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MRS1186

Names

[ CAS No. ]:
183721-03-1

[ Name ]:
MRS1186

Biological Activity

[Description]:

MRS1186 is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 7.66 nM.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor
Research Areas >> Others

[Target]

Ki: 7.66 nM (hA3AR)[1].


[In Vitro]

MRS1186 (compound 2d) is a potent and selective human Adenosine A3 receptor (hA3AR) antagonist, with a Ki of 7.66 nM[1].

[References]

[1]. Tafi A, et al. Pharmacophore based receptor modeling: the case of adenosine A3 receptor antagonists. An approach to the optimization of protein models. J Med Chem. 2006 Jul 13;49(14):4085-97.


[Related Small Molecules]

CGS 21680 hydrochloride | Preladenant | ZM 241385 | CPI-444 | SCH 58261 | Vipadenant | Istradefylline | Tozadenant | AZD-4635 | Capadenoson | 2-CL-IB-MECA | PSB-12379 | CD73-IN-1 | IB-MECA | Diprophylline

Chemical & Physical Properties

[ Molecular Formula ]:
C16H12ClN5O2

[ Molecular Weight ]:
341.75

Related Compounds

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