Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

agrimonolide-6-O-glucopyranoside

Agrimonolide 6-O-β-D-glucoside is a isocoumarin that can be isolated from Agrimonia pilosa. Agrimonolide 6-O-β-D-glucoside is used in hepatic disease research[1].

  • CAS Number: 126223-29-8
  • MF: C24H28O10
  • MW: 476.47
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 807.7±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 277.7±27.8 °C

Tridecane

Tridecane is a short chain aliphatic hydrocarbon containing 13 carbon atoms. Tridecane is an volatile oil component isolated from essential oil of Piper aduncum L. Tridecane is a stress compound released by the brown marmorated stink bugs stress compound[1][2].

  • CAS Number: 629-50-5
  • MF: C13H28
  • MW: 184.36100
  • Catalog: Others
  • Density: 0.756 g/mL at 25 °C(lit.)
  • Boiling Point: 110-112 °C12 mm Hg(lit.)
  • Melting Point: −6-−4 °C(lit.)
  • Flash Point: 215 °F

Resolvin E2

Resolvin E2 ((-)-Resolvin E2), a proresolving lipid mediator, is useful as a lead for anti-inflammatory agent[1].

  • CAS Number: 865532-70-3
  • MF: C20H30O4
  • MW: 334.45000
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Methylumbelliferyl-β-D-glucuronide hydrate

4-Methylumbelliferyl-β-D-glucuronide hydrate is a fluorogenic substrat (λex=362 nm , λem=445 nm).

  • CAS Number: 881005-91-0
  • MF: C16H18O10
  • MW: 370.30800
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d58

1,2-Dimyristoyl-sn-glycero-3-phosphocholine-d58 is deuterium labeled 1,2-Dimyristoyl-sn-glycero-3-phosphocholine. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid used in liposomes. 1,2-Dimyristoyl-sn-glycero-3-phosphocholine

  • CAS Number: 326495-29-8
  • MF: C36H14D58NO8P
  • MW: 736.29
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Acacetin 7-O-β-sophoroside

Acacetin 7-O-β-sophoroside is a flavonoid glycoside isolated from the rhizomes and roots of valerian[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Morin monohydrate

Morin monohydrate, a plant-derived flavonoid, possesses low antioxidant activity. Morin is a fluorescing chelating agent used in aluminum speciation[1][2].

  • CAS Number: 6202-27-3
  • MF: C15H12O8
  • MW: 320.25100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hispolon

Hispolon, a polyphenol, can be isolated from Phellinus linteus. Hispolon possesses anticancer, antidiabetic, antioxidant, antiviral, hepatoprotective, anti-diabetic, and anti-inflammatory activities[1].

  • CAS Number: 173933-40-9
  • MF: C12H12O4
  • MW: 220.221
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 477.2±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 256.5±25.2 °C

SCH00013

SCH00013 is a cardiotonic agent that primarily acts via an increase in myofibrillar Ca++ sensitivity, have a significant Ca(2+)sensitizing effect at pH 7.2 to 7.4.In vitro: SCH00013 at 10-4 M increased the systolic cell shortening by 52% above the base-line value in association with an insignificant increase in the systolic fluorescence ratio by 15% above the control. [1]In vivo: The positive inotropic effects of 10?4 M SCH00013 on the dog and rabbit were 38% and 29% of the maximal response to isoproterenol. [1] CH00013 elicited a positive inotropic effect at more than 0.3 and 1 mg/kg, i.v. in normal and heart failure dogs. [2] SCH00013 elicits a positive inotropic effect mainly through an increase in myofilament Ca2+ sensitivity without increasing the heart rate. [3]

  • CAS Number: 217963-18-3
  • MF: C18H20N4O2
  • MW: 324.377
  • Catalog: Cardiovascular Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Trp-OH-13C11,15N2

Fmoc-Trp-OH-13C11,15N2 is a 15N-labeled and 13C-labled Fmoc-Pro-OH[1].

  • CAS Number: 2483830-20-0
  • MF: C1513C11H2215N2O4
  • MW: 439.37
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

9-O-Methylstecepharine

9-O-Methylstecepharine (compound 7) is an alkaloid that can be found in Stephania cepharantha[1].

  • CAS Number: 267007-51-2
  • MF: C22H28ClNO9
  • MW: 485.91
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,6-Dichlorobiphenyl-2′,3′,4′,5′,6′-d5

2,6-Dichlorobiphenyl-2′,3′,4′,5′,6′-d5 is the deuterium labeled 2,6-Dichloro-1,1'-biphenyl[1].

  • CAS Number: 1276197-38-6
  • MF: C12H3D5Cl2
  • MW: 228.13
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

GLUT4 activator 1

GLUT4 activator 1 (Compound 26b) is a potent glucose transporter type 4 (GLUT4) translocation activator with an EC50 of 0.14 μM[1].

  • CAS Number: 2253733-37-6
  • MF: C23H21FN4O3S
  • MW: 452.50
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Diastase

Amylase is an enzyme produced by pancreas and salivary glands, catalyzing the hydrolysis of starch into sugars.

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

B8R 20-27

B8R 20-27 is a biological active peptide. (This is amino acids 20 to 27 fragment of B8R, a vaccinia virus (VV) gene that encodes a secreted protein related to gamma interferon receptor. B8R binding to IFN-g neutralizes its antiviral activity.)

