Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

4-(1-Phenylethyl)resorcin

Phenylethyl resorcinol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 85-27-8
  • MF: C14H14O2
  • MW: 214.260
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 365.1±17.0 °C at 760 mmHg
  • Melting Point: 81 °C
  • Flash Point: 175.2±15.5 °C

Oleoside

Oleoside can be isolated from olive pomace[1].

  • CAS Number: 178600-68-5
  • MF: C16H22O11
  • MW: 390.339
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 707.5±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 256.8±26.4 °C

5-Methyluridine-5′-13C

5-Methyluridine-5′-13C is the 13C labeled 5-Methyluridine. 5-Methyluridine is a is an endogenous methylated nucleoside found in human flu[1][2].

  • CAS Number: 478511-02-3
  • MF: C10H14N2O6
  • MW: 259.22100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-Furan-2-yl-2’-O-methyl uridine

5-Furan-2-yl-2’-O-methyl uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 2095417-32-4
  • MF: C14H16N2O7
  • MW: 324.29
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Trimethoprim propanoic acid

Trimethoprim propanoic acid is a hapten.

  • CAS Number: 94236-24-5
  • MF: C17H22N4O5
  • MW: 362.38
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tetrazolium blue

Blue Tetrazolium (Tetrazolium blue), as a blue dye for microbial research, can be reduced into blue tetrazolium formazan (BTF). Blue Tetrazolium can be used to determine the activity of succinate dehydrogenase (SDH) in yeast strains, which has been reduced as a substrate. Use DMSO to extract BTF from cells, and test absorption spectrum of BTF. The BTF shows a wide wavelength range of 480-600 nm with maximal absorbance seen at 540 nm. Blue Tetrazolium, combines with succinate dehydrogenase (SDH)[1].

  • CAS Number: 1871-22-3
  • MF: C40H32Cl2N8O2
  • MW: 727.641
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 255 °C (dec.)(lit.)
  • Flash Point: N/A

CY5-SE triethylamine salt

Cy5-SE (Cy5 NHS Ester) triethylamine salt is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. Cy5-SE triethylamine salt is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides Ex=649 nm; Em=670 nm)[1].

  • CAS Number: 1497420-70-8
  • MF: C43H58N4O10S2
  • MW: 855.071
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

L-Leucyl-2-naphthylaMide hydrochloride

L-Leucine β-naphthylamide (hydrochloride) is a leucine derivative[1].

  • CAS Number: 893-36-7
  • MF: C16H21ClN2O
  • MW: 292.80400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 467ºC at 760 mmHg
  • Melting Point: 255-260 °C (dec.)
  • Flash Point: 236.2ºC

Imidazole

Imidazole is a planar 5-membered ring. Imidazole is a highly polar compound. Imidazole has been used extensively as a corrosion inhibitor.Imidazole is incorporated into many important biological molecules. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Imidazole is useful as a buffer in the pH range of 6.2-7.8 One of the applications of imidazole is in the purification of His-tagged proteins in immobilised metal affinity chromatography(IMAC). Imidazole is used to elute tagged proteins bound to Ni ions attached to the surface of beads in the chromatography column. An excess of imidazole is passed through the column, which displaces the His-tag from nickel co-ordination, freeing the His-tagged proteins. Imidazole has become an important part of many pharmaceuticals. Synthetic imidazoles are present in many fungicides and antifungal, antiprotozoal, and antihypertensive medications. Imidazole is part of the theophylline molecule, found in tea leaves and coffee beans, which stimulates the central nervous system. It is present in the anticancer medication mercaptopurine, which combats leukemia by interfering with DNA activities.

  • CAS Number: 288-32-4
  • MF: C3H4N2
  • MW: 68.077
  • Catalog: Biochemical Assay Reagents
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 257.0±9.0 °C at 760 mmHg
  • Melting Point: 88-91 °C(lit.)
  • Flash Point: 145.0±0.0 °C

D-glycero-D-manno-Heptitol

Volemitol (D-Volemitol) is a seven-carbon sugar alcohol that fulfills several important physiological functions in certain species of the genus Primula. Volemitol is the major nonstructural carbohydrate in leaves of all stages of development. Volemitol functions as a photosynthetic product, phloem translocate (phloem-mobile), and storage carbohydrate.Volemitol biosynthesis proceeds by a novel, NADPH-dependent, ketose reductase (sedoheptulose reductase)[1].

  • CAS Number: 488-38-0
  • MF: C7H16O7
  • MW: 212.19800
  • Catalog: Others
  • Density: 1.549g/cm3
  • Boiling Point: 558.3ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 291.5ºC

2-(Dimethylamino)acetaldehyde hydrochloride

2-(Dimethylamino)acetaldehyde hydrochloride can be used to synthesis Muscarine analogues[1].

  • CAS Number: 125969-54-2
  • MF: C4H10ClNO
  • MW: 123.581
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-[hydroxy-(3,4,5-trihydroxyoxan-2-yl)oxy-phosphoryl]oxy-phosphinic acid

UDP-xylose is a natural product that could be isolated from Cryptococcus laurentii (NRRL Y-1401). UDP-xylose is a sugar donor for the synthesis of glycoproteins, polysaccharides, various metabolites, and oligosaccharides in plants, vertebrates, and fungi[1][2].

  • CAS Number: 3616-06-6
  • MF: C14H22N2O16P2
  • MW: 536.27600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(3β,20E)-24-Norchola-5,20(22)-diene-3,23-diol

(3β,20E)-24-Norchola-5,20(22)-diene-3,23-diol is a steroid-based allylic alcohol.

