mmHg
  • Melting Point: 110ºC
  • Flash Point: 125.3ºC

5-Methoxy-1H-benzo[d]imidazole-d3

5-Methoxy-1H-benzo[d]imidazole-d3 is the deuterium labeled 5-Methoxy-1H-benzo[d]imidazole[1].

  • CAS Number: 1219805-69-2
  • MF: C8H8N2O
  • MW: 148.162
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 390.2±15.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 141.7±10.6 °C

Antifungal agent 21

Antifungal agent 21 is a promising candidate in the development of new agrochemical antifungal agents.

  • CAS Number: 1622299-33-5
  • MF: C11H14O3
  • MW: 194.23
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BMS-593214

BMS-593214 is an active site-directed factor (F) VIIa inhibitor. BMS-593214 shows antithrombotic and antihaemostatic properties. BMS-593214 is a direct competitive inhibitor of human FVIIa and a non-competitive inhibitor of Viia-activated substrate FX. BMS-593214 prevents electroinduced carotid artery thrombosis (AT) and wire induced vena cava thrombosis (VT)[1].

  • CAS Number: 1004551-40-9
  • MF: C31H27N3O4
  • MW: 505.56400
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DACN(Tos2)

DACN(Tos2) is a a click chemistry reagent containing an cycloalkynes group. The alkyne moiety within the ring has a unique bent structure and high reactivity toward cycloaddition reactions. DACN(Tos2) through such strain-promoted azide-alkyne cycloadditions (SPAAC) using cycloalkynes. DACN(Tos2) can be used for the research of molecular conjugation[1].

  • CAS Number: 1797508-57-6
  • MF: C21H24N2O4S2
  • MW: 432.56
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

RABDOPHYLLIN G

Rabdosin C (Isodonoiol) is an ent-kaurane diterpenoidthat can be found in rubescens var. lushanensis. Rabdosin C shows cytotoxicity[1].

  • CAS Number: 82460-75-1
  • MF: C22H30O7
  • MW: 406.47
  • Catalog: Cancer
  • Density: 1.3g/cm3
  • Boiling Point: 600.8ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 207.5ºC

Isomorellic acid

Isomorellic acid is a cytotoxic caged xanthone and can be used for cancer research[1].

  • CAS Number: 5262-69-1
  • MF: C33H36O8
  • MW: 560.634
  • Catalog: Cancer
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 777.6±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 251.8±26.4 °C

21-O-Tigloylgymnemagenin

21-​O-​Tigloylgymnemagenin (Compound 7) is a acylated triterpenes isolated from Gymnema sylvestre[1].

  • CAS Number: 1581276-63-2
  • MF: C35H56O7
  • MW: 588.81494
  • Catalog: Others
  • Density: 1.20±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Methylumbelliferyl phosphate

4-methylumbelliferyl phosphate is a fluorogenic substrate of alkaline phosphatase.

  • CAS Number: 3368-04-5
  • MF: C10H9O6P
  • MW: 240.149
  • Catalog: Dye Reagents
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 513.6±60.0 °C at 760 mmHg
  • Melting Point: 215-218 °C
  • Flash Point: 264.4±32.9 °C

DAMNACANTHOL

Damnacanthol is a natural product that can be isolated from Damnacanthus major[1].

  • CAS Number: 477-83-8
  • MF: C16H12O5
  • MW: 284.26300
  • Catalog: Others
  • Density: 1.455g/cm3
  • Boiling Point: 527.5ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 202ºC

N-Boc-trans-4-N-Fmoc-amino-L-proline

(2S,4R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid is a proline derivative[1].

  • CAS Number: 176486-63-8
  • MF: C25H28N2O6
  • MW: 452.500
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 650.2±55.0 °C at 760 mmHg
  • Melting Point: 199ºC(lit.)
  • Flash Point: 347.0±31.5 °C

Laricitrin 3-O-glucoside

Laricitrin 3-O-glucoside is an antioxidant agent. Laricitrin 3-O-glucoside correlates significantly with DPPH assay and CUPRAC assay[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2',6'-Dihydroxy-3',4'-dimethoxychalcone

Pashanone is a compound isolated from Lindera erytbrocarpa Makino (Lauraceae)[1].

  • CAS Number: 42438-78-8
  • MF: C17H16O5
  • MW: 300.306
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 546.5±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 203.4±23.6 °C

Cloricromenehydrochloride

Cloricromen (Cloricromene) hydrochloride is a platelet aggregation inhibitor. Cloricromen hydrochloride can inhibit platelet aggregation in man and in experimental thrombosis[1].