  • CAS Number: 848642-31-9
  • MF: C44H65N9O15
  • MW: 960.04
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Gnetumontanin B

Gnetumontanin B is a stilbenoid that can be found in Gnetum montanum f. megalocarpum. Gnetumontanin B inhibits TNF-α production with an IC50 value of 1.49 µM[1].

  • CAS Number: 809237-87-4
  • MF: C42H32O11
  • MW: 712.697
  • Catalog: Inflammation/Immunology
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 857.5±65.0 °C at 760 mmHg
  • Melting Point: 209-210 °C
  • Flash Point: 472.4±34.3 °C

Carcinoembryonic Antigen CEA

Carcinoembryonic antigen (CEA) is a tumor marker in lung cancer.

  • CAS Number: 168635-85-6
  • MF: C43H68N10O15
  • MW: 965.08
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

EA2

EA2 is a biological active peptide. (This is a peptide substrate for polypeptide N-acetylgalactosaminyltransferase (polypeptide GalNAc-T).)

  • CAS Number: 562082-63-7
  • MF: C55H92N14O23
  • MW: 1317.40
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-BENZYLOXYBENZALDEHYDE-α-D1

3-Benzyloxybenzaldehyde-α-d1 is the deuterium labeled 3-Benzyloxybenzaldehyde[1].

  • CAS Number: 1219805-34-1
  • MF: C14H11DO2
  • MW: 213.25000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Naphthalene-2,6-dicarboxylic acid-d6

Naphthalene-2,6-dicarboxylic acid-d6 is the deuterium labeled Naphthalene-2,6-dicarboxylic acid[1].

  • CAS Number: 682321-46-6
  • MF: C12H2D6O4
  • MW: 222.23
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-L-norvaline

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)pentanoic acid is a valine derivative[1].

  • CAS Number: 135112-28-6
  • MF: C20H21NO4
  • MW: 339.385
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 557.9±33.0 °C at 760 mmHg
  • Melting Point: 151-153ºC
  • Flash Point: 291.2±25.4 °C

N-[4-(2-Pyridinyl)benzoyl]glycine-13C2,15N

N-[4-(2-Pyridinyl)benzoyl]glycine-13C2,15N is a 15N-labeled and 13C-labled labeled N-[4-(2-Pyridinyl)benzoyl]glycine[1].

  • CAS Number: 1391053-26-1
  • MF: C1213C2H12N15NO3
  • MW: 259.24
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ribocil-C

Ribocil-C is a highly selective inhibitor of bacterial riboflavin riboswitches.

  • CAS Number: 1825355-56-3
  • MF: C21H21N7OS
  • MW: 419.503
  • Catalog: Infection
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 672.0±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 360.2±34.3 °C

(R)-3-((TERT-BUTOXYCARBONYL)AMINO)-3-(O-TOLYL)PROPANOIC ACID

(R)-Boc-2-methyl-β-Phe-OH is a phenylalanine derivative[1].

  • CAS Number: 500770-86-5
  • MF: C15H21NO4
  • MW: 279.332
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 439.4±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 219.5±27.3 °C

Isosorbide-2-mononitrate-13C6

Isosorbide-2-mononitrate-13C6 is the 13C labeled Isosorbide-2-mononitrate[1].

  • CAS Number: 1391051-97-0
  • MF: 13C6H9NO6
  • MW: 197.09
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Influenza virus NP (44-52)

Influenza virus NP (44-52) is a biological active peptide. (HLA-A*01 restricted epitope from influenza virus nucleoprotein (44-52).)

  • CAS Number: 152647-27-3
  • MF: C46H74N10O17S
  • MW: 1071.20
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

GPVI antagonist 1

GPVI antagonist 1 (compound 5) is a glycoprotein VI (GPVI) platelet receptor antagonist. GPVI antagonist 1 inhibits collagen-induced platelet aggregation with an IC50 of 25.3 μM[1].

  • CAS Number: 1327156-14-8
  • MF: C19H19N3O4S
  • MW: 385.44
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Cbz-DL-proline

Z-DL-Pro-OH (N-Cbz-DL-proline) is a proline derivative, can be used for the synthesis of drugs or other compounds[1].

  • CAS Number: 5618-96-2
  • MF: C13H15NO4
  • MW: 249.262
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 432.3±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 215.3±28.7 °C

Ataprost

Ataprost (ONO 41483) is an orally active Carboprostacyclin (HY-112322) analogue. Ataprost exhibits 2.6 times more active than Carboprostacyclin in inhibiting ADP-induced platelet aggregation in vitro. Ataprost has the ability to relieve coronary spasm[1].

  • CAS Number: 83997-19-7
  • MF: C21H32O4
  • MW: 348.47600
  • Catalog: Cardiovascular Disease
  • Density: 1.255g/cm3
  • Boiling Point: 529.8ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 288.3ºC

MAGE-3 Antigen (167-176) (human) acetate salt

MAGE-3 Antigen (167-176) (human) is a polypeptide containing eight amino acids. MAGE-3 Antigen (167-176) (human) is a human leukocyte antigen HLA-B44 molecules epitope encoded by melanoma antigen gene (MAGE)[1].

  • CAS Number: 178243-46-4
  • MF: C53H80N12O16S
  • MW: 1173.338
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 1588.6±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 914.6±34.3 °C