MRS1186

Modify Date: 2025-08-24 20:52:30

MRS1186 Structure
MRS1186 structure
Common Name MRS1186
CAS Number 183721-03-1 Molecular Weight 341.75
Density N/A Boiling Point N/A
Molecular Formula C16H12ClN5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MRS1186


MRS1186 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 7.66 nM.

 Names

Name MRS1186

 MRS1186 Biological Activity

Description MRS1186 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 7.66 nM.
Related Catalog
Target

Ki: 7.66 nM (hA3AR)[1].

In Vitro MRS1186 (compound 2d) is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 7.66 nM[1].
References

[1]. Tafi A, et al. Pharmacophore based receptor modeling: the case of adenosine A3 receptor antagonists. An approach to the optimization of protein models. J Med Chem. 2006 Jul 13;49(14):4085-97.

 Chemical & Physical Properties

Molecular Formula C16H12ClN5O2
Molecular Weight 341.75
InChIKey SPZIDRYLSXDAEF-UHFFFAOYSA-N
SMILES CCC(=O)Nc1nc2ccc(Cl)cc2c2nc(-c3ccco3)nn12
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