Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

BDP TMR alkyne

BDP TMR alkyne is an alkyne-containing click chemistry reagent that can click chemistry with azides. BDP TMR alkyne has the fluorophore BDP and can be used for oligonucleotide labeling and amino acid sequencing.

  • CAS Number: 2006345-32-8
  • MF: C24H24BF2N3O2
  • MW: 435.28
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Hexyl-N,N-dimethyl-1-octanaminium bromide

Hexyldimethyloctylammonium Bromide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 187731-26-6
  • MF: C16H36BrN
  • MW: 322.368
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Octahydrocurcumin

Octahydrocurcumin is a hydrogenated derivatives of curcumin; metabolite of curcumin.IC50 value:Target: OKT3-induced PBMC proliferation was inhibited by octahydrocurcumin with IC50 of 82 uM. The investigated substances with the strongest effect on radical scavenging were tetrahydro-, hexahydro-, and octahydrocurcumin with IC50 values of 10.0, 11.7, and 12.3 microM, respectively [1]. curcumin and tetrahydrocurcumin significantly inhibited the release of prominent cytokines, including tumor necrosis factor?α (TNF?α) and interleukin?6 (IL?6); however, hexahydrocurcumin and octahydrocurcumin did not significantly alter cytokine release [2]. Hydrogenated derivatives of curcumin exhibited stronger DPPH scavenging activity compared to curcumin and a reference antioxidant, trolox. The scavenging activity significantly decreased in the order THC>HHC=OHC>trolox>curcumin>Dmc>>>Bdmc [3].

  • CAS Number: 36062-07-4
  • MF: C21H28O6
  • MW: 376.443
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 623.5±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 330.9±31.5 °C

4-O-beta-Glucopyranosyl-cis-couMaric acid

4-O-beta-Glucopyranosyl-cis-coumaric acid is a natural compound isolated formn Nelumbo nucifera Gaertn.

  • CAS Number: 117405-48-8
  • MF: C15H18O8
  • MW: 326.29862
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 631.4±55.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A
  • CAS Number: 2411590-92-4
  • MF: C13H27NO4Si
  • MW: 289.44
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Gly-OBzl.TsOH

H-Gly-OBzl.TosOH is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 1738-76-7
  • MF: C16H19NO5S
  • MW: 337.391
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 245.5ºC at 760 mmHg
  • Melting Point: 132-134 °C
  • Flash Point: 110.3ºC

Negsehisandrin G

Angeloyl-(+)-gomisin K3 is a dibenzocyclooctane lignan[1].

  • CAS Number: 1023744-69-5
  • MF: C28H36O7
  • MW: 484.581
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 625.8±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 264.5±31.5 °C

6-Methyl-5-azacytidine

6-Methyl-5-azacytidine is a potent DNMT inhibitor.

  • CAS Number: 105330-94-7
  • MF: C9H14N4O5
  • MW: 258.23
  • Catalog: DNA Methyltransferase
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Albendazole sulfoxide D3

Albendazole sulfoxide D3 is deuterium labeled Albendazole sulfoxide, which is a broad-spectrum anthelmintic.

  • CAS Number: 1448346-38-0
  • MF: C12H12D3N3O3S
  • MW: 284.349
  • Catalog: Parasite
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Atractyloside A

Atractyloside A(126054-77-1) is a natural TCM reference compound.

  • CAS Number: 126054-77-1
  • MF: C21H36O10
  • MW: 448.504
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 684.8±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 234.1±25.0 °C

FIN 56

FIN56 is a specific inducer of ferroptosis.

  • CAS Number: 1083162-61-1
  • MF: C25H31N3O5S2
  • MW: 517.66
  • Catalog: Ferroptosis
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tetrachlorohydroquinone

Tetrachlorohydroquinone (TCHQ) is a metabolite of pentachlorophenol. Tetrachlorohydroquinone increases DNA lesions and induce oxidative stress in rodents[1].

  • CAS Number: 87-87-6
  • MF: C6H2Cl4O2
  • MW: 247.89
  • Catalog: Bacterial
  • Density: 1.848 g/cm3
  • Boiling Point: 286.2ºC
  • Melting Point: 238-240 °C
  • Flash Point: 126.9ºC

Ethyl nonanoate

Ethyl nonanoate is a rich ester in spirits and its presence is commonly related to the pleasant fruity bouquet of alcoholic beverages. Ethyl nonanoate is an endogenous metabolite[1].

  • CAS Number: 123-29-5
  • MF: C11H22O2
  • MW: 186.291
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 220.0±0.0 °C at 760 mmHg
  • Melting Point: -44°C
  • Flash Point: 94.4±0.0 °C

I-bu-rG Phosphoramidite

I-bu-rG Phosphoramidite is a phosphinamide monomer which can be used in the synthesis of nucleotides and nucleic acids.

  • CAS Number: 147201-04-5
  • MF: C50H68N7O9PSi
  • MW: 970.176
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N6-Cbz-L-Lysine benzyl ester hydrochloride

N6-Carbobenzoxy-L-lysine benzyl ester hydrochloride is a lysine derivative[1].