  • CAS Number: 74697-28-2
  • MF: C20H27Cl2NO5
  • MW: 432.33800
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: 538ºC at 760 mmHg
  • Melting Point: 221-222.3ºC
  • Flash Point: 279.2ºC

FN-A208 fusion peptide

FN-A208 is a biological active peptide. (This peptide is a fusion of A208, derived from murine laminin a1, and the active site of fibronectin (GRGDS), with a glycine spacer. This peptide forms amyloid-like fibrils and promotes formation of actin stress fibers that mediate fibroblast cell attachment, offering it potential as a bioadhesive for tissue regeneration and engineering. FN-A208 interacts with IKVAV receptors and integrins. Its activity is disrupted by the presence of EDTA.)

  • CAS Number: 809281-07-0
  • MF: C69H121N25O26
  • MW: 1716.85
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CQ211

CQ211 is a potent and selective RIOK2 inhibitor with a Kd of 6.1 nM. CQ211 exhibits potent proliferation inhibition activity against multiple cancer cell lines[1].

  • CAS Number: 2648986-65-4
  • MF: C26H22F3N7O2
  • MW: 521.49
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Balanophonin

(±)-Balanophonin (compound 12) is a lignan first isolated from Otochilus fuscus[1].

  • CAS Number: 118916-57-7
  • MF: C20H20O6
  • MW: 356.369
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 552.5±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 197.0±23.6 °C

Veraguensin

Veraguensin is a lignan compound derived from Magnolia sp.. Veraguensin can inhibit bone resorption[1]

  • CAS Number: 19950-55-1
  • MF: C22H28O5
  • MW: 372.45500
  • Catalog: Others
  • Density: 1.082±0.06 g/cm3
  • Boiling Point: 479.1±45.0℃(Predicted)
  • Melting Point: 128.0-129.2 ºC (methanol)
  • Flash Point: N/A

7-Hydroxyquetiapine

7-Hydroxyquetiapine (ICI 214227) is the major active metabolite of antipsychotic medicine Quetiapine[1].

  • CAS Number: 139079-39-3
  • MF: C21H25N3O3S
  • MW: 399.50700
  • Catalog: Neurological Disease
  • Density: 1.33 g/cm3
  • Boiling Point: 612.4ºC at 760 mmHg
  • Melting Point: 56-60ºC
  • Flash Point: 324.2ºC

ALPHA-FUC-[1->2]-BETA-GAL-[1->4][ALPHA-FUC-(1->3)]-BETA-GLCNAC-[1->3]-BETA-GAL-[1->4]-GLC

LNnDFH I is a natural product that can be isolated from human urine[1].

  • CAS Number: 62469-99-2
  • MF: C38H65NO29
  • MW: 999.91
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-Oxodehydroabietic acid

7-Oxodehydroabietic acidis a diterpene resin acid isolated from the roots of the pine Pinus densiflora. 7-Oxodehydroabietic acid play a defensive role against herbivorous insects via insect endocrine-disrupting activity[1].

  • CAS Number: 18684-55-4
  • MF: C20H26O3
  • MW: 314.419
  • Catalog: Infection
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 475.4±45.0 °C at 760 mmHg
  • Melting Point: 90-91 °C
  • Flash Point: 255.4±25.2 °C

H-Glu(OMe)-OH

H-Glu(OMe)-OH is a glutamic acid derivative[1].

  • CAS Number: 1499-55-4
  • MF: C6H11NO4
  • MW: 161.156
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 316.1±37.0 °C at 760 mmHg
  • Melting Point: 182 °C (dec.)(lit.)
  • Flash Point: 145.0±26.5 °C

MIF098

MIF098 is a macrophage migration inhibitory factor (MIF) antagonist. MIF098 inhibits proliferation, migration and fibrosis of pulmonary smooth muscle cells. MIF098 can be used for immunoinflammation-related disease research[1].

  • CAS Number: 1208448-95-6
  • MF: C15H13NO3
  • MW: 255.27
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

LysoTracker Yellow HCK 123

LysoTracker Yellow HCK 123 is a potent yellow membrane-permeable fluorescent probe. LysoTracker Yellow HCK 123 is a weakly basic amine that selectively accumulates in cellular compartments with low luminal pH. (λex=465 nm, λem=535 nm)[1].

  • CAS Number: 1064123-31-4
  • MF: C16H24N6O4
  • MW: 364.40
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

16-Oxoalisol A

16-Oxoalisol A is a triterpene in Rhizoma Alismatis. Rhizoma Alismatis is a commonly used traditional Chinese medicine (TCM). Rhizoma Alismatis can be used for the research of urinary tract diseases[1].

  • CAS Number: 124515-98-6
  • MF: C30H48O6
  • MW: 504.698
  • Catalog: Metabolic Disease
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 666.4±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 370.8±28.0 °C

Pigment Violet 29

3,4,9,10-Perylenetetracarboxylic-diimide (PTCDI), an organic heteropolycyclic compound, is a dimethylimine that can be used in biological dyes and indicators[1].

  • CAS Number: 81-33-4
  • MF: C24H10N2O4
  • MW: 392.363
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 781.7±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 295.2±33.0 °C