  • CAS Number: 53495-21-9
  • MF: C23H36O2
  • MW: 344.53
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-(N,N-Dimethylmyristylammonio)propanesulfonate

3-(N,N-Dimethylmyristylammonio)propanesulfonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 14933-09-6
  • MF: C19H41NO3S
  • MW: 363.599
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 250ºC
  • Flash Point: >110ºC

Hexaflumuron

Hexazinone is a nonselective herbicide from the triazine family. Hexazinone binds to the D-1 quinone protein of the electron transport chain in photosystem II to inhibit the photosynthesis[1].

  • CAS Number: 86479-06-3
  • MF: C16H8Cl2F6N2O3
  • MW: 461.143
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 202-205ºC
  • Flash Point: N/A

Carboxylesterase-IN-1

Carboxylesterase-IN-1, a novel pesticide, exhibits inhibitory action on carboxylesterase at 50 μg/mL similar to the known inhibitor triphenyl phosphate.

  • CAS Number: 2609018-59-7
  • MF: C30H37BrN2O5
  • MW: 585.53
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Enocyanin

Enocyanin is an anthocyanin extracted from grapes. Enocyanin shows inhibitory effect on the leucine aminopeptidase, acid phosphatase, γ-glutamyl transpeptidase and esterase activity[1].

  • CAS Number: 11029-12-2
  • MF: C15H11O
  • MW: 207.247
  • Catalog: Phosphatase
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tanfanercept

Tanfanercept (HL036337) is an anti-TNF-α monoclonal antibody. Tanfanercept is effective in ameliorating corneal erosions in a dry eye (DE) mouse model[1][2].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,4-Dichlorobenzoic acid-d3

2,4-Dichlorobenzoic acid-d3 is the deuterium labeled 2,4-Dichlorobenzoic acid[1].

  • CAS Number: 1398065-99-0
  • MF: C7HD3Cl2O2
  • MW: 194.03
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

HIV-2 Peptide acetate salt

HIV-2 Peptide is a biologically active peptide.

  • CAS Number: 172486-63-4
  • MF: C93H140N30O28S2
  • MW: 2190.45
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

D-MoDE-A (1)

D-MoDE-A (1) is a bifunctional small molecule that mediates the degradation of extracellular proteins through the asialoglycoprotein receptor (ASGPR).

  • CAS Number: 2378837-67-1
  • MF: C71H121N11O39
  • MW: 1752.77
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(3S,5S)-Atorvastatin (sodium salt)

(3S,5S)-Atorvastatin sodium salt is a pregnane X receptor (PXR) activator and the inactive enantiomer of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor with lipid-lowering capabilities[1].

  • CAS Number: 1428118-38-0
  • MF: C33H34FN2NaO5
  • MW: 580.62
  • Catalog: Cytochrome P450
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Formyl Rifamycin

3-Formyl rifamycin is an intermediate of Rifampicin.

  • CAS Number: 13292-22-3
  • MF: C38H47NO13
  • MW: 725.779
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 855.4±65.0 °C at 760 mmHg
  • Melting Point: 182-184°C
  • Flash Point: 471.1±34.3 °C

MOPS sodium salt

MOPS sodium salt is commonly used as a buffering agent in biology. MOPS buffer can maintain the pH of mammalian cell culture media[1][2].

  • CAS Number: 71119-22-7
  • MF: C7H14NNaO4S
  • MW: 231.245
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 277-282°C
  • Flash Point: N/A

Bis[1,3]benzodioxolo[4,5-c:5',6'-g]azecin-13(5H)- one,4,6,7,14-tetrahydro-5,14-dimethyl-

Corycavine is an alkaloid that can be isolated from Corydalis remota[1].

  • CAS Number: 521-87-9
  • MF: C21H21NO5
  • MW: 367.40
  • Catalog: Others
  • Density: 1.28g/cm3
  • Boiling Point: 534.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 277.1ºC

D-Threitol

D-threitol serves as a antifreeze agent in the Alaskan beetle Upis ceramboides.

  • CAS Number: 2418-52-2
  • MF: C4H10O4
  • MW: 122.12000
  • Catalog: Others
  • Density: 1.43g/cm3
  • Boiling Point: 330ºC at 760mmHg
  • Melting Point: 88-90ºC(lit.)
  • Flash Point: 208.7ºC

MeOSuc-AAPV-AMC

MeOSuc-AAPV-AMC is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase (Km: 362 μM, Ex=380 nm, Em=460 nm)[1].

  • CAS Number: 72252-90-5
  • MF: C31H41N5O9
  • MW: 627.685
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 983.7±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 548.7±34.3 °C

Egg yolk lecithin

Lecithins, egg can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

  • CAS Number: 93685-90-6
  • MF: C5H5ClN2
  • MW:
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Butylphenol-d5

4-Butylphenol-d5 is the deuterium labeled 4-Butylphenol[1].

  • CAS Number: 1219795-04-6
  • MF: C10H14O
  • MW: 150.218
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 246.2±9.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 121.5±8.8 °C

23-Hydroxylongispinogenin

23-Hydroxylongispinogenin (12-Oleanene-3β,16β,23,28-tetrol) is extracted from Lysimachia heterogenea Klatt. Lysimachia heterogenea Klatt is a perennial herb, which is used as a folk medicine in subduing swelling and detoxicating in China. The effective fraction LH-1 of L. heterogene has antitumor activity[1].

  • CAS Number: 42483-24-9
  • MF: C30H50O4
  • MW: 474.71600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A