Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

bacteriopheophytin

Bacteriopheophytin, a photosynthetic pigment, is a bacterial demagnetised chlorophyll composed of bacterial chlorophyll in which two hydrogen atoms replace the magnesium center. Bacteriopheophytin acts as an electron acceptor in the purple bacterial reaction center (RC) and is involved in electron transfer[1].

  • CAS Number: 17453-58-6
  • MF: C55H76N4O6
  • MW: 889.21500
  • Catalog: Others
  • Density: 1.095g/cm3
  • Boiling Point: 997.8ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 557.2ºC

ATTO 550

ATTO 550 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 554/576 nm.

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

11-Deoxymogroside V

11-Deoxymogroside V is a cucurbitane triterpene glycoside[1].

  • CAS Number: 1707161-17-8
  • MF: C60H102O28
  • MW: 1271.435
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Amitrole-13C,15N2

Amitrole-13C,15N2is the deuterium labeled4H-1,2,4-Triazol-3-amine(HY-W110148)[1].

  • CAS Number: 1346603-92-6
  • MF: C13CH4N215N2
  • MW: 87.06
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(22R)-2β,3β,20,22,25-Pentahydroxy-5β-cholesta-8,14-dien-6-one

Podecdysone B is a phytoecdysone isolated from Cyanotis arachnoidea[1].

  • CAS Number: 22612-27-7
  • MF: C27H42O6
  • MW: 462.61900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(4R)-1-Methyl-4-propyl-L-proline methyl ester-d3

(4R)-1-Methyl-4-propyl-L-proline methyl ester-d3 is the deuterium labeled (4R)-1-Methyl-4-propyl-L-proline methyl ester[1].

  • CAS Number: 1356837-90-5
  • MF: C10H16D3NO2
  • MW: 188.28
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Borax

Sodium tetraborate decahydrate can be used as an excipient, such as preservative, mordant. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

  • CAS Number: 1303-96-4
  • MF: B4H20Na2O17
  • MW: 381.37
  • Catalog: Others
  • Density: 1.73 g/mL at 25 °C(lit.)
  • Boiling Point: 320°C
  • Melting Point: 75 °C
  • Flash Point: N/A

3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid

2-O-β-D-Glucosyloxy-4-methoxybenzene propanoic acid is a glucoside derivative[1].

  • CAS Number: 477873-63-5
  • MF: C16H22O9
  • MW: 358.34
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 624.6±55.0 °C at 760 mmHg
  • Melting Point: 168-169℃ (acetone )
  • Flash Point: 228.0±25.0 °C

MRS1177

MRS1177 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 0.3 nM.

  • CAS Number: 183721-13-3
  • MF: C20H12ClN5O2
  • MW: 389.79
  • Catalog: Adenosine Receptor
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Myricetin-3-O-rutinoside

Myricetin-3-O-rutinoside (Compound 3) is a natural product that can be isolated from Picea abies[1].

  • CAS Number: 41093-68-9
  • MF: C27H30O17
  • MW: 626.52
  • Catalog: Others
  • Density: 1.89±0.1 g/cm3(Predicted)
  • Boiling Point: 1053.4±65.0 °C(Predicted)
  • Melting Point: 190-192 °C
  • Flash Point: N/A

6H-Dibenzo[b,d]pyran-6-one

3,4-Benzocoumarin is a kind of the expanded structure of coumarin derivatives.Coumarin is a chemical compound in the benzopyrone chemical class that can be found in many natural species. Coumarins possess variety of biological activities and unique photophysical properties[1]. 3,4-Benzocoumarin, a AOH‐like compound , has the sensibility of the antibody with an IC50 of 919.2 ng/mL[2].

  • CAS Number: 2005-10-9
  • MF: C13H8O2
  • MW: 196.20100
  • Catalog: Others
  • Density: 1.277g/cm3
  • Boiling Point: 354.7ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 148ºC

PL-3994

PL-3994 is a natriuretic peptide receptor-A (NPR-A) agonist that is resistant to neutral endopeptidase and acts as a bronchodilator. PL-3994 produces concentration-dependent relaxation of pre-contracted guinea-pig trachea with an IC50 value of 42.7 nM[1].

  • CAS Number: 952295-80-6
  • MF: C82H127N27O20S2
  • MW: 1875.18
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

25-O-methylcimigenol-3-O-beta-D-xylopyranoside

25-O-Methylcimigenol-3-O-D-xylopyranoside is an active compound. 25-O-Methylcimigenol-3-O-D-xylopyranoside can be used for the research of various biochemical [1].

  • CAS Number: 27994-13-4
  • MF: C36H58O9
  • MW: 634.840
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 730.2±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 395.4±32.9 °C

Fmoc-Homoser(Trt)-OH

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-trityl-L-homoserine is a serine derivative[1].

  • CAS Number: 111061-55-3
  • MF: C38H33NO5
  • MW: 583.67200
  • Catalog: Others
  • Density: 1.242g/cm3
  • Boiling Point: 767.5ºC at 760 mmHg
  • Melting Point: 63-66 °C
  • Flash Point: 418ºC

Uridine, 6-methyl-

6-Methyluridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].