  • CAS Number: 6366-70-7
  • MF: C21H27ClN2O4
  • MW: 406.903
  • Catalog: Others
  • Density: 1.163g/cm3
  • Boiling Point: 511.7ºC at 760 mmHg
  • Melting Point: 138-140ºC
  • Flash Point: 263.2ºC

H-Glu-Tyr-OH

H-Glu-Tyr-OH is adipeptide.

  • CAS Number: 3422-39-7
  • MF: C14H18N2O6
  • MW: 310.30
  • Catalog: Others
  • Density: 1.414 g/cm3
  • Boiling Point: 692.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 372.3ºC

UNII:841B886EJ7

DPPG sodium (1,2-Dipalmitoyl-sn-glycero-3-PG sodium) is a phospholipid containing the long-chain(16:0) palmitic acid inserted at the sn-1 and sn-2 positions. DPPG sodium is used in the generation of micelles, liposomes and other types of artificial membranes[1].

  • CAS Number: 200880-41-7
  • MF: C38H74NaO10P
  • MW: 744.952
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TIC10 Analogue

TIC10 isomer is the isomer of TIC10. TIC10 isomer does not possess the reported biological activity of inducing TRIAL expression.

  • CAS Number: 41276-02-2
  • MF: C24H26N4O
  • MW: 386.489
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 559.7±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 292.3±32.9 °C

Neoagarohexaitol

Neoagarohexaitol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 68289-59-8
  • MF: C36H58O28
  • MW: 938.82900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

8-Allyloxyadenosine

8-Allyloxyadenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

  • CAS Number: 2095417-69-7
  • MF: C13H17N5O5
  • MW: 323.30
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

16β-Hydroperoxyalisol B 23-acetate

16β-Hydroperoxyalisol B 23-acetate is a natural product that can be isolated from Alisma orientale[1].

  • CAS Number: 2221029-54-3
  • MF: C32H50O7
  • MW: 546.74
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3β-Acetoxyurs-11-en-28,13β-olide

3-Acetoxy-11-ursen-28,13-olide (11,12-dehydroursolic lactone acetate) is a reduction product of 11-ketoursolic acid[1].

  • CAS Number: 35959-08-1
  • MF: C32H48O4
  • MW: 496.721
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 572.8±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 278.2±28.5 °C

5-Methyluridine-2′-13C

5-Methyluridine-2′-13C is the 13C labeled 5-Methyluridine. 5-Methyluridine is a is an endogenous methylated nucleoside found in human flu[1][2].

  • CAS Number: 478510-98-4
  • MF: C10H14N2O6
  • MW: 259.22100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

disilicic acid

Cristobalite can be used as an excipient, such as disintegrants, anti-adhesives, glidants, suspending agents, thickeners, defoamers. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

  • CAS Number: 14464-46-1
  • MF: O2Si
  • MW: 60.08
  • Catalog: Others
  • Density: 2.6 g/mL at 25ºC(lit.)
  • Boiling Point: 4046 deg F
  • Melting Point: 3110 deg FºC
  • Flash Point: N/A

β-Cyclocitral

β-Cyclocitral, a volatile oxidized derivative of β-carotene, is a grazer defence signal unique to the Cyanobacterium Microcystis. β-Cyclocitral, one of the predominant volatile terpenoid compounds, can upregulate the expression of defence genes to enhance excess light (EL) acclimation. β-Cyclocitral is a powerful repellent[1][2][3].

  • CAS Number: 432-25-7
  • MF: C10H16O
  • MW: 152.23300
  • Catalog: Others
  • Density: 0.947g/cm3
  • Boiling Point: 212.1ºC at 760mmHg
  • Melting Point: 62-63ºC
  • Flash Point: 76.9ºC

2-Iodomelatonin

2-Iodomelatonin is a potent agonist of melatonin receptor 1 (MT1) with a Ki value of 28 pM, it is more 5-fold selective for MT1  over MT2[1]. 2-iodomelatonin can be used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues[1].

  • CAS Number: 93515-00-5
  • MF: C13H15IN2O2
  • MW: 358.17500
  • Catalog: Melatonin Receptor
  • Density: 1.63g/cm3
  • Boiling Point: 574.5ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 301.3ºC

N-PHTHALOYL-DL-METHIONINE

N-Phthaloyl-DL-methionine is a Methionine (HY-13694) derivative[1].

  • CAS Number: 52881-96-6
  • MF: C13H13NO4S
  • MW: 279.31200
  • Catalog: Others
  • Density: 1.422g/cm3
  • Boiling Point: 492ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 251.4ºC

Idetrexed

Idetrexed is a thymidylate synthase inhibitor specifically transported into alpha-folate receptor (alpha-FR)-overexpressing tumors. BGC 945 inhibited thymidylate synthase with a Ki of 1.2 nmol/L[1][2].

  • CAS Number: 501332-69-0
  • MF: C32H33N5O10
  • MW: 647.63
  • Catalog: Thymidylate Synthase
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tetrapropylammonium chloride

Tetrapropylammonium chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 5810-42-4
  • MF: C12H28ClN
  • MW: 221.810
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 240-242 °C(lit.)
  • Flash Point: N/A

Cedrusin

Cedrusin is a benzofuran derivative that can be isolated from Styrax suberifolius[1].

  • CAS Number: 75775-36-9
  • MF: C19H22O6
  • MW: 346.37
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 558.1±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 291.3±30.1 °C