β-Boswellic acid is isolated from the gum resin of Boswellia serrate.β-Boswellic acid is a nonreducing-type inhibitor of the 5-lipoxygenase (5-LO) product formation either interacting directly with the 5-LO or blocking its translocation[1]. β-Boswellic acid inhibits the synthesis of DNA, RNA and protein in human leukemia HL-60 cells[2].
N,N′-Dibenzoyl-L-cystine is a cysteine derivative[1].
N1,N1,N3,N3-Tetramethylpropane-1,3-diamine-d18 is the deuterium labeled N1,N1,N3,N3-Tetramethylpropane-1,3-diamine[1].
(-)-Fenchone, a bicyclic monoterpene, is widely distributed in plants and found in essential oils from Thuja occidentalis. (-)-Fenchone is oxidized to 6-endo-hydroxyfenchone, 6-exo-hydroxyfenchone and 10-hydroxyfenchone derivatives by CYP2A6 and CYP2B6 in human liver microsomes with CYP2A6 playing a more important role than CYP2B6[1].
trans-N-Methyl-4-methoxyproline is a natural product that can be isolated from the stems of Petiveria alliacea and is also a Proline derivative[1].
N-Methyl lactam (Compound 3b), a peramiue analogue, has feeding-deterrent activity against adult weevils[1].
6-[(1R,2S)-2,3-dihydroxy-1-methoxy-3-methylbutyl]-7-methoxy- can be isolated from Angelica dahurica stem, for the first time from a plant source[1].
4-(2-Methylthiazol-4-yl)phenol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Gly-Asp is a Glycine (HY-Y0966) derivative[1].
3-Tolylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
2-Hydroxy-N,N,N-trimethylethan-1-aminium iodide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Spermine(N3BBB) is a click chemistry reagent containing an azide group and can be used for various biochemical studies[1].
Glutamic acid protease only can be found in fungi. Glutamic protease is a proteolytic enzyme containing a glutamic acid residue[1].
Methylisopelletierine is the immediate precursor of psueudopelletierine. Methylisopelletierine is derived from lysine and acetate[1].
Z-D-Arg-OH is an arginine derivative[1].
Ammonium bicarbonate is a bioactive chemical.
Arginylaspartic acid is a biologically active peptide.
5α-reductase-IN-1 is an inhibitor of 5α-reductase, used for the research of patterned alopecia in combination with minoxidil.
Resveratrol-3-O-sulfate (sodium) is the metabolite of Resveratrol[1].
Zinc stearate is a Zinc distearate. Zinc stearate can be used as an excipient, such as lubricants for tablets and capsules. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
Terminal deoxyribonucleotidyltransferase (TdT) catalyses the condensation of deoxyribonucleotide triphosphates onto the 3' hydroxyl ends of DNA strands and adds N-regions to gene segment junctions during V(D)J recombination. Terminal deoxyribonucleotidyltransferase is expressed in immature, pre-B, pre-T lymphoid cells, and acute lymphoblastic leukemia/lymphoma cells[1].
4,5-Dichloroveratrole is a chlorinated product formed by reaction of Veratryl alcohol (VE; HY-107858) with chlorine dioxide solution[1].
Aprepitant-d4 is the deuterium labeled Aprepitant[1].
Angiotensin (1-12) (human) is an endogenous substrate for the production of biologically active angiotensin peptides by a non-renin-dependent mechanism[1].
Pullulanase (R-enzyme) is a starch debranching enzyme, is often used in biochemical studies. Pullulanase hydrolyses the α-1,6 glucosidic linkages in starch, amylopectin, pullulan, and related oligosaccharides. Pullulanase converts polysaccharide into small fermentative sugars during saccharification[1].
MRS1186 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 7.66 nM.
1,3-Benzodioxole-5,6-diaminedihydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Tacalcitol monohydrate (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium.IC50 value:Target: Tacalcitol modulates immunological and inflammatory processes. Tacalcitol induces nerve growth factor production in epidermal keratinocytes.
SNX7886 is a potent protac degrader of CDK8/19. SNX7886 degrades CDK 8 and CDK 19 with 90% and 80% degradation in 293 cells, respectively[1].