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2648986-65-4

2648986-65-4 structure
2648986-65-4 structure
  • Name: CQ211
  • Chemical Name: CQ211
  • CAS Number: 2648986-65-4
  • Molecular Formula: C26H22F3N7O2
  • Molecular Weight: 521.49
  • Catalog: Research Areas Cancer
  • Create Date: 2022-07-11 23:20:52
  • Modify Date: 2025-08-25 16:25:29
  • CQ211 is a potent and selective RIOK2 inhibitor with a Kd of 6.1 nM. CQ211 exhibits potent proliferation inhibition activity against multiple cancer cell lines[1].

Name CQ211
Description CQ211 is a potent and selective RIOK2 inhibitor with a Kd of 6.1 nM. CQ211 exhibits potent proliferation inhibition activity against multiple cancer cell lines[1].
Related Catalog
Target

Kd: 6.1 nM (RIOK2)[1]

In Vivo CQ211 (25 mg/kg) inhibits the tumor progression with tumor growth inhibition (TGI) of 30.9% in rats[1].
References

[1]. Ouyang Y, et al. Discovery of 8-(6-Methoxypyridin-3-yl)-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)-1,5-dihydro-4H-[1,2,3]triazolo[4,5-c]quinolin-4-one (CQ211) as a Highly Potent and Selective RIOK2 Inhibitor. J Med Chem. 2022 Jun 9;65(11):7833-7842.

Molecular Formula C26H22F3N7O2
Molecular Weight 521.49
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