  • CAS Number: 16710-13-7
  • MF: C10H14N2O6
  • MW: 258.23
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: 1.576g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

MESO-TETRA(4-N,N,N-TRIMETHYLANILINIUM) PORPHINE TETRACHLORIDE

meso-Tetra(4-N,N,N-trimethylanilinium) porphine tetrachloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 92739-64-5
  • MF: C56H62Cl4N8
  • MW: 988.96
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

A-769662

A-769662 is a potent, reversible AMPK activator with EC50 of 0.8 μM.

  • CAS Number: 844499-71-4
  • MF: C20H12N2O3S
  • MW: 360.386
  • Catalog: AMPK
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 630.1±55.0 °C at 760 mmHg
  • Melting Point: 268.39° C
  • Flash Point: 334.9±31.5 °C

Atto 425-NHS ester

ATTO 425 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 425 NHS ester is an NHS ester derivative of ATTO 425 that can be used to label proteins or antibodies.

  • CAS Number: 892156-28-4
  • MF: C26H30N2O8
  • MW: 498.52500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ac-Lys-Ome HCl

Methyl acetyl-L-lysinate hydrochloride is a lysine derivative[1].

  • CAS Number: 20911-93-7
  • MF: C9H19ClN2O3
  • MW: 238.712
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 354.6ºC at 760mmHg
  • Melting Point: 108-114ºC(lit.)
  • Flash Point: 168.2ºC

3,3'-Dioctadecyloxacarbocyanine perchlorate

3,3′-Dioctadecyloxacarbocyanine perchlorate is a green fluorescent lipophilic tracer, which is weakly fluorescent in water but highly fluorescent and quite photostable when incorporated into membranes.

  • CAS Number: 34215-57-1
  • MF: C53H85ClN2O6
  • MW: 881.70500
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Soporidine

Soporidine is an antagonist of germination of the parasitic plant Striga hermonthica. Soporidine specifically inhibits a S. hermonthica strigolactone receptor and inhibits the parasite's germination[1].

  • CAS Number: 1060376-43-3
  • MF: C27H30F3NO3
  • MW: 473.53
  • Catalog: Others
  • Density: 1.24±0.1 g/cm3
  • Boiling Point: 537.7±50.0 °C
  • Melting Point: N/A
  • Flash Point: N/A

Hexacosyl (E)-ferulate

Hexacosyl (E)-ferulate (n-Hexacosyl trans-ferulate) is an antioxidant agent that displays significant antioxidant activity in the DPPH (HY-112053) assay with the RC50 (50% reduction concentration) of 0.0976 mg/mL[1].

  • CAS Number: 63034-29-7
  • MF: C36H62O4
  • MW: 558.88
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 638.7±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 184.1±20.8 °C

N-(2,6-Dimethylphenyl)-1-isopropylpiperidine-2-carboxamide-d7

N-(2,6-Dimethylphenyl)-1-isopropylpiperidine-2-carboxamide-d7 is the deuterium labeled N-(2,6-dimethylphenyl)-1-isopropylpiperidine-2-carboxamide[1].

  • CAS Number: 1276197-11-5
  • MF: C17H19D7N2O
  • MW: 281.44
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Valylglutamic acid

Valylglutamic acid is a biologically active peptide.

  • CAS Number: 3062-07-5
  • MF: C10H18N2O5
  • MW: 246.26000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

His 11

His11 is consists of a contiguous series of amino acid residues. His11 can be used as a tag peptide[1].

  • CAS Number: 620927-23-3
  • MF: C66H79N33O12
  • MW: 1526.55
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Condurango glycoside A0

Condurango glycoside A0 is a pregnane ester glycoside that can be isolated from Marsdema cundurango[1].

  • CAS Number: 115810-21-4
  • MF: C59H88O22
  • MW: 1149.32
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Obtusalin

Obtusalin is a triterpenoid found in R. dauricum for the first time and shows UV absorption at 210 nm. Obtusalin has some antibacterial activity[1][2].

  • CAS Number: 125164-64-9
  • MF: C30H50O2
  • MW: 442.73
  • Catalog: Bacterial
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-Nitro BAPTA tetramethyl ester

5-Nitro BAPTA tetramethyl ester is a calcium chelator. 5-Nitro BAPTA tetramethyl ester involves in the two-photon probe synthesis, and is used for real-time imaging of intracellular calcium ions, calcium waves monitoring at a depth of 100-300 μm in liver tissues for 1100-4000 s. 5-Nitro BAPTA tetramethyl ester, together with fluorescent compound 2-Me-substituted TM, can be used to form a red fluorescent probe (CaTM-2 AM)[1][2].

  • CAS Number: 172646-43-4
  • MF: C26H31N3O12
  • MW: 577.53700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BODIPY FL thalidomide

BODIPY FL thalidomide is a high-affinity fluorescent probe for the human cereblon protein with a Kd value of 3.6 nM[1]

  • CAS Number: 2740620-18-0
  • MF: C37H43BF2N6O7
  • MW: 732.58
  • Catalog: Ligand for E3 Ligase
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TP748

TP748,an isoxazole, is a key intermediate for fully synthetic tetracyclines[1].

  • CAS Number: 951698-15-0
  • MF: C15H18N2O2
  • MW: 258.316
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 367.3±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 176.0±27.9 °C